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Control barrier functions (CBFs) are a popular tool for safety certification of nonlinear dynamical control systems. Recently, CBFs represented as neural networks have shown great promise due to their expressiveness and applicability to a…

Machine Learning · Computer Science 2026-04-15 Nikolaus Vertovec , Frederik Baymler Mathiesen , Thom Badings , Luca Laurenti , Alessandro Abate

Coregulation of the expression of groups of genes has been extensively demonstrated empirically in bacterial and eukaryotic systems. Such coregulation can arise through the use of shared regulatory motifs, which allow the coordinated…

Machine Learning · Statistics 2016-04-12 Jonathan H. Warrell , Musa M. Mhlanga

We focus on a convolutional neural network (CNN), which has recently been utilized for fluid flow analyses, from the perspective on the influence of various operations inside it by considering some canonical regression problems with fluid…

Fluid Dynamics · Physics 2021-08-18 Masaki Morimoto , Kai Fukami , Kai Zhang , Aditya G. Nair , Koji Fukagata

In this paper, we analyse large random Boolean networks in terms of a constraint satisfaction problem. We first develop an algorithmic scheme which allows to prune simple logical cascades and under-determined variables, returning thereby…

Statistical Mechanics · Physics 2009-11-11 L. Correale , M. Leone , A. Pagnani , M. Weigt , R. Zecchina

Understanding the characteristics of neural networks is important but difficult due to their complex structures and behaviors. Some previous work proposes to transform neural networks into equivalent Boolean expressions and apply…

Machine Learning · Computer Science 2023-06-09 Yiping Tang , Kohei Hatano , Eiji Takimoto

This paper investigates the stabilization of probabilistic Boolean networks (PBNs) via a novel pinning control strategy based on network structure. In a PBN, the evolution equation of each gene switches among a collection of candidate…

Systems and Control · Electrical Eng. & Systems 2020-10-26 Lin Lin , Jinde Cao , Jianquan Lu , Jie Zhong

Despite their apparent simplicity, random Boolean networks display a rich variety of dynamical behaviors. Much work has been focused on the properties and abundance of attractors. The topologies of random Boolean networks with one input per…

Disordered Systems and Neural Networks · Physics 2009-11-11 Björn Samuelsson , Carl Troein

Random Boolean networks (RBNs) have been a popular model of genetic regulatory networks for more than four decades. However, most RBN studies have been made with random topologies, while real regulatory networks have been found to be…

Cellular Automata and Lattice Gases · Physics 2015-03-17 Rodrigo Poblanno-Balp , Carlos Gershenson

For years, we have been building models of gene regulatory networks, where recent advances in molecular biology shed some light on new structural and dynamical properties of such highly complex systems. In this work, we propose a novel…

Adaptation and Self-Organizing Systems · Physics 2009-09-30 Christian Darabos , Marco Tomassini , Mario Giacobini

Interactions between genes and gene products give rise to complex circuits that enable cells to process information and respond to external signals. Theoretical studies often describe these interactions using continuous, stochastic, or…

Molecular Networks · Quantitative Biology 2007-05-23 Madalena Chaves , Reka Albert , Eduardo D. Sontag

It is becoming increasingly appreciated that the signal transduction systems used by eukaryotic cells to achieve a variety of essential responses represent highly complex networks rather than simple linear pathways. While significant effort…

Molecular Networks · Quantitative Biology 2009-11-10 Kevin S. Brown , Colin C. Hill , Guillermo A. Calero , Kelvin H. Lee , James P. Sethna , Richard A. Cerione

In this paper we propose a new approach to quantum neural networks. Our multi-layer architecture avoids the use of measurements that usually emulate the non-linear activation functions which are characteristic of the classical neural…

Quantum Physics · Physics 2020-11-30 Viet Pham Ngoc , Herbert Wiklicky

Probabilistic Boolean Networks (PBNs) have been previously proposed so as to gain insights into complex dy- namical systems. However, identification of large networks and of the underlying discrete Markov Chain which describes their…

Machine Learning · Computer Science 2018-01-24 Ifigeneia Apostolopoulou , Diana Marculescu

Control Barrier Functions (CBFs) are utilized to ensure the safety of control systems. CBFs act as safety filters in order to provide safety guarantees without compromising system performance. These safety guarantees rely on the…

Systems and Control · Electrical Eng. & Systems 2025-06-30 Hongchao Zhang , Manan Tayal , Jackson Cox , Pushpak Jagtap , Shishir Kolathaya , Andrew Clark

We develop a method for training neural networks on Boolean data in which the values at all nodes are strictly $\pm 1$, and the resulting models are typically equivalent to networks whose nonzero weights are also $\pm 1$. The method…

Machine Learning · Computer Science 2026-02-20 Veit Elser , Manish Krishan Lal

Normalizing Flows (NF) are Generative models which transform a simple prior distribution into the desired target. They however require the design of an invertible mapping whose Jacobian determinant has to be computable. Recently introduced,…

Machine Learning · Computer Science 2025-09-18 Vincent Souveton , Arnaud Guillin , Jens Jasche , Guilhem Lavaux , Manon Michel

Recently, a general data driven numerical framework has been developed for learning and modeling of unknown dynamical systems using fully- or partially-observed data. The method utilizes deep neural networks (DNNs) to construct a model for…

Machine Learning · Computer Science 2022-05-18 Victor Churchill , Dongbin Xiu

Apart from the role the clustering coefficient plays in the definition of the small-world phenomena, it also has great relevance for practical problems involving networked dynamical systems. To study the impact of the clustering coefficient…

Physics and Society · Physics 2022-07-19 Robert E. Kooij , Nikolaj Horsevad Sørensen , Roland Bouffanais

Consider a large Boolean network with a feed forward structure. Given a probability distribution on the inputs, can one find, possibly small, collections of input nodes that determine the states of most other nodes in the network? To answer…

Information Theory · Computer Science 2013-05-23 Reinhard Heckel , Steffen Schober , Martin Bossert

A Boolean network is a finite state discrete time dynamical system. At each step, each variable takes a value from a binary set. The value update rule for each variable is a local function which depends only on a selected subset of…

Dynamical Systems · Mathematics 2017-08-10 Zuguang Gao , Xudong Chen , Tamer Başar