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We propose optimal Bayesian two-sample tests for testing equality of high-dimensional mean vectors and covariance matrices between two populations. In many applications including genomics and medical imaging, it is natural to assume that…

Methodology · Statistics 2021-12-07 Kyoungjae Lee , Kisung You , Lizhen Lin

In biomedical studies, testing for differences in covariance offers scientific insights beyond mean differences, especially when differences are driven by complex joint behavior between features. However, when differences in joint behavior…

Methodology · Statistics 2026-04-07 David Veitch , Yinqiu He , Jun Young Park

We study high-dimensional two-sample mean comparison and address the curse of dimensionality through data-adaptive projections. Leveraging the low-dimensional and localized signal structures commonly seen in single-cell genomics data, our…

Methodology · Statistics 2025-06-12 Tianyu Zhang , Jing Lei , Kathryn Roeder

Testing equality of mean vectors is a very commonly used criterion when comparing two multivariate random variables. Traditional tests such as Hotelling's T-squared become either unusable or output small power when the number of variables…

Methodology · Statistics 2020-03-17 Santu Ghosh , Deepak Nag Ayyala , Rafael Hellebuyck

Subsampled Randomized Hadamard Transform (SRHT), a popular random projection method that can efficiently project a $d$-dimensional data into $r$-dimensional space ($r \ll d$) in $O(dlog(d))$ time, has been widely used to address the…

Machine Learning · Computer Science 2020-10-07 Zijian Lei , Liang Lan

This paper considers the asymptotic power of likelihood ratio test (LRT) for the identity test when the dimension p is large compared to the sample size n. The asymptotic distribution of LRT under alternatives is given and an explicit…

Statistics Theory · Mathematics 2013-02-15 Cheng Wang , Longbing Cao , Baiqi Miao

Random projection has been widely used in data classification. It maps high-dimensional data into a low-dimensional subspace in order to reduce the computational cost in solving the related optimization problem. While previous studies are…

Machine Learning · Computer Science 2014-02-24 Lijun Zhang , Mehrdad Mahdavi , Rong Jin , Tianbao Yang , Shenghuo Zhu

Permutation tests are widely recognized as robust alternatives to tests based on normal theory. Random permutation tests have been frequently employed to assess the significance of variables in linear models. Despite their widespread use,…

Methodology · Statistics 2023-12-29 Leying Guan

Extensive literature exists on how to test for normality, especially for identically and independently distributed (i.i.d) processes. The case of dependent samples has also been addressed, but only for scalar random processes. For this…

Signal Processing · Electrical Eng. & Systems 2022-02-17 Sara Elbouch , Olivier Michel , Pierre Comon

Testing the equality of two high-dimensional mean vectors is a fundamental problem in multivariate analysis. While the classical Hotelling's $T^2$ test is optimal in low-dimensional settings, it fails when the dimension $p$ is comparable to…

Methodology · Statistics 2026-05-22 Minsub Shin , Kwangok Seo , Sang Han Lee , Johan Lim

Many testing problems are readily amenable to randomised tests such as those employing data splitting. However despite their usefulness in principle, randomised tests have obvious drawbacks. Firstly, two analyses of the same dataset may…

Methodology · Statistics 2024-09-05 F. Richard Guo , Rajen D. Shah

We develop a projected Wasserstein distance for the two-sample test, a fundamental problem in statistics and machine learning: given two sets of samples, to determine whether they are from the same distribution. In particular, we aim to…

Machine Learning · Statistics 2024-04-01 Jie Wang , Rui Gao , Yao Xie

Multivariate linear regressions are widely used statistical tools in many applications to model the associations between multiple related responses and a set of predictors. To infer such associations, it is often of interest to test the…

Statistics Theory · Mathematics 2019-10-07 Yinqiu He , Tiefeng Jiang , Jiyang Wen , Gongjun Xu

Many tests have been proposed to remedy the classical Hotelling's $T^2$ test in the "large $p$, small $n$" paradigm, but the existence of an optimal sum-of-squares type test has not been explored. This paper shows that under certain…

Methodology · Statistics 2018-02-02 Jun Li , Yumou Qiu , Lingjun Li

We investigate the problem of testing the global null in the high-dimensional regression models when the feature dimension $p$ grows proportionally to the number of observations $n$. Despite a number of prior work studying this problem,…

Methodology · Statistics 2020-10-06 Yue Li , Ilmun Kim , Yuting Wei

We consider linear regression problems with a varying number of random projections, where we provably exhibit a double descent curve for a fixed prediction problem, with a high-dimensional analysis based on random matrix theory. We first…

Machine Learning · Computer Science 2023-03-15 Francis Bach

Hotelling's T-squared test is a classical tool to test if the normal mean of a multivariate normal distribution is a specified one or the means of two multivariate normal means are equal. When the population dimension is higher than the…

Statistics Theory · Mathematics 2021-08-17 Tiefeng Jiang , Ping Li

In this paper, we give an explanation to the failure of two likelihood ratio procedures for testing about covariance matrices from Gaussian populations when the dimension is large compared to the sample size. Next, using recent central…

Statistics Theory · Mathematics 2011-09-09 Zhidong Bai , Dandan Jiang , Jian-feng Yao , Shurong Zheng

Two-sample tests are important areas aiming to determine whether two collections of observations follow the same distribution or not. We propose two-sample tests based on integral probability metric (IPM) for high-dimensional samples…

Machine Learning · Statistics 2023-04-21 Jie Wang , Minshuo Chen , Tuo Zhao , Wenjing Liao , Yao Xie

Power-enhanced tests with high-dimensional data have received growing attention in theoretical and applied statistics in recent years. Existing tests possess their respective high-power regions, and we may lack prior knowledge about the…

Methodology · Statistics 2021-10-01 Xiufan Yu , Danning Li , Lingzhou Xue , Runze Li