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Understanding the dynamics of ions in nanopores is essential for applications ranging from single-molecule detection to DNA sequencing. We show both analytically and by means of molecular dynamics simulations that under specific conditions…

Soft Condensed Matter · Physics 2011-06-08 Matt Krems , Massimiliano Di Ventra

Ionic Coulomb blockade is one of the mesoscopic effects in ion transport revealing the quantized nature of ionic charges, which is of crucial importance to our understanding of the sub-continuum transport in nanofluidics and the mechanism…

Mesoscale and Nanoscale Physics · Physics 2020-12-29 Fanfan Chen , Zonglin Gu , Chunxiao Zhao , Yuang Chen , Xiaowei Jiang , Zhi He , Yuxian Lu , Ruhong Zhou , Jiandong Feng

Ionic Coulomb blockade (ICB) is an electrostatic phenomenon recently discovered in low-capacitance ion channels/nanopores. Depending on the fixed charge that is present, ICB strongly and selectively influences the ease with which a given…

Biological Physics · Physics 2017-07-31 I. Kh. Kaufman , W. A. T. Gibby , D. G. Luchinsky , P. V. E. McClintock

Ionic Coulomb blockade in nanopores is a phenomenon that shares some similarities but also differences with its electronic counterpart. Here, we investigate extensively this phenomenon using all-atom molecular dynamics of ionic transport…

Mesoscale and Nanoscale Physics · Physics 2017-12-27 Hiroya Tanaka , Hideo Iizuka , Yuriy V. Pershin , Massimiliano Di Ventra

When channels were scaled down to the size of hydrated ions, ionic Coulomb blockade was discovered. However, the experimental CB phenomenon was rarely reported since Feng et.al., discovered in MoS2 nanopore. By using latent-track membranes…

Soft Condensed Matter · Physics 2022-11-18 Yanbo Xie , Deli Shi , Wenhui Wang , Ziheng Wang

We report an experimental study of the influences of the fixed charge and bulk ionic concentrations on the conduction of biological ion channels, and we consider the results within the framework of the ionic Coulomb blockade model of…

Subcellular Processes · Quantitative Biology 2016-12-09 I. Kh. Kaufman , O. A. Fedorenko , D. G. Luchinsky , W. A. T. Gibby , S. K. Roberts. P. V. E. McClintock , R. S. Eisenberg

Recent advances in nanofluidics have allowed exploration of ion transport down to molecular scale confinement, yet artificial porins are still far from reaching the advanced functionalities of biological ion machinery. Achieving single ion…

Soft Condensed Matter · Physics 2020-05-12 Nikita Kavokine , Sophie Marbach , Alessandro Siria , Lydéric Bocquet

We consider a class of systems where, due to the large mismatch of dielectric constants, the Coulomb interaction is approximately one-dimensional. Examples include ion channels in lipid membranes and water filled nanopores in silicon or…

Statistical Mechanics · Physics 2015-06-25 A. Kamenev , J. Zhang , A. I. Larkin , B. I. Shklovskii

Assuming that the selectivity filter of KcsA potassium ion channel may exhibit quantum coherence, we extend a previous model by Vaziri and Plenio (2010) to take into account Coulomb repulsion between potassium ions. We show that typical ion…

Biological Physics · Physics 2018-07-04 N. De March , S. D. Prado , L. G. Brunnet

The rate-equation approach is used to describe sequential tunneling through a molecular junction in the Coulomb blockade regime. Such device is composed of molecular quantum dot (with discrete energy levels) coupled with two metallic…

Mesoscale and Nanoscale Physics · Physics 2009-11-11 Kamil Walczak

We use Brownian dynamics simulations to study the permeation properties of a generic electrostatic model of a biological ion channel as a function of the fixed charge $Q_f$ at its selectivity filter. We reconcile the recently-discovered…

Biological Physics · Physics 2013-12-05 I. Kaufman , D. G. Luchinsky , R. Tindjong , P. V. E. McClintock , R. S. Eisenberg

We report finite-bias characteristics of electrical transport through phosphorus donors in silicon nanoscale transistors, in which we observe inelastic-cotunneling current in the Coulomb blockade region. The cotunneling current appears like…

Mesoscale and Nanoscale Physics · Physics 2023-01-25 Pooja Yadav , Soumya Chakraborty , Daniel Moraru , Arup Samanta

We study the transport through a quantum dot coupled to two leads by single-mode point contacts. The linear conductance is calculated analytically as a function of a gate voltage and temperature T in the case when transmission coefficients…

Condensed Matter · Physics 2009-10-28 A. Furusaki , K. A. Matveev

We theoretically investigate resonant tunneling through a linear array of quantum dots with subsequent tunnel coupling. We consider two limiting cases: (i) strong Coulomb blockade, where only one extra electron can be present in the array…

Mesoscale and Nanoscale Physics · Physics 2009-10-31 M. R. Wegewijs , Yu. V. Nazarov

Electronic transport through a two-path triple-quantum-dot system with two source leads and one drain is studied. By separating the conductance of the two double dot paths, we are able to observe double dot and triple dot physics in…

Mesoscale and Nanoscale Physics · Physics 2016-08-03 M. Kotzian , F. Gallego-Marcos , G. Platero , R. J. Haug

We study low-temperature transport through carbon nanotube quantum dots in the Coulomb blockade regime coupled to niobium-based superconducting leads. We observe pronounced conductance peaks at finite source-drain bias, which we ascribe to…

Mesoscale and Nanoscale Physics · Physics 2009-05-25 K. Grove-Rasmussen , H. I. Jørgensen , B. M. Andersen , J. Paaske , T. S. Jespersen , J. Nygård , K. Flensberg , P. E. Lindelof

The role of Coulomb interaction between the mobile particles in ionic conductors is still under debate. To clarify this aspect we perform Monte Carlo simulations on two simple lattice models (Counter Ion Model and Random Energy Model) which…

Disordered Systems and Neural Networks · Physics 2009-11-07 J. Reinisch , A. Heuer

We study numerically the influence of strong Coulomb repulsion on the current through molecular wires that are driven by external electromagnetic fields. The molecule is described by a tight-binding model whose first and last site is…

Mesoscale and Nanoscale Physics · Physics 2007-05-23 Franz J. Kaiser , Peter Hänggi , Sigmund Kohler

Nonlinear current voltage characteristics and in some cases also step like characteristics were observed in diamond like carbon films. We suggest that the transport mechanism is tunneling between conducting nanoparticles in the films and…

Materials Science · Physics 2008-04-15 S. S. Tinchev , S. Alexandrova , E. Valcheva

Ionic transport in nanopores is a fundamentally and technologically important problem in view of its occurrence in biological processes and its impact on novel DNA sequencing applications. Using microscopic calculations, here we show that…

Soft Condensed Matter · Physics 2009-09-26 Michael Zwolak , Johan Lagerqvist , Massimiliano Di Ventra
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