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A major strength of iterative algorithms used in positron emission tomography (PET) lies in their abilities to introduce precise models of the physics at play, which includes the statistical nature of the detection processes, and a detailed…

Medical Physics · Physics 2022-04-26 Adrien Hourlier , Debora Giovagnoli , Virgile Bekaert , Frederic Boisson , David Brasse

Positional single photon incidence response (P-SPIR) theory is researched in this paper to generate more accurate PSF-contained system matrix simply and quickly. The method has been proved highly effective to improve the spatial resolution…

X-ray cone-beam computed tomography (CT) has the notable features such as high efficiency and precision, and is widely used in the fields of medical imaging and industrial non-destructive testing, but the inherent imaging degradation…

Optics · Physics 2015-06-19 Hua Zhang , Kuidong Huang , Yikai Shi , Zhe Xu

Inter-crystal scattering (ICS) in Positron Emission Tomography (PET) is commonly regarded as a degradation effect that might compromise the image spatial resolution. In parallel, the inclusion of ICS events has also been recognized as a…

Medical Physics · Physics 2026-05-12 Jorge Roser , Hong Phuc Vo , Rebecca Kantorek , Steven Seeger , Magdalena Rafecas

Positron Emission Tomography (PET) scanners are usually designed with the goal to obtain the best compromise between sensitivity, resolution, field-of-view size, and cost. Therefore, it is difficult to improve the resolution of a PET…

Medical Physics · Physics 2023-07-18 Pablo Galve , Alejandro Lopez-Montes , Jose M Udias , Stephen C Moore , Joaquin L Herraiz

Accessing the point-spread function (PSF) of a complex optical system is important for a variety of imaging applications. However, placing an invasive point source is often impractical, and estimating it blindly with multiple frames is slow…

Optics · Physics 2020-09-23 Tengfei Wu , Jonathan Dong , Sylvain Gigan

The knowledge of the exact structure of the optical system PSF enables a high-quality image reconstruction in fluorescence microscopy. Accurate PSF models account for the vector nature of light and the phase and amplitude modifications.…

Accurate blur estimation is essential for high-performance imaging across various applications. Blur is typically represented by the point spread function (PSF). In this paper, we propose a physics-informed PSF learning framework for…

Computer Vision and Pattern Recognition · Computer Science 2025-03-12 Liqun Chen , Yuxuan Li , Jun Dai , Jinwei Gu , Tianfan Xue

SPECT (Single-photon Emission Computerized Tomography) and PET (Positron Emission Tomography) are essential medical imaging tools, for which the sampling angle number, scan time should be chosen carefully to compromise between image quality…

Medical Physics · Physics 2015-06-16 Xiaolin Zhou , Minkai Yun , Xuexiang Cao , Shuangquan Liu , Lu Wang , Xianchao Huang , Long Wei

We developed a positron emission tomography (PET) system for multiple-isotope imaging. Our PET system, named multiple-isotope PET (MI-PET), can distinguish between different tracer nuclides using coincidence measurement of prompt…

Point spread function (PSF) engineering is vital for precisely controlling the focus of light in computational imaging, with applications in neural imaging, fluorescence microscopy, and biophotonics. The PSF is derived from the magnitude of…

Optics · Physics 2025-04-22 Aleksey Valouev

Reconstruction of the point spread function (PSF) plays an important role in many areas of astronomy, including photometry, astrometry, galaxy morphology, and shear measurement. The atmospheric and instrumental effects are the two main…

Instrumentation and Methods for Astrophysics · Physics 2024-04-25 Pedro Alonso , Jun Zhang , Cong Liu

Positron emission tomographs (PET) do not measure an image directly. Instead, they measure at the boundary of the field-of-view (FOV) of PET tomograph a sinogram that consists of measurements of the sums of all the counts along the lines…

Differentiable rendering has been widely adopted in computer graphics as a powerful approach to inverse problems, enabling efficient gradient-based optimization by differentiating the image formation process with respect to millions of…

Computed tomography (CT) reconstructs volumetric images using X-ray projection data acquired from multiple angles around an object. For low-dose or sparse-view CT scans, the classic image reconstruction algorithms often produce severe noise…

Medical Physics · Physics 2024-03-04 Wenxiang Cong , Wenjun Xia , Ge Wang

The point-spread function (PSF) of an imaging system describes the response of the system to a point source. Accurately determining the PSF enables one to correct for the combined effects of focussing and scattering within the imaging…

Instrumentation and Methods for Astrophysics · Physics 2022-11-01 Stefan Johann Hofmeister , Michael Hahn , Daniel Wolf Savin

This Point spread function (PSF) plays a crucial role in many computational imaging applications, such as shape from focus/defocus, depth estimation, and fluorescence microscopy. However, the mathematical model of the defocus process is…

Computer Vision and Pattern Recognition · Computer Science 2022-09-20 Renzhi He , Yan Zhuang , Boya Fu , Fei Liu

A sparsity-exploiting algorithm intended for few-view Single Photon Emission Computed Tomography (SPECT) reconstruction is proposed and characterized. The algorithm models the object as piecewise constant subject to a blurring operation. To…

Medical Physics · Physics 2012-12-05 Paul A Wolf , Jakob H Jørgensen , Taly G Schmidt , Emil Y Sidky

An image or volume of interest in positron emission tomography (PET) is reconstructed from pairs of gamma rays emitted from a radioactive substance. Many image reconstruction methods are based on estimation of pixels or voxels on some…

Signal Processing · Electrical Eng. & Systems 2019-06-18 Azra Tafro , Damir Seršić , Ana Sović Kržić

The reconstruction of dynamic positron emission tomography (PET) images from noisy projection data is a significant but challenging problem. In this paper, we introduce an unsupervised learning approach, Non-negative Implicit Neural…

Computer Vision and Pattern Recognition · Computer Science 2025-06-25 Chaozhi Zhang , Wenxiang Ding , Roy Y. He , Xiaoqun Zhang , Qiaoqiao Ding
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