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We present an analytical theory for heteropolymer deformation, as exemplified experimentally by stretching of single protein molecules. Using a mean-field replica theory, we determine phase diagrams for stress-induced unfolding of typical…

Statistical Mechanics · Physics 2009-11-07 Phillip L. Geissler , Eugene I. Shakhnovich

Fluctuations of the thermal or classical component of the van der Waals force between two dielectric slabs, modelled as an ensemble of polarizable dipoles which interact via the usual electrostatic dipole-dipole interaction, are evaluated.…

Statistical Mechanics · Physics 2015-06-15 D. S. Dean , V. A. Parsegian , R. Podgornik

Single-molecule atomic force spectroscopy probes elastic properties of titin, ubiquitin and other relevant proteins. We explain bioprotein folding dynamics under both length- and force-clamp by modeling polyprotein modules as particles in a…

Statistical Mechanics · Physics 2016-11-17 L. L. Bonilla , A. Carpio , A. Prados

The fluctuations of the current for the one-dimensional totally asymmetric exclusion process with $L$ sites are studied in the relaxation regime of times $T\sim L^{3/2}$. Using Bethe ansatz for the periodic system with an evolution…

Statistical Mechanics · Physics 2015-01-22 Sylvain Prolhac

The way tension propagates along a chain is a key to govern many of anomalous dynamics in macromolecular systems. After introducing the weak and the strong force regimes of the tension propagation, we focus on the latter, in which the…

Soft Condensed Matter · Physics 2015-04-27 Takuya Saito , Takahiro Sakaue

We consider how active forces modeled as non-thermal random noise affect the average dynamical properties of a Rouse polymer. As the power spectrum of the noise is not known we keep the analytical treatment as generic as possible and then…

Statistical Mechanics · Physics 2017-05-23 Dino Osmanovic , Yitzhak Rabin

We study the conformations of polymer chains in a poor solvent, with and without bending rigidity, by means of a simple statistical mechanics model. This model can be exactly solved for chains of length up to N=55 using exact enumeration…

Statistical Mechanics · Physics 2007-11-26 Anthony J. Guttmann , Jesper L. Jacobsen , Iwan Jensen , Sanjay Kumar

It has been recently shown that randomly charged surfaces can exhibit long range electrostatic interactions even when they are net neutral. These forces depend on the specific realization of charge disorder and thus exhibit sample to sample…

Soft Condensed Matter · Physics 2011-12-30 David S. Dean , Ali Naji , Rudolf Podgornik

In this paper we compare two polymer stretching experiments. The outcome of both experiments is a force-extension relation. We use a one-dimensional model to show that in general the two quantities are not equal. In certain limits, however,…

Statistical Mechanics · Physics 2009-11-11 Erik Van der Straeten , Jan Naudts

The fluctuation-dissipation relation tells that dissipation always accompanies with thermal fluctuations. Relativistic fluctuating hydrodynamics is used to study the effects of the thermal fluctuations in the hydrodynamic expansion of the…

Nuclear Theory · Physics 2019-02-20 Tetsufumi Hirano , Ryuichi Kurita , Koichi Murase

Fluctuation theorems are fundamental results in non-equilibrium thermodynamics. Considering the fluctuation theorem with respect to the entropy production and an observable, we derive a new thermodynamic uncertainty relation which also…

Statistical Mechanics · Physics 2022-02-02 Gianluca Francica

We analyze free energy estimators from simulation trials mimicking single-molecule pulling experiments on a neck linker of a kinesin motor. For that purpose, we have performed a version of steered molecular dynamics (SMD) calculations. The…

Biomolecules · Quantitative Biology 2018-09-19 Michał Świątek , Ewa Gudowska-Nowak

We experimentally study the fluctuations of the work done by an external Gaussian random force on two different stochastic systems coupled to a thermal bath: a colloidal particle in an optical trap and an atomic force microscopy cantilever.…

Statistical Mechanics · Physics 2010-04-20 Juan Ruben Gomez-Solano , Ludovic Bellon , Artyom Petrosyan , Sergio Ciliberto

Using molecular dynamic simulation, we study the stretching of an adsorbed homopolymer in a poor solvent with one end held at a distance $z_e$ from the substrate. We measure the vertical force $f$ on the end of the chain as a function of…

Soft Condensed Matter · Physics 2009-11-10 Franck Celestini , Thoma Frisch , Xabier Oyharcabal

The dynamical response of a tethered semiflexible polymer with self-attractive interactions and subjected to an external force field is numerically investigated by varying stiffness and self-interaction strength. The chain is confined in…

Soft Condensed Matter · Physics 2022-11-09 A. Lamura

We present results for the fluctuations of the displacement of a tracer particle on a planar lattice pulled by a step force in the presence of impenetrable, immobile obstacles. The fluctuations perpendicular to the applied force are…

Statistical Mechanics · Physics 2018-02-06 Sebastian Leitmann , Thomas Schwab , Thomas Franosch

Predicting the time and temperature dependent behavior of polymer networks under complex loading is essential for the design of advanced elastomeric materials. Many practical applications involve combinations of deformation modes, such as…

Soft Condensed Matter · Physics 2025-12-12 Volker Kraus , Wolfgang Hamm , Miklos Zrinyi

Polymer stretching in random smooth flows is investigated within the framework of the FENE dumbbell model. The advecting flow is Gaussian and short-correlated in time. The stationary probability density function of polymer extension is…

Chaotic Dynamics · Physics 2007-05-23 M. Martins Afonso , D. Vincenzi

Topological entanglements in polymers are mimicked by sliding rings (slip-links) which enforce pair contacts between monomers. We study the force-extension curve for linear polymers in which slip-links create additional loops of variable…

Statistical Mechanics · Physics 2009-11-07 Ralf Metzler , Yacov Kantor , Mehran Kardar

Taking into account the nonequivalence of fixed-force and fixed-length ensembles in the weak-force regime, equations of state are derived that describe the equilibrium extension or compression of an ideal Gaussian polymer chain in response…

Soft Condensed Matter · Physics 2007-05-23 Richard M. Neumann