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The article presents several approaches to the blockmodeling of multilevel network data. Multilevel network data consist of networks that are measured on at least two levels (e.g. between organizations and people) and information on ties…

Methodology · Statistics 2014-05-26 Aleš Žiberna

Modular structure is pervasive in many complex networks of interactions observed in natural, social and technological sciences. Its study sheds light on the relation between the structure and function of complex systems. Generally speaking,…

Data Analysis, Statistics and Probability · Physics 2010-05-10 Alex Arenas , Javier Borge-Holthoefer , Sergio Gomez , Gorka Zamora-Lopez

The representation of complex systems as networks is inappropriate for the study of certain problems. We show several examples of social, biological, ecological and technological systems where the use of complex networks gives very limited…

Physics and Society · Physics 2013-04-02 Ernesto Estrada , Juan A. Rodriguez-Velazquez

The identification of essential proteins in protein-protein interaction networks (PINs) can help to discover drug targets and prevent disease. In order to improve the accuracy of the identification of essential proteins, researchers…

Molecular Networks · Quantitative Biology 2023-12-08 Haoyue Wang , Li Pan , Bo Yang , Junqiang Jiang , Wenbin Li

Real-world multilayer networks can be very large and there can be multiple choices regarding what should be modeled as a layer. Therefore, there is a need for their effective storage and manipulation. Currently, multilayer network analysis…

Databases · Computer Science 2023-05-16 Georgios Panayiotou , Matteo Magnani , Bruno Pinaud

The complexity of many biological, social and technological systems stems from the richness of the interactions among their units. Over the past decades, a great variety of complex systems has been successfully described as networks whose…

Modern social networks frequently encompass multiple distinct types of connectivity information; for instance, explicitly acknowledged friend relationships might complement behavioral measures that link users according to their actions or…

Social and Information Networks · Computer Science 2015-06-17 Brandon Oselio , Alex Kulesza , Alfred O. Hero

Transmission matrices, mapping the propagation of light from one end of the tissue to the other, form an important mathematical tool in the analysis of tissue scattering and the design of wavefront shaping systems. To understand the…

Optics · Physics 2025-04-01 Anat Levin , Marina Alterman

In this paper, we consider the statistical analysis of a protein interaction network. We propose a Bayesian model that uses a hierarchy of probabilistic assumptions about the way proteins interact with one another in order to: (i) identify…

Molecular Networks · Quantitative Biology 2007-11-15 Edoardo M Airoldi , David M Blei , Stephen E Fienberg , Eric P Xing

The use of patent citation networks as research tools is becoming increasingly commonplace in the field of innovation studies. However, these networks rarely consider the contexts in which these citations are generated and are generally…

Physics and Society · Physics 2022-05-17 Kyle Higham , Martina Contisciani , Caterina De Bacco

Multi-layered social networks reflect complex relationships existing in modern interconnected IT systems. In such a network each pair of nodes may be linked by many edges that correspond to different communication or collaboration user…

Social and Information Networks · Computer Science 2012-10-19 Piotr Bródka , Krzysztof Skibicki , Przemysław Kazienko , Katarzyna Musiał

The protein-protein interaction (PPI) network provides an overview of the complex biological reactions vital to an organism's metabolism and survival. Even though in the past PPI network were compared across organisms in detail, there has…

Computer Vision and Pattern Recognition · Computer Science 2023-10-27 Long-Huei Chen , Mohana Prasad Sathya Moorthy , Pratyaksh Sharma

The large-scale properties of chemical reaction systems, such as the metabolism, can be studied with graph-based methods. To do this, one needs to reduce the information -- lists of chemical reactions -- available in databases. Even for the…

Molecular Networks · Quantitative Biology 2009-09-25 Petter Holme

Assessing where and how information is stored in biological networks (such as neuronal and genetic networks) is a central task both in neuroscience and in molecular genetics, but most available tools focus on the network's structure as…

Information Theory · Computer Science 2023-02-24 Clifford Bohm , Douglas Kirkpatrick , Victoria Cao , Christoph Adami

Network or graph structures are ubiquitous in the study of complex systems. Often, we are interested in complexity trends of these system as it evolves under some dynamic. An example might be looking at the complexity of a food web as…

Information Theory · Computer Science 2007-07-16 Russell K. Standish

We address the issue of the reducibility of the dynamics on a multilayer network to an equivalent process on an aggregated single-layer network. As a typical example of models for opinion formation in social networks, we implement the voter…

Physics and Society · Physics 2016-02-08 Marina Diakonova , Vincenzo Nicosia , Vito Latora , Maxi San Miguel

Pathway enrichment analysis has become a key tool for biomedical researchers to gain insight into the underlying biology of differentially expressed genes, proteins and metabolites. It reduces complexity and provides a system-level view of…

Methodology · Statistics 2016-06-24 Jing Ma , Ali Shojaie , George Michailidis

Many real world systems need to operate on heterogeneous information networks that consist of numerous interacting components of different types. Examples include systems that perform data analysis on biological information networks; social…

Artificial Intelligence · Computer Science 2017-07-26 Parisa Kordjamshidi , Sameer Singh , Daniel Khashabi , Christos Christodoulopoulos , Mark Summons , Saurabh Sinha , Dan Roth

What is a complex network? How do we characterize complex networks? Which systems can be studied from a network approach? In this text, we motivate the use of complex networks to study and understand a broad panoply of systems, ranging from…

Physics and Society · Physics 2007-11-27 Pedro G. Lind

Latent variable models for network data extract a summary of the relational structure underlying an observed network. The simplest possible models subdivide nodes of the network into clusters; the probability of a link between any two nodes…

Machine Learning · Computer Science 2012-07-03 Konstantina Palla , David Knowles , Zoubin Ghahramani