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Cluster analysis of biological samples using gene expression measurements is a common task which aids the discovery of heterogeneous biological sub-populations having distinct mRNA profiles. Several model-based clustering algorithms have…

Methodology · Statistics 2012-01-30 Alberto Cozzini , Ajay Jasra , Giovanni Montana

Although machine learning is increasingly applied in control approaches, only few methods guarantee certifiable safety, which is necessary for real world applications. These approaches typically rely on well-understood learning algorithms,…

Machine Learning · Computer Science 2020-06-16 Armin Lederer , Markus Kessler , Sandra Hirche

Given a random sample of observations, mixtures of normal densities are often used to estimate the unknown continuous distribution from which the data come. Here we propose the use of this semiparametric framework for testing symmetry about…

Methodology · Statistics 2012-04-23 Silvia Bacci , Francesco Bartolucci

Consider a population consisting of clusters of sampling units, evolving temporally, spatially, or according to other dynamics. We wish to monitor the evolution of its means, medians, or other parameters. For administrative convenience and…

Methodology · Statistics 2020-04-30 Jiahua Chen , Yukun Liu , James Zidek

Most cluster randomized trials (CRTs) randomize fewer than 30-40 clusters in total. When performing inference for such ``small'' CRTs, it is important to use methods that appropriately account for the small sample size. When the generalized…

Methodology · Statistics 2025-12-01 Shifeng Sun , Xueqi Wang , Zhuoran Hou , Elizabeth L. Turner

Hyperbolic space is increasingly used for hierarchical, tree-like, and network-structured data, but likelihood-based density modeling on hyperbolic space remains relatively limited. This paper develops finite mixture modeling with isotropic…

Methodology · Statistics 2026-04-29 Kisung You

This paper is concerned with an important issue in finite mixture modelling, the selection of the number of mixing components. We propose a new penalized likelihood method for model selection of finite multivariate Gaussian mixture models.…

Methodology · Statistics 2013-01-17 Tao Huang , Heng Peng , Kun Zhang

We investigate a state discrimination problem in operationally the most general framework to use a probability, including both classical, quantum theories, and more. In this wide framework, introducing closely related family of ensembles…

Quantum Physics · Physics 2015-05-13 Gen Kimura , Takayuki Miyadera , Hideki Imai

We study the following fundamental hypothesis testing problem, which we term Gaussian mean testing. Given i.i.d. samples from a distribution $p$ on $\mathbb{R}^d$, the task is to distinguish, with high probability, between the following…

Statistics Theory · Mathematics 2022-10-26 Ilias Diakonikolas , Daniel M. Kane , Ankit Pensia

The consistency of the maximum likelihood estimator for mixtures of elliptically-symmetric distributions for estimating its population version is shown, where the underlying distribution $P$ is nonparametric and does not necessarily belong…

Statistics Theory · Mathematics 2024-10-14 Pietro Coretto , Christian Hennig

Motivated by the likelihood ratio test under the Gaussian assumption, we develop a maximum sum-of-squares test for conducting hypothesis testing on high dimensional mean vector. The proposed test which incorporates the dependence among the…

Methodology · Statistics 2015-10-21 Xianyang Zhang

The exponential family is well known in machine learning and statistical physics as the maximum entropy distribution subject to a set of observed constraints, while the geometric mixture path is common in MCMC methods such as annealed…

Machine Learning · Computer Science 2021-01-18 Rob Brekelmans , Frank Nielsen , Alireza Makhzani , Aram Galstyan , Greg Ver Steeg

Bivariate count models having one marginal and the other conditionals being of the Poissons form are called pseudo-Poisson distributions. Such models have simple exible dependence structures, possess fast computation algorithms and generate…

Applications · Statistics 2023-06-08 Banoth Veeranna , B. G. Manjunath , B. Shobha

Many experiments in medicine and ecology can be conveniently modeled by finite Gaussian mixtures but face the problem of dealing with small data sets. We propose a robust version of the estimator based on self-regression and sparsity…

Computation · Statistics 2014-10-09 Stephane Chretien

The semi-empirical nature of best-estimate models closing the balance equations of thermal-hydraulic (TH) system codes is well-known as a significant source of uncertainty for accuracy of output predictions. This uncertainty, called model…

Methodology · Statistics 2023-09-11 Guillaume Damblin , François Bachoc , Sandro Gazzo , Lucia Sargentini , Alberto Ghione

Non-Gaussian likelihoods are essential for modelling complex real-world observations but pose significant computational challenges in learning and inference. Even with Gaussian priors, non-Gaussian likelihoods often lead to analytically…

Machine Learning · Statistics 2024-10-29 Thang D. Bui

In several interesting applications one is faced with the problem of simultaneous binary hypothesis testing and parameter estimation. Although such joint problems are not infrequent, there exist no systematic analysis in the literature that…

Statistics Theory · Mathematics 2009-11-25 George V. Moustakides

A fundamental challenge in approximating an unknown density using finite Gaussian mixture models is selecting the number of mixture components, also known as order. Traditional approaches choose a single best model using information…

Methodology · Statistics 2025-06-25 Alessandro Casa , Davide Ferrari

Mixtures of experts probabilistically divide the input space into regions, where the assumptions of each expert, or conditional model, need only hold locally. Combined with Gaussian process (GP) experts, this results in a powerful and…

Machine Learning · Statistics 2019-05-31 Charles W. L. Gadd , Sara Wade , Alexis Boukouvalas

Conditional correlation networks, within Gaussian Graphical Models (GGM), are widely used to describe the direct interactions between the components of a random vector. In the case of an unlabelled Heterogeneous population, Expectation…

Statistics Theory · Mathematics 2022-03-09 Thomas Lartigue , Stanley Durrleman , Stéphanie Allassonnière