Related papers: Map-Reduce Parallelization of Motif Discovery
Time Series Motif Discovery (TSMD) identifies repeating patterns in time series data, but its unsupervised nature might result in motifs that are not interesting to the user. To address this, we propose a framework that allows the user to…
Distributed maximization of a submodular function in the MapReduce (MR) model has received much attention, culminating in two frameworks that allow a centralized algorithm to be run in the MR setting without loss of approximation, as long…
Genome sequencing has become a central focus in computational biology. A genome study typically begins with sequencing, which produces millions to billions of short DNA fragments known as reads. Read mapping aligns these reads to a…
The persistent homology pipeline includes the reduction of a, so-called, boundary matrix. We extend the work of Bauer et al. (2014) and Chen et al. (2011) where they show how to use dependencies in the boundary matrix to adapt the reduction…
Inverse design of short single-stranded RNA and DNA sequences (aptamers) is the task of finding sequences that satisfy a set of desired criteria. Relevant criteria may be, for example, the presence of specific folding motifs, binding to…
The marginal maximum a posteriori probability (MAP) estimation problem, which calculates the mode of the marginal posterior distribution of a subset of variables with the remaining variables marginalized, is an important inference problem…
Molecular property prediction (MPP) is a cornerstone of drug discovery and materials science, yet conventional deep learning approaches depend on large labeled datasets that are often unavailable. Few-shot Molecular property prediction…
With recent advancements in large language models, methods like chain-of-thought prompting to elicit reasoning chains have been shown to improve results on reasoning tasks. However, tasks that require multiple steps of reasoning still pose…
Within the context of topological data analysis, the problems of identifying topological significance and matching signals across datasets are important and useful inferential tasks in many applications. The limitation of existing solutions…
The design of neural network architectures is frequently either based on human expertise using trial/error and empirical feedback or tackled via large scale reinforcement learning strategies performed over distinct discrete architecture…
Learning discriminative node representations benefits various downstream tasks in graph analysis such as community detection and node classification. Existing graph representation learning methods (e.g., based on random walk and contrastive…
Motif extraction is an important task in motif based molecular representation learning. Previously, machine learning approaches employing either rule-based or string-based techniques to extract motifs. Rule-based approaches may extract…
A time series motif intuitively is a short time series that repeats itself approximately the same within a larger time series. Such motifs often represent concealed structures, such as heart beats in an ECG recording, the riff in a pop…
Pattern matching can be used to calculate the support of patterns, and is a key issue in sequential pattern mining (or sequence pattern mining). Nonoverlapping pattern matching means that two occurrences cannot use the same character in the…
While heterophily has been widely studied in node-level tasks, its impact on graph-level tasks remains unclear. We present the first analysis of heterophily in graph-level learning, combining theoretical insights with empirical validation.…
Causal discovery from observational data is an important tool in many branches of science. Under certain assumptions it allows scientists to explain phenomena, predict, and make decisions. In the large sample limit, sound and complete…
Most text retrievers generate \emph{one} query vector to retrieve relevant documents. Yet, the conditional distribution of relevant documents for the query may be multimodal, e.g., representing different interpretations of the query. We…
Information retrieval aims to find information that meets users' needs from the corpus. Different needs correspond to different IR tasks such as document retrieval, open-domain question answering, retrieval-based dialogue, etc., while they…
Accurate computational identification of DNA methylation is essential for understanding epigenetic regulation. Although deep learning excels in this binary classification task, its "black-box" nature impedes biological insight. We address…
Communication and networking research introduces new protocols and standards with an increasing number of researchers relying on real experiments rather than simulations to evaluate the performance of their new protocols. A number of…