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Main objective of this study is to introduce an expert system-based mHealth application that takes Artificial Intelligence support by considering previously introduced solutions from the literature and employing possible requirements for a…

Human-Computer Interaction · Computer Science 2021-08-23 Ismail Ali Afrah , Utku Kose

It is shown that personalization of web content can be advantageously viewed as a form of partial evaluation --- a technique well known in the programming languages community. The basic idea is to model a recommendation space as a program,…

Information Retrieval · Computer Science 2007-05-23 Naren Ramakrishnan

Accurately estimating personalized treatment effects within a study site (e.g., a hospital) has been challenging due to limited sample size. Furthermore, privacy considerations and lack of resources prevent a site from leveraging…

Machine Learning · Statistics 2022-06-17 Xiaoqing Tan , Chung-Chou H. Chang , Ling Zhou , Lu Tang

Optimization problems with both control variables and environmental variables arise in many fields. This paper introduces a framework of personalized optimization to han- dle such problems. Unlike traditional robust optimization,…

Computation · Statistics 2016-07-07 Shifeng Xiong

Modeling disease progression through multiple stages is critical for clinical decision-making for chronic diseases, e.g., cancer, diabetes, chronic kidney diseases, and so on. Existing approaches often model the disease progression as a…

Machine Learning · Computer Science 2025-03-04 Haoyu Yang , Sanjoy Dey , Pablo Meyer

Research is ongoing all over the world for identifying the barriers and finding effective solutions to accelerate the projection of Precision Medicine (PM) in the healthcare industry. Yet there has not been a valid and practical model to…

Computers and Society · Computer Science 2021-06-01 Nasim Sadat Mosavi , Manuel Filipe Santos

Mobile health studies can leverage longitudinal sensor data from smartphones to guide the application of personalized medical interventions. In this paper, we propose that adoption of an instrumental variable approach for randomized trials…

Randomized controlled trials are the gold standard for evaluating the efficacy of an intervention. However, there is often a trade-off between selecting the most scientifically relevant primary endpoint versus a less relevant, but more…

Methodology · Statistics 2026-01-12 Jack M. Wolf , Joseph S. Koopmeiners , David M. Vock

We consider a general difference-in-differences model in which the treatment variable of interest may be non-binary and its value may change in each period. It is generally difficult to estimate treatment parameters defined with the…

Econometrics · Economics 2023-05-30 Takahide Yanagi

Background: The development of scientific software applications is far from trivial, due to the constant increase in the necessary complexity of these applications, their increasing size, and their need for intensive maintenance and reuse.…

Software Engineering · Computer Science 2020-10-21 Elvira-Maria Arvanitou , Apostolos Ampatzoglou , Alexander Chatzigeorgiou , Jeffrey C. Carver

This paper focuses on developing Pareto-optimal estimation and policy learning to identify the most effective treatment that maximizes the total reward from both short-term and long-term effects, which might conflict with each other. For…

Machine Learning · Computer Science 2024-03-13 Yingrong Wang , Anpeng Wu , Haoxuan Li , Weiming Liu , Qiaowei Miao , Ruoxuan Xiong , Fei Wu , Kun Kuang

Software engineering often no longer involves building systems from scratch, but rather integrating functionality from existing software and components or implementing packaged software. Conventional software engineering comprises a set of…

Software Engineering · Computer Science 2020-12-22 Issam Jebreen , Robert Wellington , Stephen G. MacDonell

Suppose we have a binary treatment used to influence an outcome. Given data from an observational or controlled study, we wish to determine whether or not there exists some subset of observed covariates in which the treatment is more…

Methodology · Statistics 2016-03-22 Alexander R. Luedtke , Mark J. van der Laan

Robot-led physical therapy (PT) offers a promising avenue to enhance the care provided by clinical exercise specialists (ES) and physical and occupational therapists to improve patients' adherence to prescribed exercises outside of a…

Black-box heterogeneous treatment effect (HTE) models are increasingly being used to create personalized policies that assign individuals to their optimal treatments. However, they are difficult to understand, and can be burdensome to…

Machine Learning · Computer Science 2022-08-09 Han Wu , Sarah Tan , Weiwei Li , Mia Garrard , Adam Obeng , Drew Dimmery , Shaun Singh , Hanson Wang , Daniel Jiang , Eytan Bakshy

The randomized controlled trial (RCT) is the gold standard for estimating the average treatment effect (ATE) of a medical intervention but requires 100s-1000s of subjects, making it expensive and difficult to implement. While a cross-over…

Signal Processing · Electrical Eng. & Systems 2023-05-10 Sayeri Lala , Niraj K. Jha

Despite the remarkable advances in cancer diagnosis, treatment, and management that have occurred over the past decade, malignant tumors remain a major public health problem. Further progress in combating cancer may be enabled by…

The broad adoption of Electronic Health Records (EHR) has led to vast amounts of data being accumulated on a patient's history, diagnosis, prescriptions, and lab tests. Advances in recommender technologies have the potential to utilize this…

Information Retrieval · Computer Science 2020-09-01 Suman Bhoi , Lee Mong Li , Wynne Hsu

A central question in many fields of scientific research is to determine how an outcome would be affected by an action, or to measure the effect of an action (a.k.a treatment effect). In recent years, a need for estimating the heterogeneous…

Methodology · Statistics 2021-08-24 Weijia Zhang , Jiuyong Li , Lin Liu

Individuals often respond differently to identical treatments, and characterizing such variability in treatment response is an important aim in the practice of personalized medicine. In this article, we describe a non-parametric accelerated…

Methodology · Statistics 2017-06-22 Nicholas C. Henderson , Thomas A. Louis , Gary L. Rosner , Ravi Varadhan
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