Related papers: Cell development obeys maximum Fisher information
We employ a unified framework for computing the information capacity of biological signaling systems using Fisher Information. By deriving closed-form or easily computable information capacity formulas, we quantify how well different…
Molecular Communication (MC) is an emerging field of research focused on understanding how cells in the human body communicate and exploring potential medical applications. In theoretical analysis, the goal is to investigate cellular…
We study the average asymptotic growth rate of cells in randomly fluctuating environments, with multiple viable phenotypes per environment. We show that any information processing strategy has an asymptotic growth rate, which is the sum of:…
Quantum Fisher information characterizes the phase sensitivity of qubits in the spin-boson model with a finite bandwidth spectrum. In contrast with Markovian reservoirs, the quantum Fisher information will flow from the environments to…
Cell populations invade through a combination of proliferation and motility. Proliferation depends on the internal timing of cell division: how long cells take to complete the cell cycle. This timing varies substantially within (and across)…
Metabolic scaling is one of the most important patterns in biology. Theory explaining the 3/4-power size-scaling of biological metabolic rate does not predict the non-linear scaling observed for smaller life forms. Here we present a new…
All living cells interact dynamically with a constantly changing world. Eukaryotes in particular, evolved radically new ways to sense and react to their environment. These advances enabled new and more complex forms of cellular behavior in…
Here we characterized an information measure for cell polarity that applies to non-motile cells responding to a chemical gradient. The central idea is that polarization represents information about the direction of the gradient. We applied…
Motivated by recent discoveries of microbial communities that transfer electrons across centimeter-length scales, this paper studies the information capacity of bacterial cables via electron transfer, which coexists with molecular…
The genetic material of a eukaryotic cell comprises both nuclear DNA (ncDNA) and mitochondrial DNA (mtDNA). These differ markedly in several aspects but nevertheless must encode proteins that are compatible with one another. Here we…
Molecular communication is an expanding body of research. Recent advances in biology have encouraged using genetically engineered bacteria as the main component in the molecular communication. This has stimulated a new line of research that…
We derive closed-form propagators for any $K$-qubit subsystem of a closed $N$-qubit network with a single conserved excitation. A single transition amplitude simultaneously controls excitation flow between subsystems, the positivity and…
Intracellular transport of DNA carriers is a fundamental step of gene delivery. We present here a theoretical approach to study generically a single virus or DNA particle trafficking in a cell cytoplasm. Cellular trafficking has been…
In order to provide a guaranteed precision and a more accurate judgement about the true value of the Cram\'{e}r-Rao bound and its scaling behavior, an upper bound (equivalently a lower bound on the quantum Fisher information) for precision…
The 21-cm signal from neutral hydrogen in the early universe will provide unprecedented information about the first stars and galaxies. Extracting this information, however, requires accounting for many unknown astrophysical processes.…
Parameter degeneracy in blazar spectral energy distributions (SEDs) is known but rarely quantified. This paper introduces a Fisher Information approach to determine theoretical limits to information extraction in the context of one-zone…
This paper studies the hydrodynamic limit of a stochastic process describing the time evolution of a system with N neurons with mean-field interactions produced both by chemical and by electrical synapses. This system can be informally…
In open quantum systems, we study the quantum Fisher information of acceleration for a uniformly accelerated two-level atom coupled to fluctuating electromagnetic fields in the Minkowski vacuum. With the time evolution, for the initial atom…
It has been observed that the growth of the nucleus and the cytoplasm is coordinated during cell growth, resulting in a nearly constant nuclear-to-cell volume ratio (N/C) throughout the cell cycle. Previous studies have shown that the N/C…
Cell membranes interact with a myriad of curvature-active proteins that control membrane morphology and are responsible for mechanosensation and mechanotransduction. Some of these proteins, such as those containing BAR domains, are curved…