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We generalize the Susceptible-Infected-Removed model for epidemics to take into account generic effects of heterogeneity in the degree of susceptibility to infection in the population. We introduce a single new parameter corresponding to a…

Populations and Evolution · Quantitative Biology 2021-01-27 Jonas Neipel , Jonathan Bauermann , Stefano Bo , Tyler Harmon , Frank Jülicher

The present paper introduces a data-driven framework for describing the time-varying nature of an SIRD model in the context of COVID-19. By embedding a rolling regression in a mixed integer bilevel nonlinear programming problem, our aim is…

Populations and Evolution · Quantitative Biology 2021-03-04 Javier Rubio-Herrero , Yuchen Wang

Human mobility forms the backbone of contact patterns through which infectious diseases propagate, fundamentally shaping the spatio-temporal dynamics of epidemics and pandemics. While traditional models are often based on the assumption…

Accurate stochastic simulations of hourly precipitation are needed for impact studies at local spatial scales. Statistically, hourly precipitation data represent a difficult challenge. They are non-negative, skewed, heavy tailed, contain a…

Methodology · Statistics 2015-06-22 Erwan Koch , Philippe Naveau

Traditional disease transmission models assume that the infectious period is exponentially distributed with a recovery rate fixed in time and across individuals. This assumption provides analytical and computational advantages, however it…

Populations and Evolution · Quantitative Biology 2024-01-30 Laura Di Domenico , Eugenio Valdano , Vittoria Colizza

Contagious processes, such as spread of infectious diseases, social behaviors, or computer viruses, affect biological, social, and technological systems. Epidemic models for large populations and finite populations on networks have been…

Optimization and Control · Mathematics 2020-04-14 Renato Pagliara , Naomi E. Leonard

We develop a mathematical framework to study the economic impact of infectious diseases by integrating epidemiological dynamics with a kinetic model of wealth exchange. The multi-agent description leads to study the evolution over time of a…

Physics and Society · Physics 2020-08-12 G. Dimarco , L. Pareschi , G. Toscani , M. Zanella

The purpose of this study is to leverage modern technology (such as mobile or web apps in Beckman et al. (2014)) to enrich epidemiology data and infer the transmission of disease. Homogeneity related research on population level has been…

Applications · Statistics 2015-09-02 Kai Fan , Allison E. Aiello , Katherine A. Heller

Human behaviour strongly influences the spread of infectious diseases: understanding the interplay between epidemic dynamics and adaptive behaviours is essential to improve response strategies to epidemics, with the goal of containing the…

Physics and Society · Physics 2024-08-21 Marco Mancastroppa , Alessandro Vezzani , Vittoria Colizza , Raffaella Burioni

Since survival data occur over time, often important covariates that we wish to consider also change over time. Such covariates are referred as time-dependent covariates. Quantile regression offers flexible modeling of survival data by…

Methodology · Statistics 2014-05-01 Malka Gorfine , Yair Goldberg , Yaacov Ritov

The global spread of pandemics is facilitated by the mobility of populations, transforming localized infections into widespread phenomena. To contain it, timely identification of influential regions that accelerate this process is…

Signal Processing · Electrical Eng. & Systems 2025-09-15 Sudeepini Darapu , Subrata Ghosh , Dibakar Ghosh , Chittaranjan Hens , Santosh Nannuru

A model describing the dynamics related to the spreading of non-lethal infectious diseases in a fixed-size population is proposed. The model consists of a non-linear delay-differential equation describing the time evolution of the increment…

Populations and Evolution · Quantitative Biology 2010-10-05 A. Noviello , F. Romeo , R. De Luca

Interaction-driven modeling of diseases over real-world contact data has been shown to promote the understanding of the spread of diseases in communities. This temporal modeling follows the path-preserving order and timing of the contacts,…

Applications · Statistics 2023-07-13 Yanir Marmor , Alex Abbey , Yuval Shahar , Osnat Mokryn

Capturing the structured mixing within a population is key to the reliable projection of infectious disease dynamics and hence informed control. Both heterogeneity in the number of contacts and age-structured mixing have been repeatedly…

Social and Information Networks · Computer Science 2026-03-17 Luke Murray Kearney , Emma L Davis , Matt J Keeling

For two-component load-sharing systems, a doubly-flexible model is developed where the generalized Fruend bivariate (GFB) distribution is used for the baseline of the component lifetimes, and the generalized gamma (GG) family of…

Applications · Statistics 2025-09-17 Shilpi Biswas , Ayon Ganguly , Debanjan Mitra

We study the spread of multi-competitive viruses over a (possibly) time-varying network of individuals accounting for the presence of shared infrastructure networks that further enables transmission of the virus. We establish a sufficient…

Systems and Control · Electrical Eng. & Systems 2023-03-17 Sebin Gracy , Yuan Wang , Philip E. Pare , Cesar A Uribe

Network epidemiology has become a core framework for investigating the role of human contact patterns in the spreading of infectious diseases. In network epidemiology represents the contact structure as a network of nodes (individuals)…

Populations and Evolution · Quantitative Biology 2014-06-10 Petter Holme

The spread of viruses in biological networks, computer networks, and human contact networks can have devastating effects; developing and analyzing mathematical models of these systems can be insightful and lead to societal benefits. Prior…

Optimization and Control · Mathematics 2016-09-19 Philip E. Paré , Angelia Nedić , Carolyn L. Beck

Dynamic properties of spreading infection through a heterogeneous population are studied numerically and analytically using a dynamic variant of Watts and Strogatz Small World Network-based stochastic Susceptible-Exposed-Infectious-Removed…

Populations and Evolution · Quantitative Biology 2019-06-28 O. Mosbah , N. Zekri , M. Mokhtari , S. Sahraoui

Reliable estimation of spatio-temporal trends in population-level HIV incidence is becoming an increasingly critical component of HIV prevention policy-making. However, direct measurement is nearly impossible. Current, widely used models…

Applications · Statistics 2019-12-04 Timothy M Wolock , Seth R Flaxman , Jeffrey W Eaton