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X-ray fluorescence computed tomography (XFCT) is a molecular imaging technique of x-ray photons, which can be used to sense different elements or nanoparticle (NP) agents inside deep samples or tissues. XFCT has been an active research…

Medical Physics · Physics 2021-02-01 Ignacio O. Romero , Yile Fang , Michael Lun , Changqing Li

Here we present new joint reconstruction and regularization techniques inspired by ideas in microlocal analysis and lambda tomography, for the simultaneous reconstruction of the attenuation coefficient and electron density from X-ray…

Image and Video Processing · Electrical Eng. & Systems 2020-08-26 James Webber , Eric Todd Quinto , Eric L. Miller

Biophotonics is an active research area in molecular imaging, genetic diagnosis and prognosis, with direct applicability in precision medicine. However, long-standing challenges of biophotonics are well known due to low signal-to-noise…

Medical Physics · Physics 2017-10-02 Michael C Lun , Wei Zhang , Yue Zhao , Jeffrey Anker , Wenxiang Cong , Ge Wang , Changqing Li

X-ray fluorescence computed tomography (XFCT), a form of X-ray molecular imaging, offers detailed quantitative imaging capabilities for high-Z metal nanoparticles (MNPs), which are widely studied for their applications in multifunctional…

Three-dimensional x-ray CT image reconstruction in baggage scanning in security applications is an important research field. The variety of materials to be reconstructed is broader than medical x-ray imaging. Presence of high attenuating…

Computer Vision and Pattern Recognition · Computer Science 2015-08-20 S. Degirmenci , Joseph A. O'Sullivan , David G. Politte

X-ray fluorescence (XRF) enables element-specific, nondestructive imaging, but conventional raster scanning scales poorly with sample size, particularly for tomography, because measurements must be repeated at every projection angle and…

Optics · Physics 2026-04-14 A. Ben-Yehuda , A. Rack , S. Shwartz , N. Viganò

X-ray fluorescence holography (XFH) is a method for obtaining diffraction-limited images of the local atomic structure around a given type of emitter. The reconstructed wave-field represents a distorted image of the scatterer electron…

Condensed Matter · Physics 2009-09-29 S. Marchesini , C. S. Fadley , F. J. Garcia de Abajo

The characterization of nanostructured surfaces with sensitivity in the sub-nm range is of high importance for the development of current and next generation integrated electronic circuits. Modern transistor architectures for e.g. FinFETs…

Due to the merit of establishing volumetric data, X-ray computed tomography (XCT) is increasingly used as a non-destructive evaluation technique in the quality control of advanced manufactured parts with complex non-line-of-sight features.…

X-ray luminescence is produced when contrast agents absorb energy from X-ray photons and release a portion of that energy by emitting photons in the visible and near-infrared range. X-ray luminescence computed tomography (XLCT) was…

Image and Video Processing · Electrical Eng. & Systems 2024-06-13 Yile Fang , Yibing Zhang , Changqing Li

Quantifying material mass and electron density from computed tomography (CT) reconstructions can be highly valuable in certain medical practices, such as radiation therapy planning. However, uniquely parameterising the X-ray attenuation in…

Medical Physics · Physics 2019-04-30 Jonathan H. Mason , Alessandro Perelli , William H. Nailon , Mike E. Davies

Due to the low X-ray photon utilization efficiency and low measurement sensitivity of the electron multiplying charge coupled device (EMCCD) camera setup, the collimator based narrow beam X-ray luminescence computed tomography (XLCT)…

Medical Physics · Physics 2018-03-14 Wei Zhang , Michael C Lun , Alex Anh-Tu Nguyen , Changqing Li

Fluorescence Molecular Tomography (FMT) is a promising technique for non-invasive 3D visualization of fluorescent probes, but its reconstruction remains challenging due to the inherent ill-posedness and reliance on inaccurate or…

Image and Video Processing · Electrical Eng. & Systems 2025-11-07 Shihan Zhao , Jianru Zhang , Yanan Wu , Linlin Li , Siyuan Shen , Xingjun Zhu , Guoyan Zheng , Jiahua Jiang , Wuwei Ren

X-ray computed tomography (XCT) has become a reliable metrology tool for measuring internal flaws and other microstructural features in engineering materials. However, tracking of material points to measure three-dimensional (3D)…

Materials Science · Physics 2023-04-13 Zifan Wang , Akshay Joshi , Angkur Jyoti Dipanka Shaikeea , Vikram Susdhir Deshpande

Limited-angle tomography is a highly ill-posed linear inverse problem. It arises in many applications, such as digital breast tomosynthesis. Reconstructions from limited-angle data typically suffer from severe stretching of features along…

Image and Video Processing · Electrical Eng. & Systems 2022-04-22 Siiri Rautio , Rashmi Murthy , Tatiana A. Bubba , Matti Lassas , Samuli Siltanen

Schemes for X-ray imaging single protein molecules using new x-ray sources, like x-ray free electron lasers (XFELs), require processing many frames of data that are obtained by taking temporally short snapshots of identical molecules, each…

Data Analysis, Statistics and Probability · Physics 2015-06-17 Kartik Ayyer , Hugh T. Philipp , Mark W. Tate , Veit Elser , Sol M. Gruner

While Computerized Tomography (CT) images can help detect disease such as Covid-19, regular CT machines are large and expensive. Cheaper and more portable machines suffer from errors in geometry acquisition that downgrades CT image quality.…

Image and Video Processing · Electrical Eng. & Systems 2021-08-03 Peijian Ding

We propose a new modeling approach for scatter estimation and descattering in polyenergetic X-ray computed tomography (CT) based on fitting models to local neighborhoods of a training set. X-ray CT is widely used in medical and industrial…

Image and Video Processing · Electrical Eng. & Systems 2021-09-30 Michael T. McCann , Marc L. Klasky , Jennifer L. Schei , Saiprasad Ravishankar

Fluorescence molecular tomography (FMT) is an emerging powerful tool for biomedical research. There are two factors that influence FMT reconstruction most effectively. The first one is the regularization techniques. Traditional methods such…

Image and Video Processing · Electrical Eng. & Systems 2021-09-09 Yan Liu , Wuwei Ren , Habib Ammari

X-ray computed tomography (CT) is widely used in medical imaging, with sparse-view reconstruction offering an effective way to reduce radiation dose. However, ill-posed conditions often result in severe streak artifacts. Recent advances in…

Image and Video Processing · Electrical Eng. & Systems 2025-12-30 Jiashu Dong , Jiabing Xiang , Lisheng Geng , Suqing Tian , Wei Zhao
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