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Computational methods have complemented experimental and clinical neursciences and led to improvements in our understanding of the nervous systems in health and disease. In parallel, neuromodulation in form of electric and magnetic…

Neurons and Cognition · Quantitative Biology 2014-08-13 Markus A. Dahlem , Sebastian Rode , Arne May , Naoya Fujiwara , Yoshito Hirata , Kazuyuki Aihara , Jürgen Kurths

This review provides a dynamical systems perspective on psychiatric symptoms and disease, and discusses its potential implications for diagnosis, prognosis, and treatment. After a brief introduction into the theory of dynamical systems, we…

Neurons and Cognition · Quantitative Biology 2018-09-18 Daniel Durstewitz , Quentin J. M. Huys , Georgia Koppe

Migraine (MGR) ranks first among diseases in terms of years of lost healthy life in young adult and adult women. Currently, there is no theory of MGR. This paper presents a complete theory of migraine that explains its etiology, symptoms,…

Neurons and Cognition · Quantitative Biology 2024-08-14 Ari Rappoport

Migraine is a common disabling headache disorder characterized by recurrent episodes sometimes preceded or accompanied by focal neurological symptoms called aura. The relation between two subtypes, migraine without aura (MWoA) and migraine…

Neurons and Cognition · Quantitative Biology 2014-08-13 Markus A. Dahlem

From interacting cellular components to networks of neurons and neural systems, interconnected units comprise a fundamental organizing principle of the nervous system. Understanding how their patterns of connections and interactions give…

Neurons and Cognition · Quantitative Biology 2018-08-01 Danielle S. Bassett , Perry Zurn , Joshua I. Gold

Neurodegenerative diseases are characterized by the accumulation of misfolded proteins and widespread disruptions in brain function. Computational modeling has advanced our understanding of these processes, but efforts have traditionally…

The brain is a complex system comprising a myriad of interacting elements, posing significant challenges in understanding its structure, function, and dynamics. Network science has emerged as a powerful tool for studying such intricate…

A complete understanding of the brain requires an integrated description of the numerous scales of neural organization. It means studying the interplay of genes, synapses, and even whole brain regions which ultimately leads to different…

Neurons and Cognition · Quantitative Biology 2022-08-09 Charley Presigny , Fabrizio De Vico Fallani

The nervous system displays a variety of rhythms in both waking and sleep. These rhythms have been closely associated with different behavioral and cognitive states, but it is still unknown how the nervous system makes use of these rhythms…

Dynamical Systems · Mathematics 2007-05-23 Nancy Kopell

The tools of weakly coupled phase oscillator theory have had a profound impact on the neuroscience community, providing insight into a variety of network behaviours ranging from central pattern generation to synchronisation, as well as…

Adaptation and Self-Organizing Systems · Physics 2016-04-05 Peter Ashwin , Stephen Coombes , Rachel Nicks

Neuroengineering is faced with unique challenges in repairing or replacing complex neural systems that are composed of many interacting parts. These interactions form intricate patterns over large spatiotemporal scales, and produce emergent…

Neurons and Cognition · Quantitative Biology 2016-12-26 Danielle S. Bassett , Ankit N. Khambhati , Scott T. Grafton

Deciphering the underpinnings of the dynamical processes leading to information transmission, processing, and storing in the brain is a crucial challenge in neuroscience. An inspiring but speculative theoretical idea is that such dynamics…

Statistical Mechanics · Physics 2023-07-21 Guillermo B. Morales , Serena Di Santo , Miguel A. Muñoz

Complex functional brain network analyses have exploded over the last eight years, gaining traction due to their profound clinical implications. The application of network science (an interdisciplinary offshoot of graph theory) has…

Methodology · Statistics 2013-10-28 Sean L. Simpson , F. DuBois Bowman , Paul J. Laurienti

Network analyses in nervous system disorders involves constructing and analyzing anatomical and functional brain networks from neuroimaging data to describe and predict the clinical syndromes that result from neuropathology. A network view…

Neurons and Cognition · Quantitative Biology 2017-01-05 John D. Medaglia , Danielle S. Bassett

Math anxiety is a clinical pathology impairing cognitive processing in math-related contexts. Originally thought to affect only inexperienced, low-achieving students, recent investigations show how math anxiety is vastly diffused even among…

Social and Information Networks · Computer Science 2021-09-01 Massimo Stella

The ability to effectively control brain dynamics holds great promise for the enhancement of cognitive function in humans, and the betterment of their quality of life. Yet, successfully controlling dynamics in neural systems is challenging,…

Quantitative Methods · Quantitative Biology 2018-08-29 Evelyn Tang , Danielle S. Bassett

Precision medicine has received attention both in and outside the clinic. We focus on the latter, by exploiting the relationship between individuals' social interactions and their mental health to develop a predictive model of one's…

Social and Information Networks · Computer Science 2019-08-08 Shikang Liu , David Hachen , Omar Lizardo , Christian Poellabauer , Aaron Striegel , Tijana Milenkovic

Network medicine is an emerging area of research dealing with molecular and genetic interactions, network biomarkers of disease, and therapeutic target discovery. Large-scale biomedical data generation offers a unique opportunity to assess…

Molecular Networks · Quantitative Biology 2019-03-14 Abhijeet R. Sonawane , Scott T. Weiss , Kimberly Glass , Amitabh Sharma

Several approaches to cognition and intelligence research rely on statistics-based models testing, namely factor analysis. In the present work we exploit the emerging dynamical systems perspective putting the focus on the role of the…

Physics and Society · Physics 2018-03-15 Gemma Rosell-Tarragó , Emanuele Cozzo , Albert Díaz-Guilera

Neurostimulation technologies have seen a recent surge in interest from the neuroscience and controls communities alike due to their proven potential to treat conditions such as Parkinson's Disease, and depression. The provided stimulation…

Systems and Control · Electrical Eng. & Systems 2023-01-03 Gagan Acharya , Sebastian F. Ruf , Erfan Nozari
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