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Computational identification of promoters is notoriously difficult as human genes often have unique promoter sequences that provide regulation of transcription and interaction with transcription initiation complex. While there are many…

Genomics · Quantitative Biology 2018-10-04 Ramzan Umarov , Hiroyuki Kuwahara , Yu Li , Xin Gao , Victor Solovyev

The detection of induced pluripotent stem cell (iPSC) colonies often needs the precise extraction of the colony features. However, existing computerized systems relied on segmentation of contours by preprocessing for classifying the colony…

Image and Video Processing · Electrical Eng. & Systems 2022-03-10 Novanto Yudistira , Muthu Subash Kavitha , Jeny Rajan , Takio Kurita

Neuroscientists classify neurons into different types that perform similar computations at different locations in the visual field. Traditional methods for neural system identification do not capitalize on this separation of 'what' and…

Machine Learning · Statistics 2018-01-30 David A. Klindt , Alexander S. Ecker , Thomas Euler , Matthias Bethge

Several modern genomic technologies, such as DNA-Methylation arrays, measure spatially registered probes that number in the hundreds of thousands across multiplechromosomes. The measured probes are by themselves less interesting…

Applications · Statistics 2016-11-16 John Nagorski , Genevera I. Allen

In recent years, deep learning models have become ubiquitous in industry and academia alike. Modern deep neural networks can solve one of the most complex problems today, but coming with the price of massive compute and storage…

Distributed, Parallel, and Cluster Computing · Computer Science 2021-10-12 Shreshth Tuli

Splicing sites provide unique statistics in human genome due to their large number and reasonably complete annotation. Analyses of the cumulative SNPs distribution in splicing sites reveal a few interesting observations. While a degree of…

Genomics · Quantitative Biology 2007-05-23 Dmitri Parkhomchuk

The accurate prediction and characterization of DNA melting domains by computational tools could facilitate a broad range of biological applications. However, no algorithm for melting domain prediction has been available until now. The main…

Biomolecules · Quantitative Biology 2008-12-17 Eivind Tøstesen , Geir Kjetil Sandve , Fang Liu , Eivind Hovig

Determining the localization of specific protein in human cells is important for understanding cellular functions and biological processes of underlying diseases. Among imaging techniques, high-throughput fluorescence microscopy imaging is…

Computer Vision and Pattern Recognition · Computer Science 2019-02-01 Yijun Tian

The increasing data rates in modern high-energy physics experiments such as ALICE at the LHC and the upcoming ePIC experiment at the Electron-Ion Collider (EIC) present significant challenges in real-time event selection and data storage.…

High Energy Physics - Experiment · Physics 2025-06-24 Simone Ragoni , Janet Seger , Christopher Anson , David Tlusty

This work introduces a new problem, named as, affinity classification problem which is a generalization of the density classification problem. To solve this problem, we introduce temporally stochastic cellular automata where two rules are…

Formal Languages and Automata Theory · Computer Science 2022-07-13 Kamalika Bhattacharjee , Subrata Paul , Sukanta Das

This paper explores the application of Human-in-the-Loop (HITL) strategies in training machine learning models in the medical domain. In this case a doctor-in-the-loop approach is proposed to leverage human expertise in dealing with large…

Computer Vision and Pattern Recognition · Computer Science 2024-04-01 David Vázquez-Lema , Eduardo Mosqueira-Rey , Elena Hernández-Pereira , Carlos Fernández-Lozano , Fernando Seara-Romera , Jorge Pombo-Otero

Continual Learning (CL) is crucial for enabling networks to dynamically adapt as they learn new tasks sequentially, accommodating new data and classes without catastrophic forgetting. Diverging from conventional perspectives on CL, our…

Image and Video Processing · Electrical Eng. & Systems 2024-07-12 Nourhan Bayasi , Jamil Fayyad , Alceu Bissoto , Ghassan Hamarneh , Rafeef Garbi

Predicting ATP-Protein Binding sites in genes is of great significance in the field of Biology and Medicine. The majority of research in this field has been conducted through time- and resource-intensive 'wet experiments' in laboratories.…

Biomolecules · Quantitative Biology 2024-02-06 Shreyas V , Swati Agarwal

Deep learning requires large amounts of training data to be effective. For the task of object segmentation, manually labeling data is very expensive, and hence interactive methods are needed. Following recent approaches, we develop an…

Computer Vision and Pattern Recognition · Computer Science 2018-05-14 Sabarinath Mahadevan , Paul Voigtlaender , Bastian Leibe

Machine learning algorithms often produce models considered as complex black-box models by both end users and developers. They fail to explain the model in terms of the domain they are designed for. The proposed Iterative Visual Logical…

Machine Learning · Computer Science 2021-07-13 Sridevi Narayana Wagle , Boris Kovalerchuk

We study the problem of efficiently estimating counts for queries involving complex filters, such as user-defined functions, or predicates involving self-joins and correlated subqueries. For such queries, traditional sampling techniques may…

Databases · Computer Science 2020-01-01 Brett Walenz , Stavros Sintos , Sudeepa Roy , Jun Yang

Our goal is to bridge human and machine intelligence in melanoma detection. We develop a classification system exploiting a combination of visual pre-processing, deep learning, and ensembling for providing explanations to experts and to…

Computer Vision and Pattern Recognition · Computer Science 2021-03-10 Ellák Somfai , Benjámin Baffy , Kristian Fenech , Changlu Guo , Rita Hosszú , Dorina Korózs , Fabrizio Nunnari , Marcell Pólik , Daniel Sonntag , Attila Ulbert , András Lőrincz

Predicting students' academic performance has been a research area of interest in recent years with many institutions focusing on improving the students' performance and the education quality. The analysis and prediction of students'…

Computers and Society · Computer Science 2020-06-11 MohammadNoor Injadat , Abdallah Moubayed , Ali Bou Nassif , Abdallah Shami

In recent years, Spiking Neural Networks (SNNs) have gathered significant interest due to their temporal understanding capabilities. This work introduces, to the best of our knowledge, the first Cortical Column like hybrid architecture for…

Computer Vision and Pattern Recognition · Computer Science 2024-12-03 Aaron Bateni

Diagnosis and risk stratification of cancer and many other diseases require the detection of genomic breakpoints as a prerequisite of calling copy number alterations (CNA). This, however, is still challenging and requires time-consuming…