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Molecular dynamics (MD) is a powerful tool for exploring the behavior of atomistic systems, but its reliance on sequential numerical integration limits simulation efficiency. We present a novel neural network architecture, MDtrajNet, and a…

Chemical Physics · Physics 2026-03-17 Fuchun Ge , Yuxinxin Chen , Pavlo O. Dral

In recent times, the trend in very large scale integration (VLSI) industry is multi-dimensional, for example, reduction of energy consumption, occupancy of less space, precise result, less power dissipation, faster response. To meet these…

Machine Learning · Computer Science 2021-07-02 Gaurab Bhattacharya

Diffusion-weighted magnetic resonance imaging (DW-MRI) is used to characterize brain tissue microstructure employing tissue-specific biophysical models. A current limitation, however, is that most of the proposed models are based on the…

The structure of proteins is the basis for studying protein function and drug design. The emergence of AlphaFold 2 has greatly promoted the prediction of protein 3D structures, and it is of great significance to give an overall and accurate…

Biomolecules · Quantitative Biology 2024-07-02 Wenda Wang , Jiaqi Zhai , He Huang , Xinqi Gong

Large-scale first principles molecular dynamics are crucial for simulating complex processes in chemical, biomedical, and materials sciences. However, the unfavorable time complexity with respect to system sizes leads to prohibitive…

Distributed quantum computing (DQC) provides a way to scale quantum computers using multiple quantum processing units (QPU) connected through quantum communication links. In this paper, we have built a distributed quantum computing…

Quantum Physics · Physics 2025-03-26 Sreraman Muralidharan

Scalable distributed quantum computing (DQC) has motivated the design of multiple quantum data-center (QDC) architectures that overcome the limitations of single quantum processors through modular interconnection. While these architectures…

Design considerations for molecular dynamics algorithms capable of taking advantage of the computational power of a graphics processing unit (GPU) are described. Accommodating the constraints of scalable streaming-multiprocessor hardware…

Computational Physics · Physics 2011-01-27 D. C. Rapaport

Molecular dynamics (MD) simulations are a central tool in science and engineering enabling the study of dynamical behavior and the link between microscopic structure and macroscopic function. Their high computational cost, however, has…

Chemical Physics · Physics 2026-01-22 Salman N. Salman , Sergey A. Shteingolts , Ron Levie , Dan Mendels

Noise fundamentally limits the performance and predictive capabilities of classical and quantum dynamical systems by degrading stability and obscuring intrinsic dynamical characteristics. Characterizing such noise accurately is essential…

Quantum Physics · Physics 2025-08-07 Adva Baratz , Loris Maria Cangemi , Assaf Hamo , Sivan Refaely-Abramson , Amikam Levy

With the ever-increasing computational demand of DNN training workloads, distributed training has been widely adopted. A combination of data, model and pipeline parallelism strategy, called hybrid parallelism distributed training, is…

Distributed, Parallel, and Cluster Computing · Computer Science 2023-06-16 Guandong Lu , Runzhe Chen , Yakai Wang , Yangjie Zhou , Rui Zhang , Zheng Hu , Yanming Miao , Zhifang Cai , Li Li , Jingwen Leng , Minyi Guo

Molecular motor proteins form the basis of cellular dynamics. Recently, notable efforts have led to the creation of their DNA-based mimics, which can carry out complex nanoscale motion. However, such functional analogues have not yet been…

Biological Physics · Physics 2021-05-14 Kerstin Goepfrich , Maximilian J. Urban , Christoph Frey , Ilia Platzman , Joachim P. Spatz , Na Liu

Large-scale AI model training divides work across thousands of GPUs, then synchronizes gradients across them at each step. This incurs a significant network burden that only centralized, monolithic clusters can support, driving up…

Computer Vision and Pattern Recognition · Computer Science 2025-01-13 David McAllister , Matthew Tancik , Jiaming Song , Angjoo Kanazawa

Advanced manufacturing (AM) technologies, such as nanoscale additive manufacturing process, enable the fabrication of nanoscale architected materials which has received great attention due to their prominent properties. However, few studies…

Applied Physics · Physics 2021-04-08 Rui Dai , Dawei Li , Yunlong Tang

Molecular dynamics simulations are a powerful tool to study diffusion processes in battery electrolyte and electrode materials. From a single molecular dynamics simulation many properties relevant to diffusion can be obtained, including the…

Chemical Physics · Physics 2018-07-09 Niek J. J. de Klerk , Eveline van der Maas , Marnix Wagemaker

Simulation of reasonable timescales for any long physical process using molecular dynamics (MD) is a major challenge in computational physics. In this study, we have implemented an approach based on multi-fidelity physics informed neural…

Computational Physics · Physics 2020-12-08 Mahmudul Islam , Md Shajedul Hoque Thakur , Satyajit Mojumder , Mohammad Nasim Hasan

We present a novel reduced-order fluid simulation technique leveraging Dynamic Mode Decomposition (DMD) to achieve fast, memory-efficient, and user-controllable subspace simulation. We demonstrate that our approach combines the strengths of…

We present a hybrid continuum-atomistic scheme which combines molecular dynamics (MD) simulations with on-the-fly machine learning techniques for the accurate and efficient prediction of multiscale fluidic systems. By using a Gaussian…

Fluid Dynamics · Physics 2016-03-16 David Stephenson , James R Kermode , Duncan A Lockerby

Simulating electrified metal/water interfaces with explicit solvent under constant potential is essential for understanding electrochemical processes, yet remains prohibitively expensive with ab initio methods. We present TRECI, a…

Parallelism of tight-binding molecular dynamics simulations is presented by means of the order-N electronic structure theory with the Wannier states, recently developed (J. Phys. Soc. Jpn. 69,3773 (2000)). An application is tested for…

Materials Science · Physics 2009-11-10 Masaaki Geshi , Takeo Hoshi , Takeo Fujiwara
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