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Due to the scarcity of quantitative details about biological phenomena, quantitative modeling in systems biology can be compromised, especially at the subcellular scale. One way to get around this is qualitative modeling because it requires…

Molecular Networks · Quantitative Biology 2019-03-22 Arnaud Poret , Claudio Monteiro Sousa , Jean-Pierre Boissel

Boolean networks are a popular modeling framework in computational biology to capture the dynamics of molecular networks, such as gene regulatory networks. It has been observed that many published models of such networks are defined by…

Molecular Networks · Quantitative Biology 2019-12-06 Elijah Paul , Gleb Pogudin , William Qin , Reinhard Laubenbacher

We study how to detect groups in a complex network each of which consists of component nodes sharing a similar connection pattern. Based on the mixture models and the exploratory analysis set up by Newman and Leicht (Newman and Leicht 2007…

Data Analysis, Statistics and Probability · Physics 2008-12-17 J. Wang , C. -H. Lai

Models of biochemical networks are frequently high-dimensional and complex. Reduction methods that preserve important dynamical properties are therefore essential in their study. Interactions between the nodes in such networks are…

Molecular Networks · Quantitative Biology 2013-08-23 Alan Veliz-Cuba , Ajit Kumar , Kresimir Josic

Deep learning is computationally intensive, with significant efforts focused on reducing arithmetic complexity, particularly regarding energy consumption dominated by data movement. While existing literature emphasizes inference, training…

Machine Learning · Statistics 2025-06-09 Van Minh Nguyen , Cristian Ocampo , Aymen Askri , Louis Leconte , Ba-Hien Tran

Understanding structural controllability of a complex network requires to identify a Minimum Input nodes Set (MIS) of the network. It has been suggested that finding an MIS is equivalent to computing a maximum matching of the network, where…

Discrete Mathematics · Computer Science 2022-06-02 Xizhe Zhang , Jianfei Han , Weixiong Zhang

We present dichotomy theorems regarding the computational complexity of counting fixed points in boolean (discrete) dynamical systems, i.e., finite discrete dynamical systems over the domain {0,1}. For a class F of boolean functions and a…

Computational Complexity · Computer Science 2008-12-02 Christopher M. Homan , Sven Kosub

We study the problem of change point localization in dynamic networks models. We assume that we observe a sequence of independent adjacency matrices of the same size, each corresponding to a realization of an unknown inhomogeneous Bernoulli…

Methodology · Statistics 2020-10-22 Daren Wang , Yi Yu , Alessandro Rinaldo

Recent machine learning algorithms dedicated to solving semi-linear PDEs are improved by using different neural network architectures and different parameterizations. These algorithms are compared to a new one that solves a fixed point…

Machine Learning · Computer Science 2018-12-11 Quentin Chan-Wai-Nam , Joseph Mikael , Xavier Warin

Botnets are now a major source for many network attacks, such as DDoS attacks and spam. However, most traditional detection methods heavily rely on heuristically designed multi-stage detection criteria. In this paper, we consider the neural…

Cryptography and Security · Computer Science 2020-03-16 Jiawei Zhou , Zhiying Xu , Alexander M. Rush , Minlan Yu

Point sets matching method is very important in computer vision, feature extraction, fingerprint matching, motion estimation and so on. This paper proposes a robust point sets matching method. We present an iterative algorithm that is…

Computer Vision and Pattern Recognition · Computer Science 2014-11-05 Xiao Liu , Congying Han , Tiande Guo

Estimating influential nodes in large scale networks including but not limited to social networks, biological networks, communication networks, emerging smart grids etc. is a topic of fundamental interest. To understand influences of nodes…

Social and Information Networks · Computer Science 2014-06-13 Sima Das

Random boolean networks are a model of genetic regulatory networks that has proven able to describe experimental data in biology. They not only reproduce important phenomena in cell dynamics, but they are also extremely interesting from a…

Dynamical Systems · Mathematics 2015-02-26 Marco Villani , Davide Campioli , Chiara Damiani , Andrea Roli , Alessandro Filisetti , Roberto Serra

Our work presents a new iterative scheme to approximate the fixed points of nonexpansive mapping. The proposed algorithm is constructed to enhance convergence efficiency while preserving theoretical robustness. Under appropriate assumptions…

Functional Analysis · Mathematics 2026-01-12 Nida Izhar Mallick , Izhar Uddin

We develop a data-driven machine learning approach to identifying parameters with steady-state solutions, locating such solutions, and determining their linear stability for systems of ordinary differential equations and dynamical systems…

Numerical Analysis · Mathematics 2025-03-11 Yimeng Zhang , Alexander Cloninger , Bo Li , Xiaochuan Tian

We consider the problem of detecting multiple changepoints in large data sets. Our focus is on applications where the number of changepoints will increase as we collect more data: for example in genetics as we analyse larger regions of the…

Methodology · Statistics 2015-03-17 R. Killick , P. Fearnhead , I. A. Eckley

When analyzing complex networks a key target is to uncover their modular structure, which means searching for a family of modules, namely node subsets spanning each a subnetwork more densely connected than the average. This work proposes a…

Discrete Mathematics · Computer Science 2018-09-10 Giovanni Rossi

We consider the offline change point detection and localization problem in the context of piecewise stationary networks, where the observable is a finite sequence of networks. We develop algorithms involving some suitably modified CUSUM…

Identifying dynamically influential nodes in biological networks is a central problem in systems biology, particularly for prioritizing intervention targets in gene regulatory networks. In this paper, we propose a Shapley-value-based…

Molecular Networks · Quantitative Biology 2026-04-13 Giang Pham , Silvia Giulia Galfrè , Paolo Milazzo

We consider the classic problem of Network Reliability. A network is given together with a source vertex, one or more target vertices, and probabilities assigned to each of the edges. Each edge appears in the network with its associated…

Combinatorics · Mathematics 2019-03-20 Amir Kafshdar Goharshady , Fatemeh Mohammadi