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Repetitive DNA (repeats) poses significant challenges for accurate and efficient genome assembly and sequence alignment. This is particularly true for metagenomic data, where genome dynamics such as horizontal gene transfer, gene…

Machine Learning · Computer Science 2024-02-15 Ali Azizpour , Advait Balaji , Todd J. Treangen , Santiago Segarra

Genomic signal processing has been used successfully in bioinformatics to analyze biomolecular sequences and gain varied insights into DNA structure, gene organization, protein binding, sequence evolution, etc. But challenges remain in…

Genomics · Quantitative Biology 2022-11-04 Saish Jaiswal , Shreya Nema , Hema A Murthy , Manikandan Narayanan

DNA sequencing has faced a huge demand since it was first introduced as a service to the public. This service is often offloaded to the sequencing companies who will have access to full knowledge of individuals' sequences, a major violation…

Information Theory · Computer Science 2019-04-04 Ali Gholami , Mohammad Ali Maddah-Ali , Seyed Abolfazl Motahari

Schur complement matrices emerge in many domain decomposition methods that can solve complex engineering problems using supercomputers. Today, as most of the high-performance clusters' performance lies in GPUs, these methods should also be…

Distributed, Parallel, and Cluster Computing · Computer Science 2025-09-26 Jakub Homola , Ondřej Meca , Lubomír Říha , Tomáš Brzobohatý

Phase retrieval, a nonlinear problem prevalent in imaging applications, has been extensively studied using random models, some of which with i.i.d. sensing matrix components. While these models offer robust reconstruction guarantees, they…

Optics · Physics 2024-09-10 Zhiyuan Hu , Julián Tachella , Michael Unser , Jonathan Dong

FPGA is appropriate for fix-point neural networks computing due to high power efficiency and configurability. However, its design must be intensively refined to achieve high performance using limited hardware resources. We present an…

Hardware Architecture · Computer Science 2022-01-03 Qingyang Yi , Heming Sun , Masahiro Fujita

Matrix-accelerated stencil computation is a hot research topic, yet its application to three-dimensional (3D) high-order stencils and HPC remains underexplored. With the emergence of matrix units on multicore CPUs, we analyze matrix-based…

Distributed, Parallel, and Cluster Computing · Computer Science 2025-07-16 Yinuo Wang , Tianqi Mao , Lin Gan , Wubing Wan , Zeyu Song , Jiayu Fu , Lanke He , Wenqiang Wang , Zekun Yin , Wei Xue , Guangwen Yang

Image segmentation plays an important role in computer vision, object detection, traffic control, and video surveillance. Typically, it is a critical step in the 3D reconstruction of a specific organ in medical image processing which…

Image and Video Processing · Electrical Eng. & Systems 2020-12-22 Yu-Wei Chang , Tony W. H. Sheu

DNA sequences are prone to creating secondary structures by folding back on themselves by non-specific hybridization among its nucleotides. The formation of secondary structures makes the sequences chemically inactive towards synthesis and…

Information Theory · Computer Science 2022-11-30 Siddhartha Siddhiprada Bhoi , Paramapalli Udaya , Abhay Kumar Singh

Range minimum queries are frequently used in string processing and database applications including biological sequence analysis, document retrieval, and web search. Hence, various data structures have been proposed for improving their…

Databases · Computer Science 2026-04-03 Lara Kreis , Justus Henneberg , Valentin Henkys , Felix Schuhknecht , Bertil Schmidt

Convolutional neural network (CNN) is an important deep learning method. The convolution operation takes a large proportion of the total execution time for CNN. Feature maps for convolution operation are usually sparse. Multiplications and…

Distributed, Parallel, and Cluster Computing · Computer Science 2023-08-01 Weizhi Xu , Yintai Sun , fhengyu Fan , Hui Yu , Xin Fu

DNA pattern matching is essential for many widely used bioinformatics applications. Disease diagnosis is one of these applications, since analyzing changes in DNA sequences can increase our understanding of possible genetic diseases. The…

Hardware Architecture · Computer Science 2022-06-01 Jinane Bazzi , Jana Sweidan , Mohammed E. Fouda , Rouwaida Kanj , Ahmed M. Eltawil

Fourier Ptychographic Microscopy (FPM) is a computational imaging technique that enables high-resolution imaging over a large field of view. However, its application in the biomedical field has been limited due to the long image…

Image and Video Processing · Electrical Eng. & Systems 2024-08-27 Ruiqing Sun , Delong Yang , Yiyan Su , Shaohui Zhang , Qun Hao

Ptychography is an emerging imaging technique that is able to provide wavelength-limited spatial resolution from specimen with extended lateral dimensions. As a scanning microscopy method, a typical two-dimensional image requires a number…

We investigate GPU-based parallelization of Iterative-Deepening A* (IDA*). We show that straightforward thread-based parallelization techniques which were previously proposed for massively parallel SIMD processors perform poorly due to warp…

Artificial Intelligence · Computer Science 2017-05-09 Satoru Horie , Alex Fukunaga

Synthesis of DNA molecules offers unprecedented advances in storage technology. Yet, the microscopic world in which these molecules reside induces error patterns that are fundamentally different from their digital counterparts. Hence, to…

Information Theory · Computer Science 2017-08-08 Netanel Raviv , Moshe Schwartz , Eitan Yaakobi

We present a new implementation of the Floyd-Warshall All-Pairs Shortest Paths algorithm on CUDA. Our algorithm runs approximately 5 times faster than the previously best reported algorithm. In order to achieve this speedup, we applied a…

Distributed, Parallel, and Cluster Computing · Computer Science 2010-02-25 Ben Lund , Justin W Smith

Sequence alignment is a cornerstone of bioinformatics, widely used to identify similarities between DNA, RNA, and protein sequences and studying evolutionary relationships and functional properties. The Needleman-Wunsch algorithm remains a…

Distributed, Parallel, and Cluster Computing · Computer Science 2024-12-31 Linus Zwaka

This paper explores convolutional generative networks as an alternative to iterative reconstruction algorithms in medical image reconstruction. The task of medical image reconstruction involves mapping of projection main data collected from…

Medical Physics · Physics 2020-12-04 V. S. S. Kandarpa , Alexandre Bousse , Didier Benoit , Dimitris Visvikis

The increasing scale and complexity of integrated circuit design have led to increased challenges in Electronic Design Automation (EDA). Graph Neural Networks (GNNs) have emerged as a promising approach to assist EDA design as circuits can…

Machine Learning · Computer Science 2025-08-26 Yuebo Luo , Shiyang Li , Junran Tao , Kiran Thorat , Xi Xie , Hongwu Peng , Nuo Xu , Caiwen Ding , Shaoyi Huang