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How can dense biological tissue maintain sharp boundaries between coexisting cell populations? We explore this question within a simple vertex model for cells, focusing on the role of topology and tissue surface tension. We show that the…

Soft Condensed Matter · Physics 2018-02-07 Daniel M. Sussman , J. M. Schwarz , M. Cristina Marchetti , M. Lisa Manning

Characterizing the softness of deformable materials having partial elastic and partial viscous behaviour via soft lubrication experiments has emerged as a versatile and robust methodology in recent times. However, a straightforward…

Soft Condensed Matter · Physics 2021-07-22 Pratyaksh Karan , Jeevanjyoti Chakraborty , Suman Chakraborty

The properties of polymer liquids on hard and soft substrates are investigated by molecular dynamics simulation of a coarse-grained bead-spring model and dynamic single-chain-in-mean-field (SCMF) simulations of a soft, coarse-grained…

Soft Condensed Matter · Physics 2015-05-18 F. Léonforte , J. Servantie , C. Pastorino , M. Müller

The mechanical response of cellular materials with spinodal topologies is numerically and experimentally investigated. Spinodal microstructures are generated by the numerical solution of the Cahn-Hilliard equation. Two different topologies…

Materials Science · Physics 2019-04-16 Meng-Ting Hsieh , Bianca Endo , Yunfei Zhang , Jens Bauer , Lorenzo Valdevit

Soft particles such as microgels and core-shell particles can undergo significant and anisotropic deformations when adsorbed to a liquid interface. This, in turn, leads to a complex phase behavior upon compression. Here we develop a…

Lipid membranes, the barrier defining living cells and many of their sub-compartments, bind to a wide variety of nano- and micro-meter sized objects. In the presence of strong adhesive forces, membranes can strongly deform and wrap the…

Cell-cell adhesion is one the most fundamental mechanisms regulating collective cell migration during tissue development, homeostasis and repair, allowing cell populations to self-organize and eventually form and maintain complex tissue…

Cell Behavior · Quantitative Biology 2022-11-16 Carles Falcó , Ruth E. Baker , José A. Carrillo

Biot's theory predicts the wave velocities of a saturated poroelastic granular medium from the elastic properties, density and geometry of its dry solid matrix and the pore fluid, neglecting the interaction between constituent particles and…

Geophysics · Physics 2019-05-01 Hongyang Cheng , Stefan Luding , Nicolás Rivas , Jens Harting , Vanessa Magnanimo

This study proposes and explores a linear hydrodynamic thermo-elasticity system within mixture models, comprising fluid and solid phases, with a focus on biological tissues, particularly tumor-related phenomena. Although tumor growth is not…

Analysis of PDEs · Mathematics 2025-02-11 Michael Eden , Meraj Alam , Prakash Kumar , G P Raja Sekhar

Chemical thermodynamic models of solvent and solute activities predict the equilibrium behaviour of aqueous solutions. How-ever, these models are semi-empirical. They represent micro-scale ion and solvent behaviours that control the…

Chemical Physics · Physics 2022-01-26 Xiangwen Wang , Simon L. Clegg , Devis Di Tommaso

The present work demonstrates a robust protocol for probing localized electronic structure in condensed-phase systems, operating in terms of a recently proposed theory for decomposing the results of Kohn-Sham density functional theory in a…

Chemical Physics · Physics 2021-06-29 Janus J. Eriksen

Wet granular materials in a quasi-static steady state shear flow have been studied with discrete particle simulations. Macroscopic quantities, consistent with the conservation laws of continuum theory, are obtained by time averaging and…

Soft Condensed Matter · Physics 2015-06-23 Sudeshna Roy , Abhinendra Singh , Stefan Luding , Thomas Weinhart

In this paper we address some modelling issues related to biological growth. Our treatment is based on a recently-proposed, general formulation for growth within the context of Mixture Theory (Journal of the Mechanics and Physics of Solids,…

Tissues and Organs · Quantitative Biology 2011-11-09 H. Narayanan , E. M. Arruda , K. Grosh , K. Garikipati

Thermoresponsive microgels are polymeric colloidal networks that can change their size in response to a temperature variation. This peculiar feature is driven by the nature of the solvent-polymer interactions, which triggers the so-called…

Soft Condensed Matter · Physics 2019-02-08 Fabrizio Camerin , Nicoletta Gnan , Lorenzo Rovigatti , Emanuela Zaccarelli

Gels in soft-matter systems are an important nonergodic state of matter. We study a colloid-polymer mixture which is quenched by increasing the polymer concentration, from a fluid to a gel. Using confocal microscopy, we study both the…

Soft Condensed Matter · Physics 2009-04-20 Takehiro Ohtsuka , C. Patrick Royall , Hajime Tanaka

The deformability of soft condensed matter often requires modelling of hydrodynamical aspects to gain quantitative understanding. This, however, requires specialised methods that can resolve the multiscale nature of soft matter systems. We…

Soft Condensed Matter · Physics 2017-12-22 Ulf D. Schiller , Timm Krüger , Oliver Henrich

We study swelling and structural properties of ionic microgel suspensions within a comprehensive coarse-grained model that combines the polymeric and colloidal natures of microgels as permeable, compressible, charged spheres governed by…

Soft Condensed Matter · Physics 2018-06-07 Tyler J. Weyer , Alan R. Denton

Using molecular dynamic simulations we study a waterlike model confined between two fixed hydrophobic plates. The system is tested for density, diffusion and structural anomalous behavior and compared with the bulk results. Within the range…

Chemical Physics · Physics 2013-03-06 Leandro Batirolla Krott , Marcia Cristina Bernardes Barbosa

Colloidal particles that are confined to an interface such as the air-water interface are an example of a two-dimensional fluid. Such dispersions have been observed to spontaneously form cluster and stripe morphologies in certain systems…

Soft Condensed Matter · Physics 2008-09-17 A. J. Archer

We have studied by Molecular Dynamics computer simulations the dynamics of water confined in ionic surfactants phases, ranging from well ordered lamellar structures to micelles at low and high water loading, respectively. We have analysed…

Soft Condensed Matter · Physics 2016-03-23 Samuel Hanot , Sandrine Lyonnard , Stefano Mossa