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The effect of intrinsic channel noise is investigated for the dynamic response of a neuronal cell with a delayed feedback loop. The loop is based on the so-called autapse phenomenon in which dendrites establish not only connections to…

Biological Physics · Physics 2014-12-22 Yunyun Li , Gerhard Schmid , Peter Hanggi , Lutz Schimansky-Geier

The classic Hodgkin-Huxley model is widely used for understanding the electrophysiological dynamics of a single neuron. While applying a constant current to the system results in a single voltage spike, it is possible to produce more…

Quantitative Methods · Quantitative Biology 2021-07-23 Kayleigh Campbell , Laura Staugler , Andrea Arnold

Hodgkin-Huxley equations as a monumental breakthrough in biological and physiological theory of the 20th century had been distilled into many simplified models to study, typically FitzHugh-Nagumo equations and Hindmarsh-Rose equations, but…

Analysis of PDEs · Mathematics 2026-05-11 Yuncheng You

A novel approach to moment closure problem is used to derive low dimensional laws for the dynamics of the moments of the membrane potential distribution in a population of spiking neurons. Using spectral expansion of the density equation we…

Statistical Mechanics · Physics 2025-07-08 Gianni Valerio Vinci , Roberto Benzi , Maurizio Mattia

We investigate dynamical heterogeneities in the collective relaxation of a concentrated microgel system, for which the packing fraction can be conveniently varied by changing the temperature. The packing fraction dependent mechanical…

Soft Condensed Matter · Physics 2011-05-31 David A. Sessoms , Irmgard Bischofberger , Luca Cipelletti , Véronique Trappe

A ferrofluid droplet confined in a Hele-Shaw cell can be deformed into a stably spinning ``gear,'' using crossed magnetic fields. Previously, fully nonlinear simulation revealed that the spinning gear emerges as a stable traveling wave…

Pattern Formation and Solitons · Physics 2023-05-19 Zongxin Yu , Ivan C. Christov

Serotonergic, noradrenergic and dopaminergic brainstem (including midbrain) neurons, often exhibit spontaneous and fairly regular spiking with frequencies of order a few Hz, though dopaminergic and noradrenergic neurons only exhibit such…

Neurons and Cognition · Quantitative Biology 2017-04-18 Henry C. Tuckwell , Ying Zhou , Nicholas J. Penington

The spiking properties of a subcritical Hopf oscillator with a time delayed nonlinear feedback is investigated. Finite time delay is found to significantly affect both the statistics and the fine structure of the spiking behavior. These…

Chaotic Dynamics · Physics 2009-11-11 Gautam C Sethia , Abhijit Sen

Using a stochastic generalization of the Hodgkin–Huxley model, we consider the influence of intrinsic channel noise on the synchronization between the spiking activity of the excitable membrane and an externally applied periodic…

Biological Physics · Physics 2007-05-23 Gerhard Schmid , Igor Goychuk , Peter Hanggi

We study the dynamics of three-dimensional weakly linked Bose-Einstein condensates using a multimode model with an effective interaction parameter. The system is confined by a ring-shaped four-well trapping potential. By constructing a…

Quantum Gases · Physics 2018-02-27 M. Nigro , P. Capuzzi , H. M. Cataldo , D. M. Jezek

The dynamics of a model, originally proposed for a type of instability in plastic flow, has been investigated in detail. The bifurcation portrait of the system in two physically relevant parameters exhibits a rich variety of dynamical…

Chaotic Dynamics · Physics 2009-10-31 S. Rajesh , G. Ananthakrishna

In this work, we study the dynamics of a spatially heterogeneous single population model with the memory effect and nonlinear boundary condition. By virtue of the implicit function theorem and Lyapunov-Schmidt reduction, spatially…

Dynamical Systems · Mathematics 2024-03-25 Quanli Ji , Ranchao Wu , Tonghua Zhang

We consider Hodgkin-Huxley-type model that is a stiff ODE system with two fast and one slow variables. For the parameter ranges under consideration the original version of the model has unstable fixed point and the oscillating attractor…

Pattern Formation and Solitons · Physics 2023-01-04 Pavel V. Kuptsov , Nataliya V. Stankevich , Elmira R. Bagautdinova

Neuronal models based on the Hodgkin-Huxley equation form a fundamental framework in the field of computational neuroscience. While the neuronal state is often modeled deterministically, experimental recordings show stochastic fluctuations,…

Neurons and Cognition · Quantitative Biology 2018-10-26 Pavol Bauer , Stefan Engblom , Sanja Mikulovic , Aleksandar Senek

The Hodgkin-Huxley model describes the conduction of the nervous impulse through the axon, whose membrane's electric response can be described employing multiple connected electric circuits containing capacitors, voltage sources, and…

Neurons and Cognition · Quantitative Biology 2021-12-13 Tasio Gonzalez-Raya , Enrique Solano , Mikel Sanz

We disclose the generality of the intrinsic mechanisms underlying multistability in reciprocally inhibitory 3-cell circuits composed of simplified, low-dimensional models of oscillatory neurons, as opposed to those of a detailed Hodgkin-…

Adaptation and Self-Organizing Systems · Physics 2020-08-26 J. Collens , K. Pusuluri , A. Kelly , D. Knapper , T. Xing , S. Basodi , D. Alacam , A. L. Shilnikov

Spectral properties of the Hamiltonian function which characterizes a trapped ion are investigated. In order to study semiclassical dynamics of trapped ions, coherent state orbits are introduced as sub-manifolds of the quantum state space,…

Quantum Physics · Physics 2023-02-28 Bogdan M. Mihalcea

Numerical investigations have been made of responses of a Hodgkin-Huxley (HH) neuron to spike-train inputs whose interspike interval (ISI) is modulated by deterministic, semi-deterministic (chaotic) and stochastic signals. As deterministic…

Disordered Systems and Neural Networks · Physics 2009-10-31 Hideo Hasegawa

We present simulations of stochastic fluid dynamics in the vicinity of a critical endpoint belonging to the universality class of the Ising model. This study is motivated by the challenge of modeling the dynamics of critical fluctuations…

Nuclear Theory · Physics 2024-07-23 Chandrodoy Chattopadhyay , Josh Ott , Thomas Schaefer , Vladimir V. Skokov

Neuronal cells present periodic trains of localized voltage spikes involving a large amount of different ionic channels. A relevant question is whether this is a cooperative effect or it could also be an intrinsic property of individual…

Biological Physics · Physics 2018-04-17 Laureano Ramírez-Piscina , José M. Sancho