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Three-dimensional ultrasound localization microscopy (ULM) enables comprehensive visualization of the vasculature, thereby improving diagnostic reliability. Nevertheless, its clinical translation remains challenging, as the exponential…

We present a cost-effective, simple and fast digital holographic microscopy method based upon Rayleigh-Sommerfeld back propagation for identification of the geometrical shape of a cell. The method was tested using synthetic hologram images…

Optics · Physics 2015-10-28 Johan Zakrisson , Staffan Schedin , Magnus Andersson

Investigation of cell structure is hardly imaginable without bright-field microscopy. Numerous modifications such as depth-wise scanning or videoenhancement make this method being state-of-the-art. This raises a question what maximal…

Image and Video Processing · Electrical Eng. & Systems 2020-10-29 Kirill Lonhus , Renata Rychtarikova , Ganna Platonova , Dalibor Stys

Numerous cell types relate to their immediate environment by exerting a three-dimensional pressure field on their environment, with components both longitudinal and transverse to the cell membrane. This pressure field can in principle be…

Soft Condensed Matter · Physics 2026-03-09 Quentin Bédel , Loïc Dupré , Nicolas Destainville

Computational imaging modalities support a simplification of the active architectures required in an imaging system and these approaches have been validated across the electromagnetic spectrum. Recent implementations have utilized…

Classical Physics · Physics 2016-08-24 Thomas Fromenteze , Xiaojun Liu , Michael Boyarsky , Jonah Gollub , David R. Smith

Recent development of lensless imagers has enabled three-dimensional (3D) imaging through a thin piece of optics in close proximity to a camera sensor. A general challenge of wide-field lensless imaging is the high computational complexity…

Optics · Physics 2021-08-17 Feng Tian , Junjie Hu , Weijian Yang

Microcapsules with liquid cores encapsulated by thin membranes have many applications in science, medicine and industry. In this paper, we design a suspension of microcapsules which flow and deform like red blood cells (RBCs), as a valuable…

Soft Condensed Matter · Physics 2023-02-22 Qi Chen , Naval Singh , Kerstin Schirrmann , Qi Zhou , Igor Chernyavsky , Anne Juel

We propose a three-dimensional nonlinear diffusion method to implement the similar autofocusing function of multiple micro-objects and simultaneously remove the defocused images, which can distinguish the locations of certain sized…

Computer Vision and Pattern Recognition · Computer Science 2019-08-15 Wei-Na Li , Zhengyun Zhang , Jianshe Ma , Xiaohao Wang , Ping Su

In this paper, we propose a new model to segment cells in phase contrast microscopy images. Cell images collected from the similar scenario share a similar background. Inspired by this, we separate cells from the background in images by…

Computer Vision and Pattern Recognition · Computer Science 2019-04-02 Lin Zhang

A lens performs an approximately one-to-one mapping from the object to the image planes. This mapping in the image plane is maintained within a depth of field (or referred to as depth of focus, if the object is at infinity). This…

Differential Dynamic Microscopy (DDM) analyzes traditional real-space microscope images to extract information on sample dynamics in a way akin to light scattering, by decomposing each image in a sequence into Fourier modes, and evaluating…

Soft Condensed Matter · Physics 2017-11-10 Fabio Giavazzi , Paolo Edera , Peter J. Lu , Roberto Cerbino

Temporal volume images with 3D+t (4D) information are often used in medical imaging to statistically analyze temporal dynamics or capture disease progression. Although deep-learning-based generative models for natural images have been…

Image and Video Processing · Electrical Eng. & Systems 2022-06-28 Boah Kim , Jong Chul Ye

We present a novel framework to reconstruct complete 3D human shapes from a given target image by leveraging monocular unconstrained images. The objective of this work is to reproduce high-quality details in regions of the reconstructed…

Computer Vision and Pattern Recognition · Computer Science 2024-07-16 Marco Pesavento , Marco Volino , Adrian Hilton

The most ubiquitous form of computational aberration correction for microscopy is deconvolution. However, deconvolution relies on the assumption that the point spread function is the same across the entire field-of-view. This assumption is…

Image and Video Processing · Electrical Eng. & Systems 2025-04-30 Amit Kohli , Anastasios N. Angelopoulos , David McAllister , Esther Whang , Sixian You , Kyrollos Yanny , Federico M. Gasparoli , Bo-Jui Chang , Reto Fiolka , Laura Waller

Fluorescence imaging is indispensable to biology and neuroscience. The need for large-scale imaging in freely behaving animals has further driven the development in miniaturized microscopes (miniscopes). However, conventional microscopes /…

Optics · Physics 2020-10-29 Yujia Xue , Ian G. Davison , David A. Boas , Lei Tian

3D fluorescence microscopy is essential for understanding fundamental life processes through long-term live-cell imaging. However, due to inherent issues in imaging principles, it faces significant challenges including spatially varying…

Image and Video Processing · Electrical Eng. & Systems 2025-03-05 Zelin Li , Chenwei Wang , Zhaoke Huang , Yiming MA , Cunmin Zhao , Zhongying Zhao , Hong Yan

We propose a novel neural deformable model (NDM) targeting at the reconstruction and modeling of 3D bi-ventricular shape of the heart from 2D sparse cardiac magnetic resonance (CMR) imaging data. We model the bi-ventricular shape using…

Computer Vision and Pattern Recognition · Computer Science 2024-11-25 Meng Ye , Dong Yang , Mikael Kanski , Leon Axel , Dimitris Metaxas

We report a new lensless microscopy configuration by integrating the concepts of transverse translational ptychography and defocus multi-height phase retrieval. In this approach, we place a tilted image sensor under the specimen for…

Image and Video Processing · Electrical Eng. & Systems 2021-11-03 Shaowei Jiang , Chengfei Guo , Patrick Hu , Derek Hu , Pengming Song , Tianbo Wang , Zichao Bian , Zibang Zhang , Guoan Zheng

Detail features of magnetic resonance images play a cru-cial role in accurate medical diagnosis and treatment, as they capture subtle changes that pose challenges for doc-tors when performing precise judgments. However, the widely utilized…

Computer Vision and Pattern Recognition · Computer Science 2024-05-10 Mengxiao Geng , Jiahao Zhu , Xiaolin Zhu , Qiqing Liu , Dong Liang , Qiegen Liu

Positron Emission Tomography (PET) is a vital imaging modality widely used in clinical diagnosis and preclinical research but faces limitations in image resolution and signal-to-noise ratio due to inherent physical degradation factors.…

Image and Video Processing · Electrical Eng. & Systems 2024-11-11 Boxiao Yu , Kuang Gong