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Co-clustering simultaneously clusters rows and columns, revealing more fine-grained groups. However, existing co-clustering methods suffer from poor scalability and cannot handle large-scale data. This paper presents a novel and scalable…

Distributed, Parallel, and Cluster Computing · Computer Science 2025-03-20 Zihan Wu , Zhaoke Huang , Hong Yan

The current bulk materials discovery cycle has several inefficiencies from initial computational predictions through fabrication and analyses. Materials are generally evaluated in a singular fashion, relying largely on human-driven…

Materials Science · Physics 2021-02-12 Olivia F. Dippo , Kevin R. Kaufmann , Kenneth S. Vecchio

High-throughput screening (HTS) is a large-scale hierarchical process in which a large number of chemicals are tested in multiple stages. Conventional statistical analyses of HTS studies often suffer from high testing error rates and…

Applications · Statistics 2017-07-13 Tao Feng , Pallavi Basu , Wenguang Sun , Hsun Teresa Ku , Wendy J. Mack

One of the challenges of high granularity calorimeters, such as that to be built to cover the endcap region in the CMS Phase-2 Upgrade for HL-LHC, is that the large number of channels causes a surge in the computing load when clustering…

Instrumentation and Detectors · Physics 2020-01-29 Marco Rovere , Ziheng Chen , Antonio Di Pilato , Felice Pantaleo , Chris Seez

We present a structural clustering algorithm for large-scale datasets of small labeled graphs, utilizing a frequent subgraph sampling strategy. A set of representatives provides an intuitive description of each cluster, supports the…

Databases · Computer Science 2016-10-03 Till Schäfer , Petra Mutzel

Clustering under pairwise constraints is an important knowledge discovery tool that enables the learning of appropriate kernels or distance metrics to improve clustering performance. These pairwise constraints, which come in the form of…

Machine Learning · Computer Science 2022-03-24 Benedikt Boecking , Vincent Jeanselme , Artur Dubrawski

This paper addresses the clustering of data in the hyperdimensional computing (HDC) domain. In prior work, an HDC-based clustering framework, referred to as HDCluster, has been proposed. However, the performance of the existing HDCluster is…

Machine Learning · Computer Science 2024-04-19 Lulu Ge , Keshab K. Parhi

We study the theoretical and practical runtime limits of k-means and k-median clustering on large datasets. Since effectively all clustering methods are slower than the time it takes to read the dataset, the fastest approach is to quickly…

Machine Learning · Computer Science 2024-04-03 Andrew Draganov , David Saulpic , Chris Schwiegelshohn

Identifying cell clusters is a critical step for single-cell transcriptomics study. Despite the numerous clustering tools developed recently, the rapid growth of scRNA-seq volumes prompts for a more (computationally) efficient clustering…

Quantitative Methods · Quantitative Biology 2023-01-11 Nana Wei , Yating Nie , Lin Liu , Xiaoqi Zheng , Hua-Jun Wu4

Innovations in Next-Generation Sequencing are enabling generation of DNA sequence data at ever faster rates and at very low cost. Large sequencing centers typically employ hundreds of such systems. Such high-throughput and low-cost…

Distributed, Parallel, and Cluster Computing · Computer Science 2019-07-31 Vasimuddin Md , Sanchit Misra , Heng Li , Srinivas Aluru

The domain of explainable AI is of interest in all Machine Learning fields, and it is all the more important in clustering, an unsupervised task whose result must be validated by a domain expert. We aim at finding a clustering that has high…

Artificial Intelligence · Computer Science 2024-03-28 Mathieu Guilbert , Christel Vrain , Thi-Bich-Hanh Dao

Clustering is a crucial tool for analyzing data in virtually every scientific and engineering discipline. There are more scalable solutions framed to enable time and space clustering for the future large-scale data analyses. As a result,…

Databases · Computer Science 2023-08-23 D. D. D. Suribabu , T. Hitendra Sarma , B. Eswar Reddy

Clustering algorithms are one of the main analytical methods to detect patterns in unlabeled data. Existing clustering methods typically treat samples in a dataset as points in a metric space and compute distances to group together similar…

Machine Learning · Computer Science 2021-10-12 Tarek Naous , Srinjay Sarkar , Abubakar Abid , James Zou

We present CluStRE, a novel streaming graph clustering algorithm that balances computational efficiency with high-quality clustering using multi-stage refinement. Unlike traditional in-memory clustering approaches, CluStRE processes graphs…

Machine Learning · Computer Science 2025-02-12 Adil Chhabra , Shai Dorian Peretz , Christian Schulz

Metagenomic studies have increasingly utilized sequencing technologies in order to analyze DNA fragments found in environmental samples.One important step in this analysis is the taxonomic classification of the DNA fragments. Conventional…

Genomics · Quantitative Biology 2020-02-11 Andreas Georgiou , Vincent Fortuin , Harun Mustafa , Gunnar Rätsch

In the era of pre-trained models, effective classification can often be achieved using simple linear probing or lightweight readout layers. In contrast, many competitive clustering pipelines have a multi-modal design, leveraging large…

Computer Vision and Pattern Recognition · Computer Science 2025-12-23 Yicen Li , Haitz Sáez de Ocáriz Borde , Anastasis Kratsios , Paul D. McNicholas

Hierarchical clustering (HC) is an important data analysis technique in which the goal is to recursively partition a dataset into a tree-like structure while grouping together similar data points at each level of granularity. Unfortunately,…

Data Structures and Algorithms · Computer Science 2025-06-09 Vladimir Braverman , Jon C. Ergun , Chen Wang , Samson Zhou

Spectral clustering approaches have led to well-accepted algorithms for finding accurate clusters in a given dataset. However, their application to large-scale datasets has been hindered by computational complexity of eigenvalue…

Machine Learning · Computer Science 2016-03-17 Shahzad Bhatti , Carolyn Beck , Angelia Nedic

We propose a novel approach to the problem of clustering hierarchically aggregated time-series data, which has remained an understudied problem though it has several commercial applications. We first group time series at each aggregated…

Machine Learning · Computer Science 2022-05-30 Xing Han , Tongzheng Ren , Jing Hu , Joydeep Ghosh , Nhat Ho

This work aims to improve the sample efficiency of parallel large-scale ranking and selection (R&S) problems by leveraging correlation information. We modify the commonly used "divide and conquer" framework in parallel computing by adding a…

Methodology · Statistics 2026-02-16 Zishi Zhang , Yijie Peng