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The increased adoption of Electronic Health Records(EHRs) has brought changes to the way the patient care is carried out. The rich heterogeneous and temporal data space stored in EHRs can be leveraged by machine learning models to capture…

Machine Learning · Computer Science 2019-04-11 Maria Bampa

Clinical outcome prediction based on the Electronic Health Record (EHR) plays a crucial role in improving the quality of healthcare. Conventional deep sequential models fail to capture the rich temporal patterns encoded in the longand…

Machine Learning · Computer Science 2019-08-27 Luchen Liu , Haoran Li , Zhiting Hu , Haoran Shi , Zichang Wang , Jian Tang , Ming Zhang

Myocardial infarction (MI) is a leading cause of death, and its adverse outcomes are urgent to predict. Yet ECG-based prognostic models underperform because deep learning requires large, labelled datasets, which are scarce in medicine.…

Causal mediation analysis of observational data is an important tool for investigating the potential causal effects of medications on disease-related risk factors, and on time-to-death (or disease progression) through these risk factors.…

Meta-analysis is a powerful tool for assessing drug safety by combining treatment-related toxicological findings across multiple studies, as clinical trials are typically underpowered for detecting adverse drug effects. However, incomplete…

Machine learning models are often trained to predict the outcome resulting from a human decision. For example, if a doctor decides to test a patient for disease, will the patient test positive? A challenge is that historical decision-making…

Machine Learning · Computer Science 2024-04-23 Sidhika Balachandar , Nikhil Garg , Emma Pierson

We present a personalized and reliable prediction model for healthcare, which can provide individually tailored medical services such as diagnosis, disease treatment, and prevention. Our proposed framework targets at making personalized and…

Machine Learning · Statistics 2019-11-26 Ingyo Chung , Saehoon Kim , Juho Lee , Kwang Joon Kim , Sung Ju Hwang , Eunho Yang

The electrocardiogram (ECG) is a widely-used medical test, typically consisting of 12 voltage versus time traces collected from surface recordings over the heart. Here we hypothesize that a deep neural network can predict an important…

Competing risk models are survival models with several events of interest acting in competition and whose occurrence is only observed for the event that occurs first in time. This paper presents a Bayesian approach to these models in which…

Massive sized survival datasets are becoming increasingly prevalent with the development of the healthcare industry. Such datasets pose computational challenges unprecedented in traditional survival analysis use-cases. A popular way for…

Methodology · Statistics 2023-05-09 Nir Keret , Malka Gorfine

We study explained variation under the additive hazards regression model for right-censored data. We consider different approaches for developing such a measure, and focus on one that estimates the proportion of variation in the failure…

Applications · Statistics 2020-09-02 Denise Rava , Ronghui Xu

Recent research has shown the potential for neural networks to improve upon classical survival models such as the Cox model, which is widely used in clinical practice. Neural networks, however, typically rely on data that are centrally…

Machine Learning · Computer Science 2022-07-12 Dekai Zhang , Francesca Toni , Matthew Williams

Intricating cardiac complexities are the primary factor associated with healthcare costs and the highest cause of death rate in the world. However, preventive measures like the early detection of cardiac anomalies can prevent severe…

Machine Learning · Computer Science 2019-04-18 Asim Darwaish , Farid Naït-Abdesselam , Ashfaq Khokhar

In this paper we investigate the estimation of the unknown parameters of a competing risk model based on a Weibull distributed decreasing failure rate and an exponentially distributed constant failure rate, under right censored…

Statistics Theory · Mathematics 2021-01-12 Hamida Talhi , Hiba Aiachi , Nadji Rahmania

Recurrent neural network based solutions are increasingly being used in the analysis of longitudinal Electronic Health Record data. However, most works focus on prediction accuracy and neglect prediction uncertainty. We propose Deep Kernel…

Machine Learning · Computer Science 2021-07-27 Zhiliang Wu , Yinchong Yang , Peter A. Fasching , Volker Tresp

In this paper, we consider survival analysis with right-censored data which is a common situation in predictive maintenance and health field. We propose a model based on the estimation of two-parameter Weibull distribution conditionally to…

Methodology · Statistics 2020-02-24 Achraf Bennis , Sandrine Mouysset , Mathieu Serrurier

Interval censored data commonly arise in medical studies when the event time of interest is only known to lie within an interval. In the presence of a cure subgroup, conventional mixture cure models typically assume a logistic model for the…

Methodology · Statistics 2026-01-21 Xiaoru Huang , Tonghui Yu , Xiaoyu Liu

Cardiovascular disease, especially heart failure is one of the major health hazard issues of our time and is a leading cause of death worldwide. Advancement in data mining techniques using machine learning (ML) models is paving promising…

Machine Learning · Computer Science 2021-08-31 S. M Mehedi Zaman , Wasay Mahmood Qureshi , Md. Mohsin Sarker Raihan , Ocean Monjur , Abdullah Bin Shams

Current status censoring or case I interval censoring takes place when subjects in a study are observed just once to check if a particular event has occurred. If the event is recurring, the data are classified as current count data; if…

Methodology · Statistics 2024-10-15 Pavithra Hariharan , P. G. Sankaran

Accurate prediction of clinical outcomes using Electronic Health Records (EHRs) is critical for early intervention, efficient resource allocation, and improved patient care. EHRs contain multimodal data, including both structured data and…

Machine Learning · Computer Science 2025-08-29 Rituparna Datta , Jiaming Cui , Zihan Guan , Vishal G. Reddy , Joshua C. Eby , Gregory Madden , Rupesh Silwal , Anil Vullikanti
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