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Related papers: Directional locking in deterministic lateral displ…

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We investigate the transport and separation of overdamped particles under the action of a uniform external force in a two-dimensional periodic energy landscape. Exact results are obtained for the deterministic transport in a square lattice…

Soft Condensed Matter · Physics 2013-05-29 John Herrmann , Michael Karweit , German Drazer

We use a macromodel of a flow-driven deterministic lateral displacement (DLD) microfluidic system to investigate conditions leading to size-separation of suspended particles. This model system can be easily reconfigured to establish an…

Fluid Dynamics · Physics 2016-04-27 Siqi Du , German Drazer

This work investigates the migration of spherical particles of different sizes in a centrifuge-driven deterministic lateral displacement (c-DLD) device. Specifically, we use a scaled-up model to study the motion of suspended particles…

Soft Condensed Matter · Physics 2016-04-27 Mingliang Jiang , Aaron D. Mazzeo , German Drazer

We investigate the motion of a suspended non-Brownian sphere past a fixed cylindrical or spherical obstacle in the limit of zero Reynolds number for arbitrary particle-obstacle aspect ratios. We consider both a suspended sphere moving in a…

Fluid Dynamics · Physics 2016-05-04 Sumedh R. Risbud , German Drazer

We investigate the migration of particles of different geometrical shapes and sizes in a scaled-up model of a gravity-driven deterministic lateral displacement (g-DLD) device. Specifically, particles move through a square array of…

Fluid Dynamics · Physics 2016-05-04 Mingliang Jiang , Kostyantyn Budzan , German Drazer

Directional locking occurs when a particle moving over a periodic substrate becomes constrained to travel along certain substrate symmetry directions. Such locking effects arise for colloids and superconducting vortices moving over ordered…

Soft Condensed Matter · Physics 2024-04-23 C. Reichhardt , C. J. O. Reichhardt

An electrokinetically-driven deterministic lateral displacement (e-DLD) device is proposed for the continuous, two-dimensional fractionation of suspensions in microfluidic platforms. The suspended species are driven through an array of…

Fluid Dynamics · Physics 2016-05-04 Srinivas Hanasoge , Raghavendra Devendra , Javier F. Diez , German Drazer

In this paper, we describe the unification and extension of multiple kinematic theories on the advection of colloidal particles through periodic obstacle lattices of arbitrary geometry and infinitesimally small obstacle size. We focus…

Computational Physics · Physics 2020-03-25 Arnaldo Rodriguez-Gonzalez , Jason P. Gleghorn , Brian J. Kirby

Deterministic lateral displacement (DLD) devices separate micrometer-scale particles in solution based on their size using a laminar microfluidic flow in an array of obstacles. We investigate array geometries with rational row-shift…

We present a simple solution to enhance the separation ability of deterministic lateral displacement (DLD) systems by expanding the two-dimensional nature of these devices and driving the particles into size-dependent, fully…

Soft Condensed Matter · Physics 2016-04-27 Siqi Du , German Drazer

We present a computational investigation of the mechanism governing size-based particle separation in microfluidic pinched flow fractionation. We study the behavior of particles moving through a pinching gap (i.e., a constriction in the…

Fluid Dynamics · Physics 2016-05-04 Sumedh R. Risbud , German Drazer

When particles suspended in a fluid are driven through a regular lattice of cylindrical obstacles, the particle motion is usually not simply in the direction of the force, and in the high Peclet number limit particle trajectories tend to…

Soft Condensed Matter · Physics 2016-05-04 J. Koplik , G. Drazer

We study the drift of suspended micro-particles in a viscous liquid pumped back and forth through a periodic lattice of pores (drift ratchet). In order to explain the particle drift observed in such an experiment, we present an…

Fluid Dynamics · Physics 2012-05-22 Philippe Beltrame , Peter Talkner , Peter Hänggi

The ability to separate and analyze chemical species with high resolution, sensitivity, and throughput is central to the development of microfluidics systems. Deterministic lateral displacement (DLD) is a continuous separation method based…

Fluid Dynamics · Physics 2014-04-15 Timothy J. Bowman , German Drazer , Joelle Frechette

Systematic deflection of microparticles off of initial streamlines is a fundamental task in microfluidics, aiming at applications including sorting, accumulation, or capture of the transported particles. In a large class of setups,…

Fluid Dynamics · Physics 2026-04-01 Partha Kumar Das , Xuchen Liu , Sascha Hilgenfeldt

There are many examples of driven and active matter systems containing particles that exhibit circular motion with different chiralities, such as swimming bacteria near surfaces or certain types of self-driven colloidal particles. Circular…

Statistical Mechanics · Physics 2015-06-16 C. Reichhardt , C. J. Olson Reichhardt

Deterministic lateral displacement (DLD) is a high-resolution separation technique used in various fields. A fundamental challenge in DLD is ensuring uniform flow characteristics across channel, particularly near sidewalls where pillar…

Fluid Dynamics · Physics 2025-06-10 Aryan Mehboudi , Shrawan Singhal , S. V. Sreenivasan

Understanding the transport properties of microorganisms and self-propelled particles in porous media has important implications for human health as well as microbial ecology. In free space, most microswimmers perform diffusive random walks…

Soft Condensed Matter · Physics 2023-08-10 David Saintillan

We study the transport properties of a system of active particles moving at constant speed in an heterogeneous two-dimensional space. The spatial heterogeneity is modeled by a random distribution of obstacles, which the active particles…

Biological Physics · Physics 2013-10-23 Oleksandr Chepizhko , Fernando Peruani

Inspired by numerous lab on a chip, biomedical and bioengineering applications such as cell sorting, focusing, trapping, and filtering of particles, manipulation of micron sized particle trajectories has been of significant interest in the…

Fluid Dynamics · Physics 2026-03-18 Partha Kumar Das
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