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Bootstrapping is a popular and computationally demanding resampling method used for measuring the accuracy of sample estimates and assisting with statistical inference. R is a freely available language and environment for statistical…

Computation · Statistics 2014-01-27 T. M. Sloan , M. Piotrowski , T. Forster , P. Ghazal

The sequential parameter optimization (SPOT) package for R is a toolbox for tuning and understanding simulation and optimization algorithms. Model-based investigations are common approaches in simulation and optimization. Sequential…

Neural and Evolutionary Computing · Computer Science 2010-06-25 Thomas Bartz-Beielstein

Two useful strategies to speed up drug development are to increase the patient accrual rate and use novel adaptive designs. Unfortunately, these two strategies often conflict when the evaluation of the outcome cannot keep pace with the…

Methodology · Statistics 2018-07-24 Ruitao Lin , Ying Yuan

Automated test case generation has proven to be useful to reduce the usually high expenses of software testing. However, several studies have also noted the skepticism of testers regarding the comprehension of generated test suites when…

Software Engineering · Computer Science 2024-01-17 Pedro Delgado-Pérez , Aurora Ramírez , Kevin J. Valle-Gómez , Inmaculada Medina-Bulo , José Raúl Romero

Response adaptive randomization (RAR) is appealing from methodological, ethical, and pragmatic perspectives in the sense that subjects are more likely to be randomized to better performing treatment groups based on accumulating data.…

Methodology · Statistics 2022-08-03 Tianyu Zhan , Lu Cui , Ziqian Geng , Lanju Zhang , Yihua Gu , Ivan S. F. Chan

Participation incentives is a well-known issue inhibiting randomized controlled trials (RCTs) in medicine, as well as a potential cause of user dissatisfaction for RCTs in online platforms. We frame this issue as a non-standard…

Computer Science and Game Theory · Computer Science 2026-01-13 Yingkai Li , Aleksandrs Slivkins

Linear discriminant analysis (LDA) is a powerful tool in building classifiers with easy computation and interpretation. Recent advancements in science technology have led to the popularity of datasets with high dimensions, high orders and…

Computation · Statistics 2019-04-09 Yuqing Pan , Qing Mai , Xin Zhang

Item response theory (IRT) models are a class of statistical models used to describe the response behaviors of individuals to a set of items having a certain number of options. They are adopted by researchers in social science, particularly…

Computation · Statistics 2014-04-16 Angelo Mazza , Antonio Punzo , Brian McGuire

We introduce OrigamiPlot, an open-source R package and Shiny web application designed to enhance the visualization of multivariate data. This package implements the origami plot, a novel visualization technique proposed by Duan et al. in…

Human-Computer Interaction · Computer Science 2024-11-20 Yiwen Lu , Jiayi Tong , Yuqing Lei , Alex J. Sutton , Haitao Chu , Lisa D. Levine , Thomas Lumley , David A. Asch , Rui Duan , Christopher H. Schmid , Yong Chen

In randomized clinical trials, adjustments for baseline covariates at both design and analysis stages are highly encouraged by regulatory agencies. A recent trend is to use a model-assisted approach for covariate adjustment to gain…

Methodology · Statistics 2021-07-14 Ting Ye , Jun Shao , Yanyao Yi , Qingyuan Zhao

Randomized experiments have been the gold standard for assessing the effectiveness of a treatment or policy. The classical complete randomization approach assigns treatments based on a prespecified probability and may lead to inefficient…

Methodology · Statistics 2023-10-26 Waverly Wei , Xinwei Ma , Jingshen Wang

To increase statistical efficiency in a randomized experiment, researchers often use stratification (i.e., blocking) in the design stage. However, conventional practices of stratification fail to exploit valuable information about the…

Methodology · Statistics 2025-10-28 Zikai Li

Since software performance requirements are documented in natural language, quantifying them into mathematical forms is essential for software engineering. Yet, the vagueness in performance requirements and uncertainty of human cognition…

Software Engineering · Computer Science 2026-04-28 Shihai Wang , Tao Chen

Cross-fitting is a key ingredient in many semiparametric estimation procedures, such as double/debiased machine learning (DML), enabling valid estimation of low-dimensional targets in the presence of high-dimensional nuisance functions by…

Computation · Statistics 2026-05-18 Etienne Peyrot , François Petit

The goal of the linear law-based feature space transformation (LLT) algorithm is to assist with the classification of univariate and multivariate time series. The presented R package, called LLT, implements this algorithm in a flexible yet…

Machine Learning · Computer Science 2026-02-06 Marcell T. Kurbucz , Péter Pósfay , Antal Jakovác

We propose a novel adaptive design for clinical trials with time-to-event outcomes and covariates (which may consist of or include biomarkers). Our method is based on the expected entropy of the posterior distribution of a proportional…

Applications · Statistics 2016-03-29 James E. Barrett

Clinical trial adaptation refers to any adjustment of the trial protocol after the onset of the trial. The main goal is to make the process of introducing new medical interventions to patients more efficient by reducing the cost and the…

Machine Learning · Computer Science 2014-11-17 Ognjen Arandjelovic

Accurately assessing internal human states is key to understanding preferences, offering personalized services, and identifying challenges in real-world applications. Originating from psychometrics, adaptive testing has become the…

Artificial Intelligence · Computer Science 2025-06-04 Junhao Yu , Yan Zhuang , YuXuan Sun , Weibo Gao , Qi Liu , Mingyue Cheng , Zhenya Huang , Enhong Chen

In order to get accurate information about complex systems depending on a lot of parameters, frequently different experimental methods and/or different experimental conditions are used. The evaluation of these data sets is quite often a…

Other Condensed Matter · Physics 2009-07-17 Sz. Sajti , L. Deák , L. Bottyán

Randomized control trials (RCTs) have been the gold standard to evaluate the effectiveness of a program, policy, or treatment on an outcome of interest. However, many RCTs assume that study participants are willing to share their…

Applications · Statistics 2021-12-07 Manjusha Kancharla , Hyunseung Kang
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