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Hebbian theory seeks to explain how the neurons in the brain adapt to stimuli, to enable learning. An interesting feature of Hebbian learning is that it is an unsupervised method and as such, does not require feedback, making it suitable in…

Neurons and Cognition · Quantitative Biology 2022-06-07 Jakub Fil , Neil Dalchau , Dominique Chu

Learning is a physical process. Here, we aim to study a simple dynamical system composed of springs and sticks capable of arbitrarily approximating any continuous function. The main idea of our work is to use the sticks to mimic a…

Machine Learning · Computer Science 2025-08-27 Luis Mantilla Calderón , Alán Aspuru-Guzik

We study the on-line AdaTron learning of linearly non-separable rules by a simple perceptron. Training examples are provided by a perceptron with a non-monotonic transfer function which reduces to the usual monotonic relation in a certain…

Condensed Matter · Physics 2009-10-30 Jun-ichi Inoue , Hidetoshi Nishimori

For the past two decades, researchers have attempted to create a Quantum Neural Network (QNN) by combining the merits of quantum computing and neural computing. In order to exploit the advantages of the two prolific fields, the QNN must…

Quantum Physics · Physics 2015-12-15 Kok-Leong Seow , Elizabeth Behrman , James Steck

We develop a framework for optimizing a novel approach to extending the linear range of bioanalytical systems and biosensors by utilizing two enzymes with different kinetic responses to the input chemical as their substrate. Data for the…

Molecular Networks · Quantitative Biology 2013-05-28 Vladimir Privman , Oleksandr Zavalov , Aleksandr Simonian

Digital signal processing is the cornerstone of several modern-day technologies, yet in multiple applications it faces critical bottlenecks related to memory and speed constraints. Thanks to recent advances in metasurface design and…

Living microorganisms have evolved dedicated sensory machinery to detect environmental perturbations, processing these signals through biochemical networks to guide behavior. Replicating such capabilities in synthetic active matter remains…

Soft Condensed Matter · Physics 2025-12-25 Diptabrata Paul , Nikola Milosevic , Nico Scherf , Frank Cichos

While the identification of nonlinear dynamical systems is a fundamental building block of model-based reinforcement learning and feedback control, its sample complexity is only understood for systems that either have discrete states and…

Machine Learning · Statistics 2020-06-19 Horia Mania , Michael I. Jordan , Benjamin Recht

Simple memorizing tasks have been chosen such as a binary code on a matrix. After the establishment of an appropriate protocol, the codified matrices were individually presented to 150 university students who had to memorize them. A…

Neurons and Cognition · Quantitative Biology 2007-05-23 Alexandra C. Tsallis , Constantino Tsallis , Aglae C. N. de Magalhaes , Francisco A. Tamarit

We investigate the generalization ability of a perceptron with non-monotonic transfer function of a reversed-wedge type in on-line mode. This network is identical to a parity machine, a multilayer network. We consider several learning…

Disordered Systems and Neural Networks · Physics 2009-10-30 Jun-ichi Inoue , Hidetoshi Nishimori , Yoshiyuki Kabashima

In the control of classical mechanical systems, the feedback has been successfully applied to the production of the desired nonlinear dynamics. However, how much this can be done is still an open problem in quantum mechanical systems. This…

Quantum Physics · Physics 2012-07-24 Jing Zhang , Re-Bing Wu , Yu-xi Liu , Chun-Wen Li , Tzyh-Jong Tarn

Deep learning models have become fundamental tools in drug design. In particular, large language models trained on biochemical sequences learn feature vectors that guide drug discovery through virtual screening. However, such models do not…

Biomolecules · Quantitative Biology 2025-03-28 Joseph D. Clark , Tanner J. Dean , Diwakar Shukla

In the present paper a newer application of Artificial Neural Network (ANN) has been developed i.e., predicting response-function results of electrical-mechanical system through ANN. This method is specially useful to complex systems for…

Neural and Evolutionary Computing · Computer Science 2011-11-09 R. C. Gupta , Ankur Agarwal , Ruchi Gupta , Sanjay Gupta

Bioprocess mechanistic modeling is essential for advancing intelligent digital twin representation of biomanufacturing, yet challenges persist due to complex intracellular regulation, stochastic system behavior, and limited experimental…

Machine Learning · Statistics 2025-05-07 Keilung Choy , Wei Xie , Keqi Wang

Neural networks are exerting burgeoning influence in emerging artificial intelligence applications at the micro-edge, such as sensing systems and image processing. As many of these systems are typically self-powered, their circuits are…

Signal Processing · Electrical Eng. & Systems 2019-10-21 Sergey Mileiko , Rishad Shafik , Alex Yakovlev , Jonathan Edwards

The ever-growing demand for further advances in artificial intelligence motivated research on unconventional computation based on analog physical devices. While such computation devices mimic brain-inspired analog information processing,…

Neural and Evolutionary Computing · Computer Science 2022-05-02 Mitsumasa Nakajima , Katsuma Inoue , Kenji Tanaka , Yasuo Kuniyoshi , Toshikazu Hashimoto , Kohei Nakajima

Biomimicry is a powerful science that takes advantage of nature's remarkable ability to devise innovative solutions to challenging problems. In this work, we use asymptotic methods to develop the mathematical foundations for the exchange of…

Analysis of PDEs · Mathematics 2022-09-26 Habib Ammari , Bryn Davies

Learning latent representations has aided operational decision-making in several disciplines. Its advantages include uncovering hidden interactions in data and automating procedures which were performed manually in the past. Representation…

Machine Learning · Computer Science 2022-05-19 Christos Pylianidis , Ioannis N. Athanasiadis

Retrosynthesis analysis is a critical task in organic chemistry central to many important industries. Previously, various machine learning approaches have achieved promising results on this task by representing output molecules as strings…

Quantitative Methods · Quantitative Biology 2022-09-20 Lei Fang , Junren Li , Ming Zhao , Li Tan , Jian-Guang Lou

We present a benchmark study of autonomous, chemical agents exhibiting associative learning of an environmental feature. Associative learning has been widely studied in cognitive science and artificial intelligence, but are most commonly…

Adaptation and Self-Organizing Systems · Physics 2022-10-12 Stuart Bartlett , David Louapre