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Cilia are elastic hairlike protuberances of the cell membrane found in various unicellular organisms and in several tissues of most living organisms. In some tissues such as the airway tissues of the lung, the coordinated beating of cilia…

Soft Condensed Matter · Physics 2018-01-15 Supravat Dey , Gladys Massiera , Estelle Pitard

To gain insight into the nature of biological synchronization at the microscopic scale, we here investigate the hydrodynamic synchronization between conically rotating objects termed nodal cilia. A mechanical model of three rotating cilia…

Soft Condensed Matter · Physics 2018-03-28 Keiji Okumura , Seiya Nishikawa , Toshihiro Omori , Takuji Ishikawa , Atsuko Takamatsu

In this work we study the effect of metachronal waves on the flow created by magnetically-driven plate-like artificial cilia in microchannels using numerical simulations. The simulations are performed using a coupled magneto-mechanical…

Fluid Dynamics · Physics 2015-05-30 Syed Khaderi , Jaap den Toonder , Patrick Onck

Biological systems are robust to perturbations at both the genetic and environmental levels. Yet, these same perturbations can elicit variation in behavior. The interplay between functional robustness and behavioral variability is…

Biological Physics · Physics 2021-06-03 Veikko Geyer , Jonathon Howard , Pablo Sartori

Tiny cilia drive the flow of surrounding fluids through asymmetric jumping, which is one of the main ways for biological organisms to control fluid transport at the micro-scale. Due to its huge application prospects in medical and…

Optimization and Control · Mathematics 2024-01-08 Shuangshuang Yu , Zheng Ning , Ge Chen

The present work reports the formation and the characterization of antipleptic and symplectic metachronal waves in 3D cilia arrays immersed in a two-fluid environment, with a viscosity ratio of 20. A coupled…

Biological Physics · Physics 2017-08-02 Sylvain Chateau , Julien Favier , Umberto D 'Ortona , Sébastien Poncet

Fish typically swim by periodic bending of their bodies. Bending seems to follow a universal rule; it occurs at about one-third from the posterior end of the fish body with a maximum bending angle of about $30^o$. However, the hydrodynamic…

Fluid Dynamics · Physics 2021-12-22 Haotian Hang , Sina Heydari , John H. Costello , Eva Kanso

Synchronization among arrays of beating cilia is one of the emergent phenomena in biological processes at meso-scopic scales. Strong inter-ciliary couplings modify the natural beating frequencies, $\omega$, of individual cilia to produce a…

Statistical Mechanics · Physics 2021-06-09 Hyunsuk Hong , Junghyo Jo , Changbong Hyeon , Hyunggyu Park

One of the vital functions of naturally occurring cilia is fluid transport. Biological cilia use spatially asymmetric strokes to generate a net fluid flow that can be utilized for feeding, swimming, and other functions. Biomimetic synthetic…

Fluid Dynamics · Physics 2018-07-19 Srinivas Hanasoge , Peter J. Hesketh , Alexander Alexeev

By taking into account the hydrodynamic interactions in a one dimensional array of model cilia attached to a no-slip cylinderical surface, we investigate their synchronized motion. We show, how does the emergence of metachronal waves depend…

Biological Physics · Physics 2017-05-31 Aref Ghorbani , Ali Najafi

Synchronization induced by long-range hydrodynamic interactions is attracting attention as a candidate mechanism behind coordinated beating of cilia and flagella. Here we consider a minimal model of hydrodynamic synchronization in the low…

Soft Condensed Matter · Physics 2012-11-26 Nariya Uchida , Ramin Golestanian

Direct mechanical coupling is known to be critical for establishing synchronization among cilia. However, the actual role of the connections is still elusive - partly because controlled experiments in live samples are challenging. Here, we…

Soft Condensed Matter · Physics 2023-12-27 Yiming Xia , Zixian Hu , Da Wei , Ke Chen , Yi Peng , Mingcheng Yang

Cellular appendages conferring motility, such as flagella or cilia, are known to synchronise their periodic beats. The origin of synchronisation is a combination of long-range hydrodynamic interactions with physical mechanisms allowing the…

Biological Physics · Physics 2021-04-21 Ivan Tanasijević , Eric Lauga

Synchronisation is often observed in the swimming of flagellated cells, either for multiple appendages on the same organism or between the flagella of nearby cells. Beating cilia are also seen to synchronise their dynamics. In 1951, Taylor…

Biological Physics · Physics 2021-04-28 Weida Liao , Eric Lauga

The time dynamics of flagellar and ciliary beating is often neglected in theories of microswimmers, with the most common models prescribing a time-constant actuation of the surrounding fluid. By explicitly introducing a metachronal wave,…

Soft Condensed Matter · Physics 2026-01-19 G. C. Antunes , H. Stark

A remarkable variety of organisms use metachronal coordination (i.e., numerous neighboring appendages beating sequentially with a fixed phase lag) to swim or pump fluid. This coordination strategy is used by microorganisms to break symmetry…

Biological Physics · Physics 2024-07-22 David J. Peterman , Margaret L. Byron

Synchronization of actively oscillating organelles such as cilia and flagella facilitates self-propulsion of cells and pumping fluid in low Reynolds number environments. To understand the key mechanism behind synchronization induced by…

Soft Condensed Matter · Physics 2015-05-20 Nariya Uchida , Ramin Golestanian

Cilia and flagella are actively bending slender organelles, performing functions such as motility, feeding and embryonic symmetry breaking. We review the mechanics of viscous-dominated microscale flow, including time-reversal symmetry, drag…

Quantitative Methods · Quantitative Biology 2013-09-06 Thomas D. Montenegro-Johnson , Andrew A. Smith , David J. Smith , Daniel Loghin , John R. Blake

By numerical modeling we investigate fluid transport in low-Reynolds-number flow achieved with a special elastic filament or artifical cilium attached to a planar surface. The filament is made of superparamagnetic particles linked together…

Soft Condensed Matter · Physics 2008-11-25 Erik M. Gauger , Matthew Downton , Holger Stark

Interactions between swimming cells and surfaces are essential to many microbiological processes, from bacterial biofilm formation to human fertilization. However, in spite of their fundamental importance, relatively little is known about…

Biological Physics · Physics 2013-02-04 Vasily Kantsler , Jörn Dunkel , Marco Polin , Raymond E. Goldstein