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3D imaging modalities are becoming increasingly popular and relevant in retinal imaging owing to their effectiveness in highlighting structures in sub-retinal layers. OCT is one such modality which has great importance in the context of…

Computer Vision and Pattern Recognition · Computer Science 2016-12-09 Karthik Gopinath , Jayanthi Sivaswamy

Optical Coherence Tomography (OCT) is one of the most emerging imaging modalities that has been used widely in the field of biomedical imaging. From its emergence in 1990's, plenty of hardware and software improvements have been made. Its…

Computer Vision and Pattern Recognition · Computer Science 2014-11-18 Ahmadreza Baghaie , Roshan M. D'souza , Zeyun Yu

Optical coherence tomography (OCT) is a non-invasive, micrometer-scale imaging modality that has become a clinical standard in ophthalmology. By raster-scanning the retina, sequential cross-sectional image slices are acquired to generate…

Image and Video Processing · Electrical Eng. & Systems 2024-02-20 Stefan Ploner , Jungeun Won , Julia Schottenhamml , Jessica Girgis , Kenneth Lam , Nadia Waheed , James Fujimoto , Andreas Maier

We present a pseudo-real-time retinal layer segmentation for high-resolution Sensorless Adaptive Optics-Optical Coherence Tomography (SAO-OCT). Our pseudo-real-time segmentation method is based on Dijkstra's algorithm that uses the…

Image and Video Processing · Electrical Eng. & Systems 2020-04-14 Worawee Janpongsri , Joey Huang , Ringo Ng , Daniel J. Wahl , Marinko V. Sarunic , Yifan Jian

Optical coherence tomography (OCT) is a noninvasive imaging modality which can be used to obtain depth images of the retina. The changing layer thicknesses can thus be quantified by analyzing these OCT images, moreover these changes have…

Computer Vision and Pattern Recognition · Computer Science 2018-03-15 Yufan He , Aaron Carass , Bruno M. Jedynak , Sharon D. Solomon , Shiv Saidha , Peter A. Calabresi , Jerry L. Prince

The treatment of age-related macular degeneration (AMD) requires continuous eye exams using optical coherence tomography (OCT). The need for treatment is determined by the presence or change of disease-specific OCT-based biomarkers.…

Image and Video Processing · Electrical Eng. & Systems 2026-03-12 Timo Kepp , Helge Sudkamp , Claus von der Burchard , Hendrik Schenke , Peter Koch , Gereon Hüttmann , Johann Roider , Mattias P. Heinrich , Heinz Handels

Purpose. Localizing structures and estimating the motion of a specific target region are common problems for navigation during surgical interventions. Optical coherence tomography (OCT) is an imaging modality with a high spatial and…

Image and Video Processing · Electrical Eng. & Systems 2020-04-22 Marcel Bengs , Nils Gessert , Matthias Schlüter , Alexander Schlaefer

Focusing on the complicated pathological features, such as blurred boundaries, severe scale differences between symptoms, background noise interference, etc., in the task of retinal edema lesions joint segmentation from OCT images and…

Image and Video Processing · Electrical Eng. & Systems 2024-01-03 Meng Wang , Kai Yu , Chun-Mei Feng , Ke Zou , Yanyu Xu , Qingquan Meng , Rick Siow Mong Goh , Yong Liu , Huazhu Fu

In this paper, we design a Generative Adversarial Network (GAN)-based solution for super-resolution and segmentation of optical coherence tomography (OCT) scans of the retinal layers. OCT has been identified as a non-invasive and…

Image and Video Processing · Electrical Eng. & Systems 2022-06-29 Paria Jeihouni , Omid Dehzangi , Annahita Amireskandari , Ali Rezai , Nasser M. Nasrabadi

The optic nerve head represents the intraocular section of the optic nerve (ONH), which is prone to damage by intraocular pressure. The advent of optical coherence tomography (OCT) has enabled the evaluation of novel optic nerve head…

Optical coherence tomography (OCT) is widely used for diagnosing and monitoring retinal diseases, such as age-related macular degeneration (AMD). The segmentation of biomarkers such as layers and lesions is essential for patient diagnosis…

Computer Vision and Pattern Recognition · Computer Science 2025-09-26 Botond Fazekas , Guilherme Aresta , Philipp Seeböck , Julia Mai , Ursula Schmidt-Erfurth , Hrvoje Bogunović

Automated and accurate segmentation of cystoid structures in Optical Coherence Tomography (OCT) is of interest in the early detection of retinal diseases. It is, however, a challenging task. We propose a novel method for localizing cysts in…

Computer Vision and Pattern Recognition · Computer Science 2017-08-29 Karthik Gopinath , Jayanthi Sivaswamy

Background: Changes in choroidal thickness are associated with various ocular diseases and the choroid can be imaged using spectral-domain optical coherence tomography (SDOCT) and enhanced depth imaging OCT (EDIOCT). New Method: Eighty…

An accurate and automated tissue segmentation algorithm for retinal optical coherence tomography (OCT) images is crucial for the diagnosis of glaucoma. However, due to the presence of the optic disc, the anatomical structure of the…

Image and Video Processing · Electrical Eng. & Systems 2021-02-10 Jiaxuan Li , Peiyao Jin , Jianfeng Zhu , Haidong Zou , Xun Xu , Min Tang , Minwen Zhou , Yu Gan , Jiangnan He , Yuye Ling , Yikai Su

This paper presents a novel automated system that segments six sub-retinal layers from optical coherence tomography (OCT) image stacks of healthy patients and patients with diabetic macular edema (DME). First, each image in the OCT stack is…

Computer Vision and Pattern Recognition · Computer Science 2016-10-25 Sohini Roychowdhury , Dara D. Koozekanani , Michael Reinsbach , Keshab K. Parhi

This paper presents an innovative approach to intraoperative Optical Coherence Tomography (iOCT) image segmentation in ophthalmic surgery, leveraging statistical analysis of speckle patterns to incorporate statistical pathology-specific…

Image and Video Processing · Electrical Eng. & Systems 2024-10-27 Kristina Mach , Hessam Roodaki , Michael Sommersperger , Nassir Navab

Dispersion is a common phenomenon in optics due to the frequency dependence of the refractive index in polychromatic light. This issue, if left untreated in optical coherence tomography (OCT) imaging, leads to signal broadening of the…

Image and Video Processing · Electrical Eng. & Systems 2022-01-03 Shangbang Luo , Guy Holland , Eric Mikula , Samantha Bradford , Reza Khazaeinezhad , James V Jester , Tibor Juhasz

Optical coherence tomography (OCT) is a non-invasive volumetric imaging modality with high spatial and temporal resolution. For imaging larger tissue structures, OCT probes need to be moved to scan the respective area. For handheld…

Computer Vision and Pattern Recognition · Computer Science 2026-03-24 Suresh Guttikonda , Maximilian Neidhardt , Vidas Raudonis , Alexander Schlaefer

Optical coherence tomography (OCT) is a prevalent non-invasive imaging method which provides high resolution volumetric visualization of retina. However, its inherent defect, the speckle noise, can seriously deteriorate the tissue…

Computer Vision and Pattern Recognition · Computer Science 2022-01-31 Dewei Hu , Yuankai K. Tao , Ipek Oguz

In this paper, we propose a novel retinal layer boundary model for segmentation of optical coherence tomography (OCT) images. The retinal layer boundary model consists of 9 open parametric contours representing the 9 retinal layers in OCT…

Computer Vision and Pattern Recognition · Computer Science 2018-08-10 Jinming Duan , Weicheng Xie , Ryan Wen Liu , Christopher Tench , Irene Gottlob , Frank Proudlock , Li Bai