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Missing data is a challenge when developing, validating and deploying clinical prediction models (CPMs). Traditionally, decisions concerning missing data handling during CPM development and validation havent accounted for whether…

Retrieval-Augmented Generation (RAG) systems are deployed across federal agencies for citizen-facing tax guidance, benefits eligibility, and legal information, where a single incorrect number causes direct financial harm. This paper proves…

Cryptography and Security · Computer Science 2026-04-07 KrishnaSaiReddy Patil

The customer baseline is required to assign rebates to participants in baseline-based demand response (DR) programs. The average baseline method has been widely accepted in practice due to its simplicity and reliability. However, the…

Systems and Control · Electrical Eng. & Systems 2020-11-24 Xiaochu Wang , Wenyuan Tang

Electronic health records (EHR's) are only a first step in capturing and utilizing health-related data - the problem is turning that data into useful information. Models produced via data mining and predictive analysis profile inherited…

Databases · Computer Science 2011-12-08 Casey Bennett , Thomas Doub

We propose a Bayesian nonparametric (BNP) approach to causal inference using observational data consisting of outcome, treatment, and a set of confounders. The conditional distribution of the outcome given treatment and confounders is…

Methodology · Statistics 2025-12-01 Yongseok Hur , Joonhyuk Jung , Juhee Lee

There has been a misconception that only one type of error rate control is necessary in clinical trials, leading to debates over whether to prioritize Familywise Error Rate (FWER) or False Discovery Rate (FDR). This misconception has led to…

Methodology · Statistics 2026-03-26 Xinping Cui , Emily Ouyang , Yi Liu , Jingjing Yan Schneider , Hong Tian , Bushi Wang , Jason C. Hsu

Artificial intelligence (AI) systems are increasingly integrated into healthcare and pharmacy workflows, supporting tasks such as medication recommendations, dosage determination, and drug interaction detection. While these systems often…

Artificial Intelligence · Computer Science 2026-05-21 Khalid Adnan Alsayed

A common concern when a policymaker draws causal inferences from and makes decisions based on observational data is that the measured covariates are insufficiently rich to account for all sources of confounding, i.e., the standard no…

Methodology · Statistics 2023-10-25 Tao Shen , Yifan Cui

An estimated 180 papers focusing on deep learning and EHR were published between 2010 and 2018. Despite the common workflow structure appearing in these publications, no trusted and verified software framework exists, forcing researchers to…

Finding suitable health insurance coverage can be challenging for individuals and small enterprises in the USA. The Health Insurance Exchange Public Use Files (Exchange PUFs) dataset provided by CMS offers valuable information on health and…

Machine Learning · Computer Science 2023-10-16 Aishwarya Gupta , Rahul S. Bhogale , Priyanka Thota , Prathushkumar Dathuri , Jongwook Woo

According to the American Diabetes Association(ADA), 30.3 million people in the United States have diabetes, but only 7.2 million may be undiagnosed and unaware of their condition. Type 2 diabetes is usually diagnosed for most patients…

Machine Learning · Computer Science 2019-10-22 Ramya Akula , Ni Nguyen , Ivan Garibay

Missing data is a common concern in health datasets, and its impact on good decision-making processes is well documented. Our study's contribution is a methodology for tackling missing data problems using a combination of synthetic dataset…

Machine Learning · Computer Science 2022-11-08 Gift Khangamwa , Terence L. van Zyl , Clint J. van Alten

Medication recommendation systems have gained significant attention in healthcare as a means of providing tailored and effective drug combinations based on patients' clinical information. However, existing approaches often suffer from…

Machine Learning · Computer Science 2024-08-13 Zihao Zhao , Yi Jing , Fuli Feng , Jiancan Wu , Chongming Gao , Xiangnan He

Current medical language model (LM) benchmarks often over-simplify the complexities of day-to-day clinical practice tasks and instead rely on evaluating LMs on multiple-choice board exam questions. In psychiatry especially, these challenges…

We consider the problem of designing a survey to aggregate non-verifiable information from a privacy-sensitive population: an analyst wants to compute some aggregate statistic from the private bits held by each member of a population, but…

Computer Science and Game Theory · Computer Science 2014-04-25 Arpita Ghosh , Katrina Ligett , Aaron Roth , Grant Schoenebeck

Each year, almost 10% of claims are denied by payers (i.e., health insurance plans). With the cost to recover these denials and underpayments, predicting payer response (likelihood of payment) from claims data with a high degree of accuracy…

Machine Learning · Computer Science 2020-07-14 Byung-Hak Kim , Seshadri Sridharan , Andy Atwal , Varun Ganapathi

Highly regulated industries, like banking and insurance, ask for transparent decision-making algorithms. At the same time, competitive markets are pushing for the use of complex black box models. We therefore present a procedure to develop…

Machine Learning · Statistics 2020-12-11 Roel Henckaerts , Katrien Antonio , Marie-Pier Côté

Inpatient care is a large share of total health care spending, making analysis of inpatient utilization patterns an important part of understanding what drives health care spending growth. Common features of inpatient utilization measures…

Machine Learning · Statistics 2017-11-22 Christoph Kurz , Laura Hatfield

We consider the problem of implementing an individually rational, asymptotically Pareto optimal allocation in a barter-exchange economy where agents are endowed with goods and have preferences over the goods of others, but may not use money…

Computer Science and Game Theory · Computer Science 2015-02-16 Sampath Kannan , Jamie Morgenstern , Ryan Rogers , Aaron Roth

The technical landscape of clinical machine learning is shifting in ways that destabilize pervasive assumptions about the nature and causes of algorithmic bias. On one hand, the dominant paradigm in clinical machine learning is narrow in…

Computers and Society · Computer Science 2023-05-09 Geoff Keeling