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Regression-based predictive analytics used in modern kidney transplantation is known to inherit biases from training data. This leads to social discrimination and inefficient organ utilization, particularly in the context of a few social…

Human-Computer Interaction · Computer Science 2025-05-13 Mukund Telukunta , Venkata Sriram Siddhardh Nadendla , Morgan Stuart , Casey Canfield

Large language models (LLMs) have demonstrated significant potential in clinical decision support. Yet LLMs still suffer from hallucinations and lack fine-grained contextual medical knowledge, limiting their high-stake healthcare…

Computation and Language · Computer Science 2025-04-22 Pengcheng Jiang , Cao Xiao , Minhao Jiang , Parminder Bhatia , Taha Kass-Hout , Jimeng Sun , Jiawei Han

Accurate models of clinical actions and their impacts on disease progression are critical for estimating personalized optimal dynamic treatment regimes (DTRs) in medical/health research, especially in managing chronic conditions.…

Methodology · Statistics 2021-02-19 William Hua , Hongyuan Mei , Sarah Zohar , Magali Giral , Yanxun Xu

The estimation of conditional average treatment effects (CATEs) is an important topic in many scientific fields. CATEs can be estimated with high accuracy if data distributed across multiple parties are centralized. However, it is difficult…

Methodology · Statistics 2025-07-28 Yuji Kawamata , Ryoki Motai , Yukihiko Okada , Akira Imakura , Tetsuya Sakurai

We outline a Bayesian model-averaged meta-analysis for standardized mean differences in order to quantify evidence for both treatment effectiveness $\delta$ and across-study heterogeneity $\tau$. We construct four competing models by…

Stochastic state-transition models of infectious disease transmission can be used to deduce relevant drivers of transmission when fitted to data using statistically principled methods. Fitting this individual-level data requires inference…

Methodology · Statistics 2026-02-12 James Neill , Lloyd A. C. Chapman , Chris Jewell

Accurate prediction of outcomes is crucial for clinical decision-making and personalized patient care. Supervised machine learning algorithms, which are commonly used for outcome prediction in the medical domain, optimize for predictive…

Machine Learning · Computer Science 2026-02-09 Nithya Bhasker , Fiona R. Kolbinger , Susu Hu , Gitta Kutyniok , Stefanie Speidel

Bayesian models are increasing fit to large administrative data sets and then used to make individualized recommendations. For instance, Medicare's Hospital Compare webpage provides information to patients about specific hospital mortality…

Applications · Statistics 2018-04-03 E. I. George , V. Rockova , P. R. Rosenbaum , V. A. Satopaa , J. H. Silber

It is not clear how to target patients who are most likely to benefit from digital care management programs ex-ante, a shortcoming of current risk score based approaches. This study focuses on defining impactability by identifying those…

Quantitative Methods · Quantitative Biology 2019-05-16 Heather Mattie , Patrick Reidy , Patrik Bachtiger , Emily Lindemer , Mohammad Jouni , Trishan Panch

We describe the Bedside Patient Rescue (BPR) project, the goal of which is risk prediction of adverse events for non-ICU patients using ~200 variables (vitals, lab results, assessments, ...). There are several missing predictor values for…

Symptom checkers have emerged as an important tool for collecting symptoms and diagnosing patients, minimizing the involvement of clinical personnel. We developed a machine-learning-backed system, SmartTriage, which goes beyond conventional…

Computation and Language · Computer Science 2021-11-15 Ilya Valmianski , Nave Frost , Navdeep Sood , Yang Wang , Baodong Liu , James J. Zhu , Sunil Karumuri , Ian M. Finn , Daniel S. Zisook

The use of multiple drugs accounts for almost 30% of all hospital admission and is the 5th leading cause of death in America. Since over 30% of all adverse drug events (ADEs) are thought to be caused by drug-drug interactions (DDI), better…

Quantitative Methods · Quantitative Biology 2020-09-02 Ricky Wang

The United States Food and Drug Administration's (FDA's) 510(k) pathway allows manufacturers to gain medical device approval by demonstrating substantial equivalence to a legally marketed device. However, the inherent ambiguity of this…

Machine Learning · Computer Science 2026-01-30 Mohammad Zhalechian , Soroush Saghafian , Omar Robles

The increased availability of medical data has significantly impacted healthcare by enabling the application of machine / deep learning approaches in various instances. However, medical datasets are usually small and scattered across…

Extracting relevant information from medical conversations and providing it to doctors and patients might help in addressing doctor burnout and patient forgetfulness. In this paper, we focus on extracting the Medication Regimen (dosage and…

Computation and Language · Computer Science 2020-10-13 Sai P. Selvaraj , Sandeep Konam

We develop and evaluate a data-driven approach for detecting unusual (anomalous) patient-management decisions using past patient cases stored in electronic health records (EHRs). Our hypothesis is that a patient-management decision that is…

Machine Learning · Computer Science 2026-05-12 Miloš Hauskrecht , Iyad Batal , Michal Valko , Shyam Visweswaran , Gregory F. Cooper , Gilles Clermont

The burden of diseases is rising worldwide, with unequal treatment efficacy for patient populations that are underrepresented in clinical trials. Healthcare, however, is driven by the average population effect of medical treatments and,…

Machine Learning · Computer Science 2024-02-08 Ghadeer O. Ghosheh , Moritz Gögl , Tingting Zhu

Machine learning systems trained on electronic health records (EHRs) increasingly guide treatment decisions, but their reliability depends on the critical assumption that patients follow the prescribed treatments recorded in EHRs. Using EHR…

Machine Learning · Computer Science 2025-04-22 Zhongyuan Liang , Arvind Suresh , Irene Y. Chen

Trauma mortality results from a multitude of non-linear dependent risk factors including patient demographics, injury characteristics, medical care provided, and characteristics of medical facilities; yet traditional approach attempted to…

Machine Learning · Computer Science 2020-09-11 Joshua D. Cardosi , Herman Shen , Jonathan I. Groner , Megan Armstrong , Henry Xiang

Most machine learning models for predicting clinical outcomes are developed using historical data. Yet, even if these models are deployed in the near future, dataset shift over time may result in less than ideal performance. To capture this…

Machine Learning · Computer Science 2023-06-21 Christina X Ji , Ahmed M Alaa , David Sontag
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