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Different types of interactions coexist and coevolve to shape the structure and function of a multiplex network. We propose here a general class of growth models in which the various layers of a multiplex network coevolve through a set of…

Physics and Society · Physics 2014-10-15 Vincenzo Nicosia , Ginestra Bianconi , Vito Latora , Marc Barthelemy

In this study, we explore a mathematical model for tissue growth focusing on the interplay between multiple cell subpopulations with distinct phenotypic characteristics. The model addresses the dynamics of tissue growth influenced by…

Analysis of PDEs · Mathematics 2024-09-05 Tomasz Dębiec , Mainak Mandal , Markus Schmidtchen

A connection is established between discrete stochastic model describing microscopic motion of fluctuating cells, and macroscopic equations describing dynamics of cellular density. Cells move towards chemical gradient (process called…

Biological Physics · Physics 2010-05-18 Pavel M. Lushnikov , Nan Chen , Mark Alber

Nucleation and growth is the dominant relaxation mechanism driving first order phase transitions. In two-dimensional at systems nucleation has been applied to a wide range of problems in physics, chemistry and biology. Here we study…

Soft Condensed Matter · Physics 2016-03-09 Leopoldo R. Gomez , Nicolas A. Garcia , Vincenzo Vitelli , Jose Lorenzana , Daniel A. Vega

We investigate a class of Young diagrams growing via the addition of unit cells and satisfying the constraint that the height difference between adjacent columns $\geq r$. In the long time limit, appropriately re-scaled Young diagrams…

Statistical Mechanics · Physics 2021-06-09 P. L. Krapivsky

We study a simple growth model for (d+1)-dimensional films of binary alloys in which atoms are allowed to interact and equilibrate at the surface, but are frozen in the bulk. The resulting crystal is highly anisotropic: Correlations…

Statistical Mechanics · Physics 2009-10-28 Barbara Drossel , Mehran Kardar

Based on symmetry consideration of migration and shape deformations, we formulate phenomenologically the dynamics of cell crawling in two dimensions. Forces are introduced to change the cell shape. The shape deformations induce migration of…

Biological Physics · Physics 2016-03-23 Takao Ohta , Mitsusuke Tarama , Masaki Sano

Two phase solid-fluid mixture models are ubiquitous in biological applications. For instance, models for growth of tissues and biofilms combine time dependent and quasi-stationary boundary value problems set in domains whose boundary moves…

Analysis of PDEs · Mathematics 2024-01-17 Ana Carpio , Gema Duro

Growth patterns of complex systems predict how they change in sizes, numbers, masses, etc. Understanding growth is important, especially for many biological, ecological, urban, and socioeconomic systems. One noteworthy growth behavior is…

Physics and Society · Physics 2022-06-07 Jinkui Zhao

The Whittaker 2d growth model is a triangular continuous Markov diffusion process that appears in many scientific contexts. It has been theoretically intriguing to establish a large deviation principle for this 2d process with a scaling…

Probability · Mathematics 2020-09-29 Jun Gao , Jie Ding

We investigated the kinetics of domain growth on liposomes consisting of a ternary mixture (unsaturated phospholipid, saturated phospholipid, and cholesterol) by temperature jump. The domain growth process was monitored by fluorescence…

Soft Condensed Matter · Physics 2009-11-11 Daisuke Saeki , Tsutomu Hamada , Kenichi Yoshikawa

In order to describe two-dimensionally packed cells in epithelial tissues both mathematically and physically, there have been developed several sorts of geometrical models, such as the vertex model, the finite element model, the…

Biological Physics · Physics 2014-11-19 Yukitaka Ishimoto , Yoshihiro Morishita

In this paper we analyse a differential system related to a Glioblastoma growth. Using numerical simulations, we prove that model captures different kind of growth changing adequately the parameters of the model. Firstly, we make an…

Analysis of PDEs · Mathematics 2021-09-21 A. Fernández-Romero , F. Guillén-González , A. Suárez

Growth (and resorption) of biological tissue is formulated in the continuum setting. The treatment is macroscopic, rather than cellular or sub-cellular. Certain assumptions that are central to classical continuum mechanics are revisited,…

Quantitative Methods · Quantitative Biology 2015-06-26 K. Garikipati , E. M. Arruda , K. Grosh , H. Narayanan , S. Calve

Implant placement under soft tissues operation is described. In this operation tissues can reach such deformations that nonlinear properties are appeared. A mass-spring model modification for modeling nonlinear tissue operation is…

Numerical Analysis · Computer Science 2014-03-11 Sergei Nikolaev

This paper presents a real-time simulation involving ''protozoan-like'' cells that evolve by natural selection in a physical 2D ecosystem. Selection pressure is exerted via the requirements to collect mass and energy from the surroundings…

Neural and Evolutionary Computing · Computer Science 2023-05-23 Dylan Cope

The effects of a surfactant on two-dimensional pattern formation in epitaxial growth are explored theoretically using a simple model, in which an adatom becomes immobile only after overcoming a large energy barrier as it exchanges positions…

Condensed Matter · Physics 2016-08-31 Bang-Gui Liu , Jing Wu , E. G. Wang , Zhenyu Zhang

The mechanical properties of cells, which influence the properties of the tissue they belong to, are controlled by various mechanisms. Bi et al. theoretically demonstrated that density-independent rigidity transition occurs in…

Soft Condensed Matter · Physics 2018-02-27 H. Nogucci

In many tissues, cell type varies over single-cell length-scales, creating detailed spatial heterogeneities fundamental to physiological function. To gain understanding of this relationship between tissue function and detailed structure,…

The evolutionary transition to multicellularity transformed life on earth, allowing for the evolution of large, complex organisms. While multicellularity can be strongly advantageous, its earliest stages bring unique physical challenges.…