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The multiplicative decomposition model is widely employed for predicting residual stresses and morphologies of biological tissues due to growth. However, it relies on the assumption that the tissue is initially in a stress-free state, which…

Soft Condensed Matter · Physics 2020-09-04 Yangkun Du , Chaofeng Lü , Weiqiu Chen , Michel Destrade

Throughout developmental biology and ecology, transport can be driven by nonlocal interactions. Examples include cells that migrate based on contact with pseudopodia extended from other cells, and animals that move based on their vision of…

Pattern Formation and Solitons · Physics 2023-07-07 Thomas Jun Jewell , Andrew L. Krause , Philip K. Maini , Eamonn A. Gaffney

A hierarchical model for the growth of planar arch structures for RNA secondary structures is presented, and shown to be equivalent to a tree-growth model. Both models can be solved analytically, giving access to scaling functions for large…

Biomolecules · Quantitative Biology 2008-04-11 Francois David , Christian Hagendorf , Kay Joerg Wiese

Micropatterned substrates are often used to standardize cell experiments and to quantitatively study the relation between cell shape and function. Moreover, they are increasingly used in combination with traction force microscopy on soft…

Cell Behavior · Quantitative Biology 2015-06-19 Philipp J. Albert , Ulrich S. Schwarz

The paper discusses two models for non-overlapping finite line-segments constructed via the lilypond protocol, operating here on a given array of points in the plane with which are associated directions. At time 0, each line-segment starts…

Probability · Mathematics 2014-06-03 D. J. Daley , Sven Ebert , Günter Last

A main challenge in numerical simulations of moving contact line problems is that the adherence, or no-slip boundary condition leads to a non-integrable stress singularity at the contact line. In this report we perform the first steps in…

Fluid Dynamics · Physics 2015-10-23 Hanna Holmgren , Gunilla Kreiss

We study a tumor growth model in two space dimensions, where proliferation of the tumor cells leads to expansion of the tumor domain and migration of surrounding normal tissues into the exterior vacuum. The model features two moving…

Analysis of PDEs · Mathematics 2020-02-11 Inwon Kim , Jiajun Tong

A comprehensive modeling and simulation study of the first-order isotropic/smectic-A transition is presented and applied to phase diagram computation and two-dimensional spherulite growth. An approach based on nonlinear optimization, that…

Chemical Physics · Physics 2009-08-20 Nasser Mohieddin Abukhdeir , Alejandro D. Rey

We studied phase separation in a particle interacting system under a large drive along x. We here identify the basic growth mechanisms, and demonstrate time self-similarity, finite-size scaling, as well as other interesting features of both…

Statistical Mechanics · Physics 2009-11-07 Pablo I. Hurtado , J. Marro , E. V. Albano

The nucleation and propagation of disconnections play an essential role during twin growth. Atomistic methods can reveal such small structural features on twin facets and model their motion, yet are limited by the simulation length and time…

Materials Science · Physics 2025-06-06 Yang Hu , Dennis M. Kochmann , Brandon Runnels

This paper proposes a model for the growth two interacting populations of cells that do not mix. The dynamics is driven by pressure and cohesion forces on the one hand and proliferation on the other hand. Following earlier works on the…

Cell Behavior · Quantitative Biology 2018-04-12 Alina Chertock , Pierre Degond , Sophie Hecht , Jean-Paul Vincent

We propose general conditions for the emergence of Turing patterns in a domain that changes size through homogeneous growth/shrinkage based on the qualitative changes of a potential function. For this part of the work, we consider the most…

Pattern Formation and Solitons · Physics 2023-10-03 Aldo Ledesma-Durán

Surface growth is a crucial component of many natural and artificial processes from cell proliferation to additive manufacturing. In elastic systems surface growth is usually accompanied by the development of geometrical incompatibility…

Soft Condensed Matter · Physics 2019-05-08 Lev Truskinovsky , Giuseppe Zurlo

There is an unmet need for artificial intelligence techniques that can speed up the design of growth strategies for cultured tissues. Cultured tissue is increasingly important for a range of applications such as cultivated meat,…

Biological Physics · Physics 2025-08-04 Allison E. Andrews , Hugh Dickinson , James P. Hague

Monte Carlo simulations are employed to investigate the surface growth generated by deposition of particles of different sizes on a substrate, in one and two dimensions. The particles have a linear form, and occupy an integer number of…

Statistical Mechanics · Physics 2011-11-17 F. L. Forgerini , W. Figueiredo

We present and analyse a model for cell signalling processes in biological tissues. The model includes diffusion and nonlinear reactions on the cell surfaces, and both inter- and intracellular signalling. Using techniques from the theory of…

Analysis of PDEs · Mathematics 2020-03-12 Mariya Ptashnyk , Chandrasekhar Venkataraman

Computer simulations and scaling theory are used to investigate the damping of oscillations during epitaxial growth on high-symmetry surfaces. The crossover from smooth to rough growth takes place after the deposition of (D/F)^\delta…

Statistical Mechanics · Physics 2007-05-23 H. Kallabis , L. Brendel , P. Smilauer , J. Krug , D. E. Wolf

In this paper we address some modelling issues related to biological growth. Our treatment is based on a recently-proposed, general formulation for growth within the context of Mixture Theory (Journal of the Mechanics and Physics of Solids,…

Tissues and Organs · Quantitative Biology 2011-11-09 H. Narayanan , E. M. Arruda , K. Grosh , K. Garikipati

Collective cell motions underlie structure formation during embryonic development. Tissues exhibit emergent multicellular characteristics such as jamming, rigidity transitions, and glassy dynamics, but there remain questions about how those…

Biological Physics · Physics 2023-12-13 Evan Thomas , Sevan Hopyan

We consider an age-size structured cell population model based on the cell cycle length. The model is described by a first order partial differential equation with initial-boundary conditions. Using the theory of semigroups of positive…

Analysis of PDEs · Mathematics 2022-06-15 Katarzyna Pichór , Ryszard Rudnicki