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Nuclear magnetic resonance (NMR) spectroscopy provides an experimental readout of local chemical environments, but its use in molecular representation learning has been constrained by heterogeneous data and incomplete atom-level…

Chemical Physics · Physics 2026-05-12 Jiebin Fang , Zidi Yan , Churu Mao , Yongjun Jiang , Xinyi Tang , Lei Miao , Dan Lu , Yun Huang , Wanjing Ding , Zhongjun Ma

Super-resolution microscopy has catalyzed valuable insights into the sub-cellular, mechanistic details of many different biological processes across a wide range of cell types. Fluorescence polarization spectroscopy tools have also enabled…

Biological Physics · Physics 2023-01-25 Jack W Shepherd , Alex L Payne-Dwyer , Ji-Eun Lee , Aisha Syeda , Mark C Leake

Although efficient extraction of discriminative spatial-spectral features is critical for hyperspectral images classification (HSIC), it is difficult to achieve these features due to factors such as the spatial-spectral heterogeneity and…

Computer Vision and Pattern Recognition · Computer Science 2025-02-28 Yimin Zhu , Linlin Xu

Although 19F has high potential to serve as a background-free molecular marker in bioimaging, the molar amount of marker substance is often too small to enable 19F MR imaging or 19F NMR spectroscopy with a sufficiently high signal-to-noise…

Chemical Physics · Physics 2022-05-24 Johannes Bernarding , Christian Bruns , Isabell Prediger , Markus Plaumann

This paper presents a feature level fusion approach which uses the improved K-medoids clustering algorithm and isomorphic graph for face and palmprint biometrics. Partitioning around medoids (PAM) algorithm is used to partition the set of n…

Computer Vision and Pattern Recognition · Computer Science 2010-04-13 Dakshina Ranjan Kisku , Phalguni Gupta , Jamuna Kanta Sing

A novel technique based on machine learning is introduced to reconstruct the decays of highly Lorentz-boosted particles. Using an end-to-end deep learning strategy, the technique bypasses existing rule-based particle reconstruction methods…

High Energy Physics - Experiment · Physics 2023-10-04 CMS Collaboration

RSC is an essential chromatin remodeling factor that is required for the control of several processes including transcription, repair and replication. The ability of RSC to relocate centrally positioned mononucleosomes at the end of…

In single-molecule super-resolution microscopy, engineered point-spread functions (PSFs) are designed to efficiently encode new molecular properties, such as 3D orientation, into complex spatial features captured by a camera. To fully…

Image and Video Processing · Electrical Eng. & Systems 2019-07-16 Hesam Mazidi , Eshan S. King , Oumeng Zhang , Arye Nehorai , Matthew D. Lew

Multidimensional NMR spectroscopy is one of the basic tools for determining the structure of biomolecules. Unfortunately, the resolution of the spectra is often limited by inter-nuclear couplings. This limitation cannot be overcome by…

Predicting which proteins interact together from amino-acid sequences is an important task. We develop a method to pair interacting protein sequences which leverages the power of protein language models trained on multiple sequence…

Biomolecules · Quantitative Biology 2024-12-30 Umberto Lupo , Damiano Sgarbossa , Anne-Florence Bitbol

Two dimensional (2D) semiconductors present unique opportunities to intertwine optical and magnetic functionalities and to tune these performances through defects and dopants. Here, we integrate exciton pumping into a quantum sensing…

Accurate localization of proteins from fluorescence microscopy images is challenging due to the inter-class similarities and intra-class disparities introducing grave concerns in addressing multi-class classification problems. Conventional…

Computer Vision and Pattern Recognition · Computer Science 2021-10-11 Muhammad Tahir , Saeed Anwar , Ajmal Mian , Abdul Wahab Muzaffar

Fluorescence polarization microscopy images both the intensity and orientation of fluorescent dipoles, which plays a vital role in studying the molecular structure and dynamics of bio-complex. However, it is difficult to resolve the dipole…

Unsupervised person re-identification (Re-ID) aims to match pedestrian images from different camera views in unsupervised setting. Existing methods for unsupervised person Re-ID are usually built upon the pseudo labels from clustering.…

Computer Vision and Pattern Recognition · Computer Science 2022-06-08 Mingkun Li , Chun-Guang Li , Jun Guo

Light-activated drugs are a promising way to localize biological activity and minimize side effects. However, their development is complicated by the numerous photophysical and biological properties that must be simultaneously optimized. To…

Chemical Physics · Physics 2023-02-23 Simon Axelrod , Eugene Shakhnovich , Rafael Gómez-Bombarelli

Focusing electromagnetic energy to sub-wavelength dimensions has become an increasingly active field of research for a variety of applications such as Heat Assisted Magnetic Recording (HAMR), nanolithography, and nanoscale optical…

Weakly supervised semantic segmentation (WSSS) methods using class labels often rely on class activation maps (CAMs) to localize objects. However, traditional CAM-based methods struggle with partial activations and imprecise object…

Computer Vision and Pattern Recognition · Computer Science 2025-07-01 Dewen Zeng , Xinrong Hu , Yu-Jen Chen , Yawen Wu , Xiaowei Xu , Yiyu Shi

Designing protein sequences that fold into a target 3-D structure, termed as the inverse folding problem, is central to protein engineering. However, it remains challenging due to the vast sequence space and the importance of local…

Quantitative Methods · Quantitative Biology 2026-03-17 Sazan Mahbub , Souvik Kundu , Eric P. Xing

Photocontrol of reversibly switchable fluorescent proteins (RSFPs) was used to program optoacoustic signal time courses that were temporally unmixed to increase the proteins contrast-to-noise-ratios (CNRs) in optoacoustic imaging. In this…

A well-known diagnostic imaging modality, termed ultrasound tomography, was quickly developed for the detection of very small tumors whose sizes are smaller than the wavelength of the incident pressure wave without ionizing radiation,…

Medical Physics · Physics 2015-08-05 Tran Quang-Huy , Tran Duc-Tan , Huynh Huu Tue , Nguyen Linh-Trung