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In this paper, we study the problem of non-adaptive group testing, in which one seeks to identify which items are defective given a set of suitably-designed tests whose outcomes indicate whether or not at least one defective item was…

Information Theory · Computer Science 2025-09-26 Lan V. Truong , Matthew Aldridge , Jonathan Scarlett

We consider the nonadaptive group testing with N items, of which $K = \Theta(N^\theta)$ are defective. We study a test design in which each item appears in nearly the same number of tests. For each item, we independently pick L tests…

Information Theory · Computer Science 2018-09-26 Oliver Johnson , Matthew Aldridge , Jonathan Scarlett

The problem of detecting anomalies in multiple processes is considered. We consider a composite hypothesis case, in which the measurements drawn when observing a process follow a common distribution with an unknown parameter (vector), whose…

Information Theory · Computer Science 2020-04-22 Bar Hemo , Tomer Gafni , Kobi Cohen , Qing Zhao

We present a new optimization method for the group selection problem in linear regression. In this problem, predictors are assumed to have a natural group structure and the goal is to select a small set of groups that best fits the…

Methodology · Statistics 2024-04-23 Anant Mathur , Sarat Moka , Benoit Liquet , Zdravko Botev

Existing algorithms for subgroup discovery with numerical targets do not optimize the error or target variable dispersion of the groups they find. This often leads to unreliable or inconsistent statements about the data, rendering practical…

Artificial Intelligence · Computer Science 2017-07-06 Mario Boley , Bryan R. Goldsmith , Luca M. Ghiringhelli , Jilles Vreeken

The problem of quickest detection of an anomalous process among M processes is considered. At each time, a subset of the processes can be observed, and the observations from each chosen process follow two different distributions, depending…

Information Theory · Computer Science 2014-10-09 Kobi Cohen , Qing Zhao

The complete blood count (CBC) performed by automated hematology analyzers is one of the most ordered laboratory tests. It is a first-line tool for assessing a patient's general health status, or diagnosing and monitoring disease…

Machine Learning · Statistics 2020-11-25 Marta Avalos-Fernandez , Helene Touchais , Marcela Henriquez-Henriquez

Sequential detection of independent anomalous processes among K processes is considered. At each time, only M processes can be observed, and the observations from each chosen process follow two different distributions, depending on whether…

Information Theory · Computer Science 2023-07-19 Kobi Cohen , Qing Zhao

We consider the problem of detecting a small subset of defective items from a large set via non-adaptive "random pooling" group tests. We consider both the case when the measurements are noiseless, and the case when the measurements are…

Information Theory · Computer Science 2011-07-25 Chun Lam Chan , Pak Hou Che , Sidharth Jaggi , Venkatesh Saligrama

This paper addresses patient heterogeneity associated with prediction problems in biomedical applications. We propose a systematic hypothesis testing approach to determine the existence of patient subgroup structure and the number of…

Methodology · Statistics 2021-01-08 Xu Gao , Weining Shen , Jing Ning , Ziding Feng , Jianhua Hu

Optimization by stochastic gradient descent is an important component of many large-scale machine learning algorithms. A wide variety of such optimization algorithms have been devised; however, it is unclear whether these algorithms are…

Machine Learning · Computer Science 2014-02-26 Tom Schaul , Ioannis Antonoglou , David Silver

This paper provides a short introduction to the group testing problem, and reviews various aspects of its statistical physics formulation. Two main issues are discussed: the optimal design of pools used in a two-stage testing experiment,…

Statistical Mechanics · Physics 2009-11-13 Marc Mezard , Marco Tarzia , Cristina Toninelli

Group testing has its origin in the identification of syphilis in the US army during World War II. Much of the theoretical framework of group testing was developed starting in the late 1950s, with continued work into the 1990s. Recently,…

Other Statistics · Statistics 2017-07-27 Yaakov Malinovsky , Paul S. Albert

Up to date, only lower and upper bounds for the optimal configuration of a Square Array (A2) Group Testing (GT) algorithm are known. We establish exact analytical formulae and provide a couple of applications of our result. First, we…

Statistics Theory · Mathematics 2023-04-18 Ugnė Čižikovienė , Viktor Skorniakov

Subgroup analysis is a frequently used tool for evaluating heterogeneity of treatment effect and heterogeneity in treatment harm across observed baseline patient characteristics. While treatment efficacy and adverse event measures are often…

Applications · Statistics 2018-08-14 Nicholas C. Henderson , Ravi Varadhan

We describe a generalization of the group testing problem termed symmetric group testing. Unlike in classical binary group testing, the roles played by the input symbols zero and one are "symmetric" while the outputs are drawn from a…

Information Theory · Computer Science 2011-08-16 Amin Emad , Jun Shen , Olgica Milenkovic

We treat the statistical inference problems in which one needs to detect and estimate simultaneously using as small number of samples as possible. Conventional methods treat the detection and estimation subproblems separately, ignoring the…

Applications · Statistics 2014-11-07 Yasin Yilmaz , Shang Li , Xiaodong Wang

Non-adaptive group testing involves grouping arbitrary subsets of $n$ items into different pools. Each pool is then tested and defective items are identified. A fundamental question involves minimizing the number of pools required to…

Discrete Mathematics · Computer Science 2011-07-26 Mahdi Cheraghchi , Amin Karbasi , Soheil Mohajer , Venkatesh Saligrama

Statistical design of experiments is widely used in scientific and industrial investigations. A generalized minimum aberration (GMA) orthogonal array is optimum under the well-established, so-called GMA criterion, and such an array can…

Computation · Statistics 2021-04-27 Dursun A. Bulutoglu , Kenneth J. Ryan

We develop anytime-valid tests of invariance under the action of compact groups. The resulting test statistics are optimal in a logarithmic-growth sense. We apply our method to extend recent anytime-valid tests of independence and to…

Methodology · Statistics 2024-05-24 Tyron Lardy , Muriel Felipe Pérez-Ortiz