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We examine the role of complexity on arterial tree structures, determining globally optimal vessel arrangements using the Simulated AnneaLing Vascular Optimization (SALVO) algorithm, which we have previously used to reproduce features of…

Tissues and Organs · Quantitative Biology 2020-07-15 Jonathan Keelan , James P. Hague

The cerebral arteries are difficult to reproduce from first principles, featuring interwoven territories, and intricate layers of grey and white matter with differing metabolic demand. The aim of this study was to identify the ideal…

Medical Physics · Physics 2019-07-24 Jonathan Keelan , Emma M. L. Chung , James P. Hague

Understanding of vascular organization is a long-standing problem in quantitative biology and biophysics and is essential for the growth of large cultured tissues. Approaches are needed that (1) make predictions of optimal arteriovenous…

Tissues and Organs · Quantitative Biology 2023-08-25 James P. Hague

The understanding of the mechanisms driving vascular development is still limited. Techniques to generate vascular trees synthetically have been developed to tackle this problem. However, most algorithms are limited to single trees inside…

Biological Physics · Physics 2024-10-10 Etienne Jessen , Marc C. Steinbach , Dominik Schillinger

The three-dimensional vascular model reconstructed from CT images is widely used in medical diagnosis. At different phases, the beating of the heart can cause deformation of vessels, resulting in different vascular imaging states and false…

Computer Vision and Pattern Recognition · Computer Science 2024-10-11 Daosong Hu , Ruomeng Wang , Liang Zhao , Mingyue Cui , Song Ding , Kai Huang

We hereby present a full synthetic model, able to mimic the various constituents of the cerebral vascular tree, including the cerebral arteries, bifurcations and intracranial aneurysms. This model intends to provide a substantial dataset of…

Computer Vision and Pattern Recognition · Computer Science 2024-11-06 Rafic Nader , Florent Autrusseau , Vincent L'Allinec , Romain Bourcier

Significant intra-observer and inter-observer variability in the interpretation of coronary angiograms are reported. This variability is in part due to the common practices that rely on performing visual inspections by specialists (e.g.,…

Quantitative Methods · Quantitative Biology 2020-02-27 Babak Ravandi , Arash Ravandi

We build an evolutionary scenario that explains how some crucial physiological constraints in the arterial network of mammals - i.e. hematocrit, vessels diameters and arterial pressure drops - could have been selected by evolution. We…

Biological Physics · Physics 2014-05-22 Baptiste Moreau , Benjamin Mauroy

The diffusion of minimally invasive, endovascular interventions motivates the development of visualization methods for complex vascular networks. We propose a planar representation of blood vessel trees which preserves the properties that…

Image and Video Processing · Electrical Eng. & Systems 2025-10-23 Guillaume Houry , Tom Boeken , Stéphanie Allassonnière , Jean Feydy

The aortic vessel tree is composed of the aorta and its branching arteries, and plays a key role in supplying the whole body with blood. Aortic diseases, like aneurysms or dissections, can lead to an aortic rupture, whose treatment with…

Image and Video Processing · Electrical Eng. & Systems 2023-04-04 Yuan Jin , Antonio Pepe , Jianning Li , Christina Gsaxner , Fen-hua Zhao , Kelsey L. Pomykala , Jens Kleesiek , Alejandro F. Frangi , Jan Egger

Our ability to produce human-scale bio-manufactured organs is critically limited by the need for vascularization and perfusion. For tissues of variable size and shape, including arbitrarily complex geometries, designing and printing…

- Modeling Human cardiovascular system is always an important issue. One of the most effective methods is using lumped model to reach to a complete model of human cardiovascular system. Such modeling with advanced considerations is used in…

Simulated annealing (SA) was inspired from annealing in metallurgy, a technique involving heating and controlled cooling of a material to increase the size of its crystals and reduce their defects, both are attributes of the material that…

Optimization and Control · Mathematics 2014-01-21 Jiapu Zhang

Computed Tomography Coronary Angiography (CTCA) is a non-invasive method to evaluate coronary artery anatomy and disease. CTCA is ideal for geometry reconstruction to create virtual models of coronary arteries. To our knowledge there is no…

Computer Vision and Pattern Recognition · Computer Science 2022-11-04 Ramtin Gharleghi , Dona Adikari , Katy Ellenberger , Mark Webster , Chris Ellis , Arcot Sowmya , Sze-Yuan Ooi , Susann Beier

Mathematical models are widely recognized as a valuable tool for cardiovascular diagnosis and the study of circulatory diseases, especially to obtain data that require otherwise invasive measurements. To correctly simulate body…

Understanding time-dependent blood flow dynamics in arteries is crucial for diagnosing and treating cardiovascular diseases. However, accurately predicting time-varying flow patterns requires integrating observational data with…

Fluid Dynamics · Physics 2025-01-09 Muhammad Adnan Anwar , Jorge Tiago

Automatic labelling of anatomical structures, such as coronary arteries, is critical for diagnosis, yet existing (non-deep learning) methods are limited by a reliance on prior topological knowledge of the expected tree-like structures. As…

Image and Video Processing · Electrical Eng. & Systems 2024-03-05 Yadan Li , Mohammad Ali Armin , Simon Denman , David Ahmedt-Aristizabal

We report computational results of blood flow through a model of the human aortic arch and a vessel of actual diameter and length. On the top of the aortic arch the branching of the %%three arteries are included: the subclavian and jugular.…

Fluid Dynamics · Physics 2008-11-11 Renat A. Sultanov , Dennis Guster

Most machine learning-based coronary artery segmentation methods represent the vascular lumen surface in an implicit way by the centerline and the associated lumen radii, which makes the subsequent modeling process to generate a whole piece…

Computer Vision and Pattern Recognition · Computer Science 2016-06-10 Haoyin Zhou , James K. Min , Guanglei Xiong

Despite coronary artery calcium scoring being considered a largely solved problem within the realm of medical artificial intelligence, this paper argues that significant improvements can still be made. By shifting the focus from pathology…

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