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Alcohol consumption has been shown to influence cardiovascular mechanisms in humans, leading to observable alterations in the plasma metabolomic profile. Regression models are commonly employed to investigate these effects, treating…

Methodology · Statistics 2024-04-18 Yifan Yang , Chixiang Chen , Hwiyoung Lee , Ming Wang , Shuo Chen

For future surveys, spectroscopic follow-up for all supernovae will be extremely difficult. However, one can use light curve fitters, to obtain the probability that an object is a Type Ia. One may consider applying a probability cut to the…

Cosmology and Nongalactic Astrophysics · Physics 2014-10-24 Michelle Lochner , Bruce A. Bassett , Melvin Varughese , Renée Hlozek , Martin Kunz , Mat Smith , James Newling

Spectroscopic techniques are essential tools for determining the structure of molecules. Different spectroscopic techniques, such as Nuclear magnetic resonance (NMR), Infrared spectroscopy, and Mass Spectrometry, provide insight into the…

Chemical Physics · Physics 2024-10-30 Marvin Alberts , Oliver Schilter , Federico Zipoli , Nina Hartrampf , Teodoro Laino

This paper addresses the problem of separating spectral sources which are linearly mixed with unknown proportions. The main difficulty of the problem is to ensure the full additivity (sum-to-one) of the mixing coefficients and…

Methodology · Statistics 2010-08-30 Nicolas Dobigeon , Said Moussaoui , Jean-Yves Tourneret , Cedric Carteret

Molecular communication requires low-complexity symbol detection algorithms to deal with the many sources of uncertainty that are inherent in these channels. This paper proposes two variants of a high-performance asynchronous peak detection…

Information Theory · Computer Science 2017-02-27 Adam Noel , Andrew W. Eckford

We propose a Markov chain Monte Carlo-based deconvolution method designed to estimate the number of peaks in spectral data, along with the optimal parameters of each radial basis function. Assuming cases where the number of peaks is…

Methodology · Statistics 2021-02-04 Koki Okajima , Kenji Nagata , Masato Okada

Statistical models for proteomics data often estimate protein fold changes between two samples, A and B, as the average peptide intensity from sample A divided by the average peptide intensity from sample B. Such average intensity ratios…

Applications · Statistics 2015-07-27 Jonathon O'Brien , Harsha Gunawardena , Xian Chen , Joseph Ibrahim , Bahjat Qaqish

In this work, we develop and compare two innovative strategies for parameter estimation and radar detection of multiple point-like targets. The first strategy, which appears here for the first time, jointly exploits the maximum likelihood…

Signal Processing · Electrical Eng. & Systems 2020-12-02 Pia Addabbo , Jun Liu , Danilo Orlando , Giuseppe Ricci

This paper describes a new algorithm for hyperspectral image unmixing. Most of the unmixing algorithms proposed in the literature do not take into account the possible spatial correlations between the pixels. In this work, a Bayesian model…

Methodology · Statistics 2012-09-05 Olivier Eches , Nicolas Dobigeon , Jean-Yves Tourneret

Super-resolution imaging techniques have largely improved our capabilities to visualize nanometric structures in biological systems. Their application further enables one to potentially quantitate relevant parameters to determine the…

Biological Physics · Physics 2019-12-18 Tina Kosǔta , Marta Cullell-Dalmau , Francesca Cella Zanacchi , Carlo Manzo

Methods for unsupervised anomaly detection suffer from the fact that the data is unlabeled, making it difficult to assess the optimality of detection algorithms. Ensemble learning has shown exceptional results in classification and…

Machine Learning · Statistics 2016-10-26 Edward Yu , Parth Parekh

We present a powerful new algorithm that combines both spatial information (event locations and the point spread function) and spectral information (photon energies) to separate photons from overlapping sources. We use Bayesian statistical…

Instrumentation and Methods for Astrophysics · Physics 2017-11-06 David E. Jones , Vinay L. Kashyap , David A. van Dyk

This paper presents a multi-band image fusion algorithm based on unsupervised spectral unmixing for combining a high-spatial low-spectral resolution image and a low-spatial high-spectral resolution image. The widely used linear observation…

Computer Vision and Pattern Recognition · Computer Science 2016-11-03 Qi Wei , Jose Bioucas-Dias , Nicolas Dobigeon , Jean-Yves Tourneret , Marcus Chen , Simon Godsill

We develop a mixture-based approach to robust density modeling and outlier detection for experimental multivariate data that includes measurement error information. Our model is designed to infer atypical measurements that are not due to…

Astrophysics · Physics 2007-09-07 Jianyong Sun , Ata Kaban , Somak Raychaudhury

Spectral methods have emerged as a simple yet surprisingly effective approach for extracting information from massive, noisy and incomplete data. In a nutshell, spectral methods refer to a collection of algorithms built upon the eigenvalues…

Machine Learning · Statistics 2021-10-26 Yuxin Chen , Yuejie Chi , Jianqing Fan , Cong Ma

Source separation is one of the signal processing's main emerging domain. Many techniques such as maximum likelihood (ML), Infomax, cumulant matching, estimating function, etc. have been used to address this difficult problem.…

Mathematical Physics · Physics 2009-10-31 Ali Mohammad-Djafari

Mammalian cells have about 30,000-fold more protein molecules than mRNA molecules. This larger number of molecules and the associated larger dynamic range have major implications in the development of proteomics technologies. We examine…

Quantitative Methods · Quantitative Biology 2023-03-14 Michael J. MacCoss , Javier Alfaro , Meni Wanunu , Danielle A. Faivre , Nikolai Slavov

Network models provide a powerful framework for analysing single-cell count data, facilitating the characterisation of cellular identities, disease mechanisms, and developmental trajectories. However, uncertainty modeling in unsupervised…

Genomics · Quantitative Biology 2026-04-27 Shanshan Ren , Thomas E. Bartlett , Lina Gerontogianni , Swati Chandna

A multi-modal machine learning system uses multiple unique data sources and types to improve its performance. This article proposes a system that combines results from several types of models, all of which are trained on different data…

Machine Learning · Computer Science 2024-02-05 Aaron Mullen , Samuel E. Armstrong , Jasmine Perdeh , Bjorn Bauer , Jeffrey Talbert , V. K. Cody Bumgardner

Density level sets can be estimated using plug-in methods, excess mass algorithms or a hybrid of the two previous methodologies. The plug-in algorithms are based on replacing the unknown density by some nonparametric estimator, usually the…

Statistics Theory · Mathematics 2016-11-26 A. Rodríguez-Casal , P. Saavedra-Nieves