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The basic units in our brain are neurons and each neuron has more than 1000 synapse connections. Synapse is the basic structure for information transfer in an ever-changing manner, and short-term plasticity allows synapses to perform…

Materials Science · Physics 2014-03-05 Li Qiang Zhu , Chang Jin Wan , Li Qiang Guo , Yi Shi , Qing Wan

Individual locations of many neuronal cell bodies (>10^4) are needed to enable statistically significant measurements of spatial organization within the brain such as nearest-neighbor and microcolumnarity measurements. In this paper, we…

Biological Physics · Physics 2008-05-01 Andrew Inglis , Luis Cruz , Dan L. Roe , H. E. Stanley , Douglas L. Rosene , Brigita Urbanc

Edge detection (ED) is a fundamental perceptual process in computer vision, forming the structural basis for high-level reasoning tasks such as segmentation, recognition, and scene understanding. Despite substantial progress achieved by…

Computer Vision and Pattern Recognition · Computer Science 2026-02-12 Hao Shu

Representation learning on large-scale unstructured volumetric and surface meshes poses significant challenges in neuroimaging, especially when models must incorporate diverse vertex-level morphometric descriptors, such as cortical…

Computer Vision and Pattern Recognition · Computer Science 2026-04-08 Yujian Xiong , Mohammad Farazi , Yanxi Chen , Wenhui Zhu , Xuanzhao Dong , Natasha Lepore , Yi Su , Raza Mushtaq , Stephen Foldes , Andrew Yang , Yalin Wang

Deep learning has excelled in medical image classification, but its clinical application is limited by poor interpretability. Capsule networks, known for encoding hierarchical relationships and spatial features, show potential in addressing…

Computer Vision and Pattern Recognition · Computer Science 2024-11-05 Xinyu Geng , Jiaming Wang , Jun Xu

Human reasoning is grounded in an ability to identify highly abstract commonalities governing superficially dissimilar visual inputs. Recent efforts to develop algorithms with this capacity have largely focused on approaches that require…

Computer Vision and Pattern Recognition · Computer Science 2022-10-03 Taylor W. Webb , Shuhao Fu , Trevor Bihl , Keith J. Holyoak , Hongjing Lu

Many real-world mission-critical applications require continual online learning from noisy data and real-time decision making with a defined confidence level. Probabilistic models and stochastic neural networks can explicitly handle…

Disordered Systems and Neural Networks · Physics 2022-06-01 Sourav Dutta , Georgios Detorakis , Abhishek Khanna , Benjamin Grisafe , Emre Neftci , Suman Datta

The heterogeneity of neurological conditions, ranging from structural anomalies to functional impairments, presents a significant challenge in medical imaging analysis tasks. Moreover, the limited availability of well-annotated datasets…

Image and Video Processing · Electrical Eng. & Systems 2024-07-15 Yang Ma , Dongang Wang , Peilin Liu , Lynette Masters , Michael Barnett , Weidong Cai , Chenyu Wang

Neural connectomics has begun producing massive amounts of data, necessitating new analysis methods to discover the biological and computational structure. It has long been assumed that discovering neuron types and their relation to…

Neurons and Cognition · Quantitative Biology 2014-07-17 Eric Jonas , Konrad Kording

Accurately estimating the wiring diagram of a brain, known as a connectome, at an ultrastructure level is an open research problem. Specifically, precisely tracking neural processes is difficult, especially across many image slices. Here,…

Computer Vision and Pattern Recognition · Computer Science 2014-05-09 Ayushi Sinha , William Gray Roncal , Narayanan Kasthuri , Jeff W. Lichtman , Randal Burns , Michael Kazhdan

The vision-based grasping brain network integrates visual perception with cognitive and motor processes for visuomotor tasks. While invasive recordings have successfully decoded localized neural activity related to grasp type planning and…

Signal Processing · Electrical Eng. & Systems 2025-10-23 Anna Cetera , Sima Ghafoori , Ali Rabiee , Mohammad Hassan Farhadi , Yalda Shahriari , Reza Abiri

Human brains exhibit highly organized multiscale neurophysiological dynamics. Understanding those dynamic changes and the neuronal networks involved is critical for understanding how the brain functions in health and disease. Functional…

Neurons and Cognition · Quantitative Biology 2024-09-09 Manuel Morante , Kristian Frølich , Naveed ur Rehman

Despite their effective use in various fields, many aspects of neural networks are poorly understood. One important way to investigate the characteristics of neural networks is to explore the loss landscape. However, most models produce a…

Machine Learning · Computer Science 2022-04-12 Aleksandar Doknic , Torsten Möller

Large datasets often contain multiple distinct feature sets, or views, that offer complementary information that can be exploited by multi-view learning methods to improve results. We investigate anatomical multi-view data, where each brain…

Quantitative Methods · Quantitative Biology 2024-01-17 Yuxiang Wei , Yuqian Chen , Tengfei Xue , Leo Zekelman , Nikos Makris , Yogesh Rathi , Weidong Cai , Fan Zhang , Lauren J. O' Donnell

Current connectivity diagrams of human brain image data are either overly complex or overly simplistic. In this work we introduce simple yet accurate interactive visual representations of multiple brain image structures and the connectivity…

Graphics · Computer Science 2016-09-02 Saad Nadeem , Arie Kaufman

Ex-vivo MRI offers invaluable insights into the complexity of the human brain, enabling high-resolution anatomical delineation and integration with histopathology, and thus, contributes to both basic and clinical studies on normal and…

Quantitative Methods · Quantitative Biology 2024-12-25 Qinfeng Zhu , Sihui Li , Zuozhen Cao , Yao Shen , Haoan Xu , Guojun Xu , Haotian Li , Keqing Zhu , Zhiyong Zhao , Jing Zhang , Dan Wu

Detection and segmentation of the hippocampal structures in volumetric brain images is a challenging problem in the area of medical imaging. In this paper, we propose a two-stage 3D fully convolutional neural network that efficiently…

Computer Vision and Pattern Recognition · Computer Science 2019-02-13 Dengsheng Chen , Wenxi Liu , You Huang , Tong Tong , Yuanlong Yu

The Syncytial Mesh Model introduces a three-layered framework for large-scale brain dynamics integrating local neural circuitry, macrostructural connectivity, and a slow mesoscale control-field substrate associated with astrocytic syncytial…

Neurons and Cognition · Quantitative Biology 2026-05-18 Andreu Ballus Santacana

Interpretation and diagnosis of machine learning models have gained renewed interest in recent years with breakthroughs in new approaches. We present Manifold, a framework that utilizes visual analysis techniques to support interpretation,…

Machine Learning · Computer Science 2019-01-18 Jiawei Zhang , Yang Wang , Piero Molino , Lezhi Li , David S. Ebert