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The massively parallel nature of biological information processing plays an important role for its superiority to human-engineered computing devices. In particular, it may hold the key to overcoming the von Neumann bottleneck that limits…

The fundamental goal of Information Retrieval (IR) systems lies in their capacity to effectively satisfy human information needs - a challenge that encompasses not just the technical delivery of information, but the nuanced understanding of…

Information Retrieval · Computer Science 2025-04-15 Yashar Moshfeghi , Niall McGuire

Software-implementation, via neural networks, of brain-inspired computing approaches underlie many important modern-day computational tasks, from image processing to speech recognition, artificial intelligence and deep learning…

Optics · Physics 2021-02-19 J. Feldmann , N. Youngblood , C. D. Wright , H. Bhaskaran , W. H. P. Pernice

A growing body of work underlines striking similarities between biological neural networks and recurrent, binary neural networks. A relatively smaller body of work, however, discusses similarities between learning dynamics employed in deep…

Neural and Evolutionary Computing · Computer Science 2020-05-22 Jacques Kaiser , Hesham Mostafa , Emre Neftci

Continual learning is crucial for creating AI agents that can learn and improve themselves autonomously. A primary challenge in continual learning is to learn new tasks without losing previously learned knowledge. Current continual learning…

Machine Learning · Computer Science 2025-03-18 Amin Banayeeanzade , Mohammad Rostami

Large-scale cell microscopy screens are used in drug discovery and molecular biology research to study the effects of millions of chemical and genetic perturbations on cells. To use these images in downstream analysis, we need models that…

Every year, millions of brain MRI scans are acquired in hospitals, which is a figure considerably larger than the size of any research dataset. Therefore, the ability to analyse such scans could transform neuroimaging research. Yet, their…

Image and Video Processing · Electrical Eng. & Systems 2023-03-29 Benjamin Billot , Colin Magdamo , You Cheng , Steven E. Arnold , Sudeshna Das , Juan. E. Iglesias

Visual data is used in numerous different scientific workflows ranging from remote sensing to ecology. As the amount of observation data increases, the challenge is not just to make accurate predictions but also to understand the underlying…

Computer Vision and Pattern Recognition · Computer Science 2025-02-17 Utkarsh Mall , Cheng Perng Phoo , Mia Chiquier , Bharath Hariharan , Kavita Bala , Carl Vondrick

Skull-stripping is the removal of background and non-brain anatomical features from brain images. While many skull-stripping tools exist, few target pediatric populations. With the emergence of multi-institutional pediatric data acquisition…

Image and Video Processing · Electrical Eng. & Systems 2025-12-05 William Kelley , Nathan Ngo , Adrian V. Dalca , Bruce Fischl , Lilla Zöllei , Malte Hoffmann

Brain network analysis is a useful approach to studying human brain disorders because it can distinguish patients from healthy people by detecting abnormal connections. Due to the complementary information from multiple modal neuroimages,…

Image and Video Processing · Electrical Eng. & Systems 2023-08-22 Qiankun Zuo , Yanfei Zhu , Libin Lu , Zhi Yang , Yuhui Li , Ning Zhang

Automating the extraction and quantification of features from three-dimensional (3-D) image stacks is a critical task for advancing computer vision research. The union of 3-D image acquisition and analysis enables the quantification of…

Computer Vision and Pattern Recognition · Computer Science 2017-04-11 P. Saponaro , W. Treible , A. Kolagunda , S. Rhein , J. Caplan , C. Kambhamettu , R. Wisser

Electroencephalogram (EEG) decoding is a critical component of medical diagnostics, rehabilitation engineering, and brain-computer interfaces. However, contemporary decoding methodologies remain heavily dependent on task-specific datasets…

Human-Computer Interaction · Computer Science 2026-01-27 Siyang Li , Zhuoya Wang , Xiyan Gui , Xiaoqing Chen , Ziwei Wang , Yaozhi Wen , Dongrui Wu

Recently deep residual learning with residual units for training very deep neural networks advanced the state-of-the-art performance on 2D image recognition tasks, e.g., object detection and segmentation. However, how to fully leverage…

Computer Vision and Pattern Recognition · Computer Science 2016-08-23 Hao Chen , Qi Dou , Lequan Yu , Pheng-Ann Heng

Segmenting the retinal vasculature entails a trade-off between how much of the overall vascular structure we identify vs. how precisely we segment individual vessels. In particular, state-of-the-art methods tend to under-segment faint…

Computer Vision and Pattern Recognition · Computer Science 2019-03-28 Aashis Khanal , Rolando Estrada

Deep convolutional neural networks are powerful tools for learning visual representations from images. However, designing efficient deep architectures to analyse volumetric medical images remains challenging. This work investigates…

Computer Vision and Pattern Recognition · Computer Science 2017-07-10 Wenqi Li , Guotai Wang , Lucas Fidon , Sebastien Ourselin , M. Jorge Cardoso , Tom Vercauteren

The intricate morphology of brain vessels poses significant challenges for automatic segmentation models, which usually focus on a single imaging modality. However, accurately treating brain-related conditions requires a comprehensive…

Computer Vision and Pattern Recognition · Computer Science 2025-10-03 Francesco Galati , Daniele Falcetta , Rosa Cortese , Ferran Prados , Ninon Burgos , Maria A. Zuluaga

Mapping the connectivity of neurons in the brain (i.e., connectomics) is a challenging problem due to both the number of connections in even the smallest organisms and the nanometer resolution required to resolve them. Because of this,…

Neurons and Cognition · Quantitative Biology 2014-09-08 Ting Zhao , Stephen M Plaza

Pathological brain appearances may be so heterogeneous as to be intelligible only as anomalies, defined by their deviation from normality rather than any specific pathological characteristic. Amongst the hardest tasks in medical imaging,…

Image and Video Processing · Electrical Eng. & Systems 2021-02-24 Walter Hugo Lopez Pinaya , Petru-Daniel Tudosiu , Robert Gray , Geraint Rees , Parashkev Nachev , Sebastien Ourselin , M. Jorge Cardoso

Human brain connectome studies aim at extracting and analyzing relevant features associated to pathologies of interest. Usually this consists in modeling the brain connectome as a graph and in using graph metrics as features. A fine brain…

Neurons and Cognition · Quantitative Biology 2020-05-04 Félix Renard , Christian Heinrich , Marine Bouthillon , Maleka Schenck , Francis Schneider , Stéphane Kremer , Sophie Achard

Molecular biology knowledge can be systematically represented in a computer-readable form as a comprehensive map of molecular interactions. There exist a number of maps of molecular interactions containing detailed description of various…

Molecular Networks · Quantitative Biology 2015-02-03 Inna Kuperstein , David PA Cohen , Stuart Pook , Laurence Calzone , Emmanuel Barillot , Andrei Zinovyev
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