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The prediction plays the important role in detecting efficient protection and therapy of cancer. The prediction of mutations in gene needs a diagnostic and classification, which is based on the whole database (big dataset), to reach…

Machine Learning · Computer Science 2016-08-10 Ayad Ghany Ismaeel , Dina Yousif Mikhail

In recent era prediction of enzyme class from an unknown protein is one of the challenging tasks in bioinformatics. Day to day the number of proteins is increases as result the prediction of enzyme class gives a new opportunity to…

Machine Learning · Computer Science 2019-01-21 Chhote Lal Prasad Gupta , Anand Bihari , Sudhakar Tripathi

Data mining is the task of discovering interesting patterns from large amounts of data. There are many data mining tasks, such as classification, clustering, association rule mining, and sequential pattern mining. Sequential pattern mining…

Databases · Computer Science 2010-02-08 Mahdi Esmaeili , Fazekas Gabor

Proteins play crucial roles in every cellular process by interacting with each other, with nucleic acids, metabolites, and other molecules. The resulting assemblies can be very large and intricate and pose challenges to experimental…

Biomolecules · Quantitative Biology 2021-03-16 Charlotte W. van Noort , Rodrigo V. Honorato , Alexandre M. J. J. Bonvin

Deep learning is catalyzing a scientific revolution fueled by big data, accessible toolkits, and powerful computational resources, impacting many fields including protein structural modeling. Protein structural modeling, such as predicting…

Biomolecules · Quantitative Biology 2020-07-17 Wenhao Gao , Sai Pooja Mahajan , Jeremias Sulam , Jeffrey J. Gray

Now-a-days the amount of data stored in educational database increasing rapidly. These databases contain hidden information for improvement of students' performance. Educational data mining is used to study the data available in the…

Machine Learning · Computer Science 2012-03-20 Surjeet Kumar Yadav , Saurabh Pal

Classification is one of the major issues in Data Mining Research fields. The classification problems in medical area often classify medical dataset based on the result of medical diagnosis or description of medical treatment by the medical…

Artificial Intelligence · Computer Science 2013-01-09 N. Kalaiselvi , H. Hannah Inbarani

Accurately modeling the protein fitness landscapes holds great importance for protein engineering. Recently, due to their capacity and representation ability, pre-trained protein language models have achieved state-of-the-art performance in…

Biomolecules · Quantitative Biology 2024-02-06 Ziyi Zhou , Liang Zhang , Yuanxi Yu , Mingchen Li , Liang Hong , Pan Tan

In recent years, there have been unprecedented technological advances in sensor technology, and sensors have become more affordable than ever. Thus, sensor-driven data collection is increasingly becoming an attractive and practical option…

Machine Learning · Computer Science 2021-12-30 Alireza Abdoli

In this work we set out to find a method to classify protein structures using a Deep Learning methodology. Our Artificial Intelligence has been trained to recognize complex biomolecule structures extrapolated from the Protein Data Bank…

Machine Learning · Computer Science 2021-11-04 Damiano Perri , Marco Simonetti , Andrea Lombardi , Noelia Faginas-Lago , Osvaldo Gervasi

Systematic identification of protein function is a key problem in current biology. Most traditional methods fail to identify functionally equivalent proteins if they lack similar sequences, structural data or extensive manual annotations.…

Genomics · Quantitative Biology 2016-03-08 Dan Ofer

Proteins, essential to biological systems, perform functions intricately linked to their three-dimensional structures. Understanding the relationship between protein structures and their amino acid sequences remains a core challenge in…

Quantitative Methods · Quantitative Biology 2024-11-04 Liang He , Peiran Jin , Yaosen Min , Shufang Xie , Lijun Wu , Tao Qin , Xiaozhuan Liang , Kaiyuan Gao , Yuliang Jiang , Tie-Yan Liu

MOTIVATION: Proteins fold into complex structures that are crucial for their biological functions. Experimental determination of protein structures is costly and therefore limited to a small fraction of all known proteins. Hence, different…

Biomolecules · Quantitative Biology 2018-04-18 David Menéndez Hurtado , Karolis Uziela , Arne Elofsson

Enzyme mining is rapidly evolving as a data-driven strategy to identify biocatalysts with tailored functions from the vast landscape of uncharacterized proteins. The integration of machine learning into these workflows enables…

Biomolecules · Quantitative Biology 2025-07-11 Yanzi Zhang , Felix Moorhoff , Sizhe Qiu , Wenjuan Dong , David Medina-Ortiz , Jing Zhao , Mehdi D. Davari

In the 21st-century information age, with the development of big data technology, effectively extracting valuable information from massive data has become a key issue. Traditional data mining methods are inadequate when faced with…

Computer Vision and Pattern Recognition · Computer Science 2024-11-28 Aoran Shen , Minghao Dai , Jiacheng Hu , Yingbin Liang , Shiru Wang , Junliang Du

In intrusion detection systems, classifiers still suffer from several drawbacks such as data dimensionality and dominance, different network feature types, and data impact on the classification. In this paper two significant enhancements…

Cryptography and Security · Computer Science 2012-12-12 Maher Salem , Ulrich Buehler

Composed of amino acid chains that influence how they fold and thus dictating their function and features, proteins are a class of macromolecules that play a central role in major biological processes and are required for the structure,…

Quantitative Methods · Quantitative Biology 2022-07-15 Aaron Wang

Machine learning (ML) approaches have been used to develop highly accurate and efficient applications in many fields including bio-medical science. However, even with advanced ML techniques, cancer classification using gene expression data…

Genomics · Quantitative Biology 2023-05-10 Mahmood Khalsan , Mu Mu , Eman Salih Al-Shamery , Lee Machado , Suraj Ajit , Michael Opoku Agyeman

After data selection, pre-processing, transformation, and feature extraction, knowledge extraction is not the final step in a data mining process. It is then necessary to understand this knowledge in order to apply it efficiently and…

Machine Learning · Computer Science 2016-05-23 Dominik Fisch , Christian Gruhl , Edgar Kalkowski , Bernhard Sick , Seppo J. Ovaska

One of the important techniques of Data mining is Classification. Many real world problems in various fields such as business, science, industry and medicine can be solved by using classification approach. Neural Networks have emerged as an…

Machine Learning · Computer Science 2011-10-13 K. Usha Rani