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Photoacoustic computed tomography (PACT) is an emerging computed imaging modality that exploits optical contrast and ultrasonic detection principles to form images of the absorbed optical energy density within tissue. If the object…

Medical Physics · Physics 2017-09-08 Joemini Poudel , Thomas P. Matthews , Lei Li , Mark A. Anastasio , Lihong V. Wang

Reconstruction of ultrasound (US) images from radio-frequency data can be conceptualized as a linear inverse problem. Traditional deep learning approaches, which aim to improve the quality of US images by directly learning priors, often…

Computer Vision and Pattern Recognition · Computer Science 2023-12-18 Zhiqiang Li , Hengrong Lan , Lijie Huang , Qiong He , Jianwen Luo

Quantitative image reconstruction in photoacoustic tomography requires the solution of a coupled physics inverse problem involvier light transport and acoustic wave propagation. In this paper we address this issue employing the radiative…

Analysis of PDEs · Mathematics 2017-02-16 Markus Haltmeier , Lukas Neumann , Linh V. Nguyen , Simon Rabanser

Ultrasound-modulated optical tomography is an emerging biomedical imaging modality which uses the spatially localised acoustically-driven modulation of coherent light as a probe of the structure and optical properties of biological tissues.…

Medical Physics · Physics 2016-03-22 Samuel Powell , Simon R. Arridge , Terence S. Leung

Extracting as much information as possible about an object when probing with a limited number of photons is an important goal with applications from biology and security to metrology. Imaging with a few photons is a challenging task as the…

In deep tissue photoacoustic imaging the spatial resolution is inherently limited by the acoustic wavelength. Recently, it was demonstrated that it is possible to surpass the acoustic diffraction limit by analyzing fluctuations in a set of…

Diffusion coefficient measurements are important for many biological and material investigations, such as particle dynamics, kinetics, and size determinations. Amongst current measurement methods, single particle tracking (SPT) offers the…

Biomolecules · Quantitative Biology 2011-07-12 Shannon Kian Zareh , Michael C. DeSantis , Jonathan Kessler , Je-Luen Li , Y. M. Wang

Photoacoustic tomography (PAT) is a medical imaging modality that can provide high-resolution tissue images based on the optical absorption. Classical reconstruction methods for quantifying the absorption coefficients rely on sufficient…

Image and Video Processing · Electrical Eng. & Systems 2026-04-24 Anssi Manninen , Janek Gröhl , Felix Lucka , Andreas Hauptmann

Quantitative photoacoustic tomography (qPAT) is an imaging technique aimed at estimating chromophore concentrations inside tissues from photoacoustic images, which are formed by combining optical information and ultrasonic propagation. The…

Computational Physics · Physics 2019-12-23 Hwan Goh , Timo Lahivaara , Tanja Tarvainen , Aki Pulkkinen , Owen Dillon , Ruanui Nicholson , Jari Kaipio

Real-time monitoring of functional tissue parameters, such as local blood oxygenation, based on optical imaging could provide groundbreaking advances in the diagnosis and interventional therapy of various diseases. While photoacoustic (PA)…

Medical Physics · Physics 2018-08-15 Thomas Kirchner , Janek Gröhl , Lena Maier-Hein

In photoacoustic imaging, ultrasound waves generated by a temperature rise after illumination of light absorbing structures are measured on the sample surface. These measurements are then used to reconstruct the optical absorption. We…

Applied Physics · Physics 2018-12-05 Oliver Lang , Peter Kovacs , Christian Motz , Mario Huemer , Thomas Berer , Peter Burgholzer

The paper introduces the idea of non-uniform quantization in the detail components of wavelet transformed image. It argues that most of the coefficients of horizontal, vertical and diagonal components lie near to zeros and the coefficients…

Multimedia · Computer Science 2013-06-13 Madhur Srivastava , Prasanta K. Panigrahi

This paper analyzes the reconstruction of diffusion and absorption parameters in an elliptic equation from knowledge of internal data. In the application of photo-acoustics, the internal data are the amount of thermal energy deposited by…

Analysis of PDEs · Mathematics 2015-05-14 Guillaume Bal , Gunther Uhlmann

Photoacoustic computed tomography (PACT), also known as optoacoustic tomography, is an emerging imaging technique that holds great promise for biomedical imaging. PACT is a hybrid imaging method that can exploit the strong endogenous…

Medical Physics · Physics 2019-05-13 Joemini Poudel , Yang Lou , Mark A. Anastasio

We are concerned with the inverse scattering problem of recovering an inhomogeneous medium by the associated acoustic wave measurement. We prove that under certain assumptions, a single far-field pattern determines the values of a…

Analysis of PDEs · Mathematics 2020-05-05 Emilia Blåsten , Hongyu Liu

Photoacoustic tomography is a hybrid imaging technique that combines high optical tissue contrast with high ultrasound resolution. Direct reconstruction methods such as filtered backprojection, time reversal and least squares suffer from…

Forward and adjoint Monte Carlo (MC) models of radiance are proposed for use in model-based quantitative photoacoustic tomography. A 2D radiance MC model using a harmonic angular basis is introduced and validated against analytic solutions…

Medical Physics · Physics 2016-12-21 Roman Hochuli , Samuel Powell , Simon Arridge , Ben Cox

In photoacoustic tomography (PAT), a hybrid imaging modality that is based on the acoustic detection of optical absorption from biological tissue exposed to a pulsed laser, a short pulse laser generates an initial pressure proportional to…

Numerical Analysis · Mathematics 2026-03-27 Sunghwan Moon , Anwesa Dey , Souvik Roy

We are concerned with an inverse problem associated with the fractional Helmholtz system that arises from the study of viscoacoustics in geophysics and thermoviscous modelling of lossy media. We are particularly interested in the case that…

Analysis of PDEs · Mathematics 2018-03-28 Xinlin Cao , Hongyu Liu

The aim of this paper is to put the problem of vibroacoustic imaging into the mathematical framework of inverse problems (more precisely, coefficient identification in PDEs) and regularization. We present a model in frequency domain, prove…

Analysis of PDEs · Mathematics 2021-09-07 Barbara Kaltenbacher