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The biological membrane, which compartmentalizes the cell and its organelles, exhibit wide variety of macroscopic shapes of varying morphology and topology. A systematic understanding of the relation of membrane shapes to composition,…

Biological Physics · Physics 2011-09-23 N. Ramakrishnan , P. B. Sunil Kumar , John H. Ipsen

The task of learning patterns is typically associated with systems that update parameters on fixed architectures, such as neural networks, where learning proceeds through continuous optimization. Here, we demonstrate that pattern learning…

Disordered Systems and Neural Networks · Physics 2026-04-29 Shabeeb Ameen , Tao Zhang , J. M. Schwarz

This work concerns a structural topology optimisation problem for 4D printing based on the phase field approach. The concept of 4D printing as a targeted evolution of 3D printed structures can be realised in a two-step process. One first…

Optimization and Control · Mathematics 2023-05-03 Harald Garcke , Kei Fong Lam , Robert Nürnberg , Andrea Signori

The topology and form finding of tensegrity structures have been studied extensively since the introduction of the tensegrity concept. However, most of these studies address topology and form separately, where the former represented a…

Computational Geometry · Computer Science 2019-02-27 Omar Aloui , Jessica Flores , David Orden , Landolf Rhode-Barbarigos

A macro-constitutive model for the deformation response of periodic rotating bistable auxetic surfaces is developed. Focus is placed on isotropic surfaces made of bistable hexagonal cells composed of six triangular units with two stable…

Applied Physics · Physics 2025-12-01 Emmanuel Sansusthy Tardio , Tian Chen , Theocharis Baxevanis

While the behavior of vesicles in thermodynamic equilibrium has been studied extensively, how active forces control vesicle shape transformations is not understood. Here, we combine theory and simulations to study the shape behavior of…

Soft Condensed Matter · Physics 2019-10-09 Yao Li , Pieter Rein ten Wolde

Epithelial tissues play a fundamental role in various morphogenetic events during development and early embryogenesis. Although epithelial monolayers are often modeled as two-dimensional (2D) elastic surfaces, they distinguish themselves…

Soft Condensed Matter · Physics 2020-06-15 Benjamin Loewe , Francesco Serafin , Suraj Shankar , Mark J. Bowick , M. Cristina Marchetti

The macroscopic behaviour of active matter arises from nonequilibrium microscopic processes. In soft materials, active stresses typically drive macroscopic shape changes, which in turn alter the geometry constraining the microscopic…

Soft Condensed Matter · Physics 2024-11-26 Tim Dullweber , Roman Belousov , Anna Erzberger

In embryonic development, programmed cell shape changes are essential for building functional organs, but in many cases the mechanisms that precisely regulate these changes remain unknown. We propose that fluid-like drag forces generated by…

Biological Physics · Physics 2019-01-03 Gonca Erdemci-Tandogan , Madeline J. Clark , Jeffrey D. Amack , M. Lisa Manning

The folding of cellular monolayers pervades embryonic development and disease. It results from stresses out of the plane of the tissue, often caused by cell shape changes including cell wedging via apical constriction. These local cellular…

Soft Condensed Matter · Physics 2025-12-12 Pierre A. Haas , Stephanie S. M. H. Höhn

This paper contains a thorough investigation of the performance of electrically activated layered soft dielectric composite actuators under plane deformation. Noting that the activation can be induced controlling either the voltage or the…

Soft Condensed Matter · Physics 2015-06-17 Massimiliano Gei , Roberta Springhetti , Eliana Bortot

This study investigates the coupled deformation and flow behavior of thin, hyper-elastic, porous membranes subjected to pressure loading. Using bulge test experiments, optical deformation measurements, and flow rate characterization, we…

Fluid Dynamics · Physics 2026-01-19 Alexander Gehrke , Zoe King , Kenneth S. Breuer

Capturing the emergence of deformation waves in contractile living tissues is a challenge that has recently been tackled with models of actively deformable particles. Inspired by the anisotropic deformation of cardiomyocytes in cardiac…

Soft Condensed Matter · Physics 2026-05-26 Luca Casagrande , Alessandro Manacorda , Etienne Fodor

The multi-scale nature of architectured materials raises the need for advanced experimental methods suitable for the identification of their effective properties, especially when their size is finite and they undergo extreme deformations.…

Applied Physics · Physics 2024-03-04 Filippo Agnelli , Pierre Margerit , Paolo Celli , Chiara Daraio , Andrei Constantinescu

Many organisms have an elastic skeleton that consists of a closed shell of epithelial cells that is filled with fluid, and can actively regulate both elastic forces in the shell and hydrostatic pressure inside it. In this work we introduce…

Soft Condensed Matter · Physics 2023-10-13 Ajoy Maji , Yitzhak Rabin

The complexity of a neuronal cell shape is known to be related to its function. Specifically, among other indicators, a decreased complexity in the dendritic trees of cortical pyramidal neurons has been associated with mental retardation.…

Quantitative Methods · Quantitative Biology 2007-05-23 M. S. Barbosa , L. da F. Costa , E. S. Bernardes , G. Ramakers , J. van Pelt

Living systems are capable of locomotion, reconfiguration, and replication. To perform these tasks, cells spatiotemporally coordinate the interactions of force-generating, "active" molecules that create and manipulate non-equilibrium…

Soft Condensed Matter · Physics 2019-08-28 Tyler D. Ross , Heun Jin Lee , Zijie Qu , Rachel A. Banks , Rob Phillips , Matt Thomson

A new approach for generating stress-constrained topological designs in continua is presented. The main novelty is in the use of elasto-plastic modeling and in optimizing the design such that it will exhibit a linear-elastic response. This…

Computational Engineering, Finance, and Science · Computer Science 2016-08-25 Oded Amir

We introduce a computational framework for the topology optimization of cellular structures with spatially varying architecture, which is applied to functionally graded truss lattices under quasistatic loading. We make use of a first-order…

Other Condensed Matter · Physics 2022-05-31 Bastian Telgen , Ole Sigmund , Dennis M. Kochmann

Jammed packings of granular materials display complex mechanical response. For example, the ensemble-averaged shear modulus $\left\langle G \right\rangle$ increases as a power-law in pressure $p$ for static packings of soft spherical…

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