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To swim through a viscous fluid, a flagellated bacterium must overcome the fluid drag on its body by rotating a flagellum or a bundle of multiple flagella. Because the drag increases with the size of bacteria, it is expected theoretically…

We aim to understand the formation of abnormal waves of activity from myocardial regions with diminished cell-to-cell coupling. In route to this goal, we studied the behavior of a heterogeneous myocyte network in which a sharp coupling…

Tissues and Organs · Quantitative Biology 2009-11-13 V. N. Biktashev , A. Arutunyan , N. A. Sarvazyan

Many active biological particles, such as swimming microorganisms or motor-proteins, do work on their environment by going though a periodic sequence of shapes. Interactions between particles can lead to the phase-synchronization of their…

Soft Condensed Matter · Physics 2022-07-26 Brato Chakrabarti , Michael J. Shelley , Sebastian Fürthauer

Life in complex systems, such as cities and organisms, comes to a standstill when global coordination of mass, energy, and information flows is disrupted. Global coordination is no less important in single cells, especially in large oocytes…

Proper heart morphogenesis requires a delicate balance between hemodynamic forces, myocardial activity, morphogen gradients, and epigenetic signaling, all of which are coupled with genetic regulatory networks. Recently both in vivo and in…

Tissues and Organs · Quantitative Biology 2018-09-19 Nicholas A. Battista , Dylan R. Douglas , Andrea N. Lane , Leigh Ann Samsa , Jiandong Liu , Laura A. Miller

Marine microorganisms must cope with complex flow patterns and even turbulence as they navigate the ocean. To survive they must avoid predation and find efficient energy sources. A major difficulty in analysing possible survival strategies…

Fluid Dynamics · Physics 2022-11-29 J. Qiu , N. Mousavi , K. Gustavsson , C. Xu , B. Mehlig , L. Zhao

Liquid-liquid phase separation is important across biology, physics, and materials science. Although usually studied at equilibrium, active components - such as motor proteins, enzymes, and synthetic microswimmers - are increasingly…

Soft Condensed Matter · Physics 2026-01-06 Kan Chang , Yulin Li , Ming Yuan , Masaki Sano , Zhihong You , H. P. Zhang

Hydrodynamic interactions are crucial for determining the cooperative behavior of microswimmers at low Reynolds numbers. Here we provide a comprehensive analysis of the scaling and strength of the interactions in the case of a pair of…

Soft Condensed Matter · Physics 2021-02-11 Sebastian Ziegler , Thomas Scheel , Maxime Hubert , Jens Harting , Ana-Sunčana Smith

Navigation of microorganisms is controlled by internal processes ultimately sensitive to mechanical or chemical signaling encountered along the path. In many natural environments, such as porous soils or physiological ducts, motile species…

Understanding the collective actuation of microscopic structures driven by external fields can lead to the development of next-generation autonomous machines. With this goal in mind, we investigated light-induced collective motion of…

Sperm modulate their flagellar symmetry to navigate through complex physico-chemical environments and achieve reproductive function. Yet it remains elusive how sperm swim forwards despite the inherent asymmetry of several components that…

Biological Physics · Physics 2023-07-21 Xiaomeng Ren , Hermes Bloomfield-Gadêlha

Motile cilia drive biological fluid transport through whip-like beating motions that synchronize into metachronal waves. The lengths of these cilia span three orders of magnitude, from microns in human airways to millimeters in ctenophores.…

Aims. Qualitative analysis of key (but yet unappreciated) linear phenomena in stratified hydrodynamic Keplerian flows: (i) the occurrence of a vortex mode, as a consequence of strato-rotational balance, with its transient dynamics; (ii) the…

Astrophysics · Physics 2009-11-13 A. G. Tevzadze , G. D. Chagelishvili , J. -P. Zahn

The flexibility of the bacterial flagellar hook is believed to have substantial consequences for microorganism locomotion. Using a simplified model of a rigid flagellum and a flexible hook, we show that the paths of axisymmetric cell bodies…

Biological Physics · Physics 2021-10-28 Zonghao Zou , Wilson Lough , Saverio E. Spagnolie

In nature, many unicellular organisms are able to swim with the help of beating filaments, where local energy input leads to cooperative undulatory beating motion. Here, we investigate by employing reinforcement learning how undulatory…

Biological Physics · Physics 2025-11-04 Fumiya Tokoro , Hideki Takayama , Shinji Deguchi , Andreas Zöttl , Daiki Matsunaga

Many eukaryotic cells use the active waving motion of flexible flagella to self-propel in viscous fluids. However, the criteria governing the selection of particular flagellar waveforms among all possible shapes has proved elusive so far.…

Biological Physics · Physics 2013-08-02 Christophe Eloy , Eric Lauga

Despite their vast morphological diversity, many invertebrates have similar larval forms characterized by ciliary bands, innervated arrays of beating cilia that facilitate swimming and feeding. Hydrodynamics suggests that these bands should…

Fluid Dynamics · Physics 2018-04-25 William Gilpin , Vivek N. Prakash , Manu Prakash

The course of a peritrichous bacterium such as E. coli crucially depends on the level of synchronization and self-organization of several rotating flagella. However, the rotation of each flagellum generates counter body movements which in…

Biological Physics · Physics 2015-11-11 Tapan Chandra Adhyapak , Holger Stark

Cilia and flagella are hairlike organelles that propel cells through fluid. The active motion of the axoneme, the motile structure inside cilia and flagella, is powered by molecular motors of the dynein family. These motors generate forces…

Subcellular Processes · Quantitative Biology 2016-11-02 Pablo Sartori , Veikko Geyer , Jonathon Howard , Frank Jülicher

Eukaryotic cell motility is crucial during development, wound healing, the immune response, and cancer metastasis. Some eukaryotic cells can swim, but cells more commonly adhere to and crawl along the extracellular matrix. We study the…

Cell Behavior · Quantitative Biology 2019-09-02 Melissa H. Mai , Brian A. Camley