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Recent advances in algorithm-hardware co-design for deep neural networks (DNNs) have demonstrated their potential in automatically designing neural architectures and hardware designs. Nevertheless, it is still a challenging optimization…

Machine Learning · Computer Science 2021-11-29 Hongxiang Fan , Martin Ferianc , Zhiqiang Que , He Li , Shuanglong Liu , Xinyu Niu , Wayne Luk

There exists a significant scale gap between photonic neural network integrated chips and neural networks, which hinders the deployment and application of photonic neural network. Here, we propose hardware-aware lightweight spiking neural…

Special-purpose hardware accelerators are increasingly pivotal for sustaining performance improvements in emerging applications, especially as the benefits of technology scaling continue to diminish. However, designers currently lack…

Programming Languages · Computer Science 2024-04-09 Hongzheng Chen , Niansong Zhang , Shaojie Xiang , Zhichen Zeng , Mengjia Dai , Zhiru Zhang

Machine learning algorithms have made significant advances in many applications. However, their hardware implementation on the state-of-the-art platforms still faces several challenges and are limited by various factors, such as memory…

Neural and Evolutionary Computing · Computer Science 2019-06-24 Xiaocong Du , Gokul Krishnan , Abinash Mohanty , Zheng Li , Gouranga Charan , Yu Cao

Convolutional Neural Networks have dramatically improved in recent years, surpassing human accuracy on certain problems and performance exceeding that of traditional computer vision algorithms. While the compute pattern in itself is…

Computer Vision and Pattern Recognition · Computer Science 2018-07-10 Michaela Blott , Thomas B. Preusser , Nicholas Fraser , Giulio Gambardella , Kenneth OBrien , Yaman Umuroglu , Miriam Leeser

Software-hardware co-design solutions for decimal computation can provide several Pareto points to development of embedded systems in terms of hardware cost and performance. This paper demonstrates how to accurately evaluate such co-design…

Hardware Architecture · Computer Science 2020-03-12 Riaz-ul-haque Mian , Michihiro Shintani , Michiko Inoue

Hardware-firmware co-verification is critical to design trustworthy systems. While formal methods can provide verification guarantees, due to the complexity of firmware and hardware, it can lead to state space explosion. There are promising…

Symbolic Computation · Computer Science 2024-04-18 Aruna Jayasena , Prabhat Mishra

Chase-like decoding algorithms are a popular choice for soft-input decoding of algebraic codes. In this paper, we evaluate the performance of different test pattern sets using three methods. For test pattern sets with a certain structure…

Information Theory · Computer Science 2026-05-12 Tim Janz , Simon Obermüller , Andreas Zunker , Stephan ten Brink

Navigating vast, rugged biological fitness landscapes to discover high-value functional patterns-such as optimal protein sequences-is a central challenge in health informatics. However, conventional algorithms often struggle with the…

Neural and Evolutionary Computing · Computer Science 2025-11-25 Xu Wang , Yiquan Wang , Tin-Yeh Huang , Yuhua Dong , Jia Deng , Longji Xu , Xiang Li , Rui He

Computational protein design is experiencing a transformation driven by AI/ML. However, the range of potential protein sequences and structures is astronomically vast, even for moderately sized proteins. Hence, achieving convergence between…

Distributed, Parallel, and Cluster Computing · Computer Science 2025-10-09 Aymen Alsaadi , Jonathan Ash , Mikhail Titov , Matteo Turilli , Andre Merzky , Shantenu Jha , Sagar Khare

Unlike traditional PCIe-based FPGA accelerators, heterogeneous SoC-FPGA devices provide tighter integrations between software running on CPUs and hardware accelerators. Modern heterogeneous SoC-FPGA platforms support multiple I/O cache…

Hardware Architecture · Computer Science 2019-08-06 Seung Won Min , Sitao Huang , Mohamed El-Hadedy , Jinjun Xiong , Deming Chen , Wen-mei Hwu

In our study, we utilized Intel's Loihi-2 neuromorphic chip to enhance sensor fusion in fields like robotics and autonomous systems, focusing on datasets such as AIODrive, Oxford Radar RobotCar, D-Behavior (D-Set), nuScenes by Motional, and…

Hardware Architecture · Computer Science 2024-08-30 Murat Isik , Karn Tiwari , Muhammed Burak Eryilmaz , I. Can Dikmen

Computational experiments are exploited in finding a well-designed processing path to optimize material structures for desired properties. This requires understanding the interplay between the processing-(micro)structure-property linkages…

Computational Engineering, Finance, and Science · Computer Science 2023-05-04 Junrong Lin , Mahmudul Hasan , Pinar Acar , Jose Blanchet , Vahid Tarokh

Classically, the development of humanoid robots has been sequential and iterative. Such bottom-up design procedures rely heavily on intuition and are often biased by the designer's experience. Exploiting the non-linear coupled design space…

Robotics · Computer Science 2023-01-02 Akhil Sathuluri , Anand Vazhapilli Sureshbabu , Markus Zimmermann

We present A-CODE, a fully atomic unified one-stage protein co-design model that simultaneously refines discrete atom types and continuous atom coordinates. Unlike predominant two-stage methods that cascade structure design with amino…

Quantitative Methods · Quantitative Biology 2026-05-06 Chaoran Cheng , Jiaqi Guan , Milong Ren , Chengyue Gong , Cong Liu , Xinshi Chen , Ge Liu , Wenzhi Xiao

Computational design of protein-binding proteins is a fundamental capability with broad utility in biomedical research and biotechnology. Recent methods have made strides against some target proteins, but on-demand creation of high-affinity…

This work explores the feasibility of specialized hardware implementing the Cortical Learning Algorithm (CLA) in order to fully exploit its inherent advantages. This algorithm, which is inspired in the current understanding of the mammalian…

Emerging Technologies · Computer Science 2024-05-06 Valentin Puente , José Ángel Gregorio

Neurosymbolic AI is an emerging compositional paradigm that fuses neural learning with symbolic reasoning to enhance the transparency, interpretability, and trustworthiness of AI. It also exhibits higher data efficiency making it promising…

Hardware Architecture · Computer Science 2025-03-18 Zishen Wan , Hanchen Yang , Ritik Raj , Che-Kai Liu , Ananda Samajdar , Arijit Raychowdhury , Tushar Krishna

We summarise some of the key statements made at the workshop Form Follows Function at ISC High Performance 2016. The summary highlights what type of co-design the presented projects experience; often in the absence of an explicit co-design…

Mathematical Software · Computer Science 2016-07-12 Tobias Weinzierl

We demonstrate that scalable neuromorphic hardware can implement the finite element method, which is a critical numerical method for engineering and scientific discovery. Our approach maps the sparse interactions between neighboring finite…

Neural and Evolutionary Computing · Computer Science 2025-01-22 Bradley H. Theilman , James B. Aimone