Related papers: Modeling the Complex Dynamics and Changing Correla…
Epilepsy is one of the most prevalent brain disorders that disrupts the lives of millions worldwide. For patients with drug-resistant seizures, there exist implantable devices capable of monitoring neural activity, promptly triggering…
Neural activity patterns related to behavior occur at many scales in time and space from the atomic and molecular to the whole brain. Here we explore the feasibility of interpreting neurophysiological data in the context of many-body…
Epilepsy affects nearly 1% of the global population, of which two thirds can be treated by anti-epileptic drugs and a much lower percentage by surgery. Diagnostic procedures for epilepsy and monitoring are highly specialized and…
Electroencephalogram (EEG) signals are effective tools towards seizure analysis where one of the most important challenges is accurate detection of seizure events and brain regions in which seizure happens or initiates. However, all…
Many coordination phenomena in Nature are grounded on a synchronisation regime. In the case of brain dynamics, such self-organised process allows the neurons of particular brain regions to behave as a whole and thus directly controlling the…
Drug-resistant epilepsy is traditionally characterized by pathologic cortical tissue comprised of seizure-initiating `foci'. These `foci' are thought to be embedded within an epileptic network whose functional architecture dynamically…
Interictal spikes and sharp waves in human EEG are characteristic signatures of epilepsy. These potentials originate as a result of synchronous, pathological discharge of many neurons. The reliable detection of such potentials has been the…
Intracranial EEG (IEEG) is used for 2 main purposes, to determine: (1) if epileptic networks are amenable to focal treatment and (2) where to intervene. Currently these questions are answered qualitatively and sometimes differently across…
Purpose: Understanding fluctuations of seizure severity within individuals is important for defining treatment outcomes and response to therapy, as well as developing novel treatments for epilepsy. Current methods for grading seizure…
Seizure detection from EEG signals is highly challenging due to complex spatiotemporal dynamics and extreme inter-patient variability. To model them, recent methods construct dynamic graphs via statistical correlations, predefined…
Cortical network functioning critically depends on finely tuned interactions to afford neuronal activity propagation over long distances while avoiding runaway excitation. This importance is highlighted by the pathological consequences and…
Pathophysiolpgical modelling of brain systems from microscale to macroscale remains difficult in group comparisons partly because of the infeasibility of modelling the interactions of thousands of neurons at the scales involved. Here, to…
More than 50 million individuals are affected by epilepsy, a chronic neurological disorder characterized by unprovoked, recurring seizures and psychological symptoms. Researchers are working to automatically detect or predict epileptic…
Epilepsy is a dynamic and complex neurological disease affecting about 1% of the worldwide population, among which 30% of the patients are drug-resistant. Epilepsy is characterized by recurrent episodes of paroxysmal neural discharges (the…
Automated epileptic seizure detection from electroencephalogram (EEG) remains challenging due to significant individual differences in EEG patterns across patients. While existing studies achieve high accuracy with patient-specific…
Seizure activity is a ubiquitous and pernicious pathophysiology that, in principle, should yield to mathematical treatments of (neuronal) ensemble dynamics - and therefore interventions on stochastic chaos. A seizure can be characterised as…
Epilepsy is a chronic neurological disorder affecting more than 65 million people worldwide and manifested by recurrent unprovoked seizures. The unpredictability of seizures not only degrades the quality of life of the patients, but it can…
Predicting post-operative seizure freedom using functional correlation networks derived from interictal intracranial EEG has shown some success. However, there are important challenges to consider. 1: electrodes physically closer to each…
Neural mass models are used to simulate cortical dynamics and to explain the electrical and magnetic fields measured using electro- and magnetoencephalography. Simulations evince a complex phase-space structure for these kinds of models;…
Diagnosing epilepsy requires accurate seizure detection and classification, but traditional manual EEG signal analysis is resource-intensive. Meanwhile, automated algorithms often overlook EEG's geometric and semantic properties critical…