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Related papers: Finite size effects in non-equilibrium membrane ph…

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Cell membranes are out of thermodynamic equilibrium notably because of membrane recycling, i.e. active exchange of material with the cytosol. We propose an analytically tractable model of biomembrane predicting the effects of recycling on…

Soft Condensed Matter · Physics 2016-04-18 Mareike Berger , Manoel Manghi , Nicolas Destainville

Non-equilibrium cluster-cluster aggregation of particles diffusing in or at the cell membrane has been hypothesized to lead to domains of finite size in different biological contexts such as lipid rafts, cell adhesion complexes, or…

Soft Condensed Matter · Physics 2023-08-30 Renaud Baillou , Jonas Ranft

In many cellular signaling pathways, key components form clusters at the cell membrane. Although much work has focused on the mechanisms behind such cluster formation, the implications for downstream signaling remain poorly understood.…

Molecular Networks · Quantitative Biology 2012-03-14 Andrew Mugler , Aimee Gotway Bailey , Koichi Takahashi , Pieter Rein ten Wolde

The equilibrium size distribution function of clusters (nanoparticles) in the system of finite number of molecules (atoms) in finite closed volume with constant total energy (isolated system) is found using methods of statistical…

Statistical Mechanics · Physics 2013-06-04 I. H. Umirzakov

We propose a model that leads to the formation of non-equilibrium finite-size domains in a biological membrane. Our model considers the active conformational change of the inclusions and the coupling between inclusion density and membrane…

Soft Condensed Matter · Physics 2007-05-23 Chien-Hsun Chen

We discuss the implications of finite size effects on the determination of the order of a phase transition which may occur in infinite systems. We introduce a specific model to which we apply different tests. They are aimed to characterise…

Nuclear Theory · Physics 2009-10-31 J. M. Carmona , N. Michel , J. Richert , P. Wagner

We study the coarsening of strongly microphase separated membrane domains in the presence of recycling of material. We study the dynamics of the domain size distribution under both scale-free and size-dependent recycling. Closed form…

Subcellular Processes · Quantitative Biology 2018-05-11 S. Alex Rautu , G. Rowlands , M. S. Turner

The thermodynamical cluster model is known to present a first-order liquid-gas phase transition in the idealized case of an uncharged, infinitely extended medium. However, in most practical applications of this model, the system is finite…

Nuclear Theory · Physics 2016-04-13 S. Mallik , F. Gulminelli , G. Chaudhuri

It has recently been proposed that proteins embedded in lipidic bio-membranes can spontaneously self-organize into stable small clusters, or membrane nano-domains, due to the competition between short-range attractive and longer-range…

Soft Condensed Matter · Physics 2011-06-08 Nicolas Meilhac , Nicolas Destainville

A physical scenario accounting for the existence of size-limited submicrometric domains in cell membranes is proposed. It is based on the numerical investigation of the counterpart, in lipidic membranes where proteins are diffusing, of the…

Soft Condensed Matter · Physics 2015-06-25 Nicolas Destainville

We propose a model to explain finite-size effects in intracellular microrheology observed in experiments. The constrained dynamics of the particles in the intracellular medium, treated as a viscoelastic medium, is described by means of a…

Soft Condensed Matter · Physics 2009-11-11 I. Santamaria-Holek , J. M. Rubi

A finite size scaling theory, originally developed only for transitions to absorbing states [Phys. Rev. E {\bf 92}, 062126 (2015)], is extended to distinct sorts of discontinuous nonequilibrium phase transitions. Expressions for quantities…

Statistical Mechanics · Physics 2018-06-13 Marcelo M. de Oliveira , M. G. E. da Luz , Carlos E. Fiore

The long-time behaviour of spin-spin correlators in the slow relaxation of systems undergoing phase-ordering kinetics is studied in geometries of finite size. A phenomenological finite-size scaling ansatz is formulated and tested through…

Statistical Mechanics · Physics 2023-03-06 Malte Henkel

Cell size is a fundamental determinant of cellular physiology, influencing processes such as growth, division, and function. In this study, we develop a segmented mathematical framework to investigate how different control mechanisms…

Cell Behavior · Quantitative Biology 2026-02-02 Shuqi Fan , Yuhang Zhang , Jinzhi Lei

It is common knowledge that the microcanonical, canonical, and grand-canonical ensembles are equivalent in thermodynamically large systems. Here, we study finite-size effects in the latter two ensembles. We show that contrary to naive…

Statistical Mechanics · Physics 2017-09-04 Deepak Iyer , Mark Srednicki , Marcos Rigol

We study theoretically in the present work the self-assembly of molecules in an open system, which is fed by monomers and depleted in partial or complete clusters. Such a scenario is likely to occur for example in the context of viral…

Biological Physics · Physics 2014-02-18 Martin Castelnovo , Timothée Verdier , Lionel Foret

We perform molecular dynamics simulations in order to examine the rheological transition of fluids confined in a small space. By performing finite-size scaling analysis, we demonstrate that this rheological transition results from the…

Statistical Mechanics · Physics 2009-11-11 Michio Otsuki

Groups of cells, including clusters of cancerous cells, multicellular organisms, and developing organs, may both grow and break apart. What physical factors control these fractures? In these processes, what sets the eventual size of…

Biological Physics · Physics 2026-04-03 Wei Wang , Brian A. Camley

Spatial heterogeneity is a hallmark of living systems, even at the molecular scale in individual cells. A key example is the partitioning of membrane-bound proteins via lipid domain formation or cytoskeleton-induced corralling. Yet the…

Molecular Networks · Quantitative Biology 2013-11-19 Andrew Mugler , Filipe Tostevin , Pieter Rein ten Wolde

Biomolecular condensates in cells are often rich in catalytically-active enzymes. This is particularly true in the case of the large enzymatic complexes known as metabolons, which contain different enzymes that participate in the same…

Subcellular Processes · Quantitative Biology 2021-10-20 Vincent Ouazan-Reboul , Jaime Agudo-Canalejo , Ramin Golestanian
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