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Deep, high-resolution imaging is essential for unraveling biological complexity and advancing medical diagnostics, yet scattering fundamentally limits optical methods. Among the most promising approaches, photoacoustic imaging achieves…

Pulsatile flow through compressed or defective blood vessels is a topic of fundamental importance in hemodynamics, particularly in cardiovascular research. This study examines flow dynamics within a tube with a bipolar cross section,…

Medical Physics · Physics 2025-03-04 Doyeol , Ahn

Noise plays a crucial role in the regulation of cellular and organismal function and behavior. Exploring noise's impact is key to understanding fundamental biological processes, such as gene expression, signal transduction, and the…

Molecular Networks · Quantitative Biology 2025-12-16 Chuanbo Liu , Yu Fu , Lu Lin , Elliot L. Elson , Jin Wang

Physics-Informed Neural Networks (PINNs) show significant potential for solving inverse problems, especially when observations are limited and sparse, provided that the relevant physical equations are known. We use PINNs to estimate smooth…

Numerical Analysis · Mathematics 2025-08-06 Moises Sierpe , Ernesto Castillo , Hernan Mella , Felipe Galarce

Major biological discoveries have been made by interrogating living organisms with light. However, the limited penetration of unscattered photons within biological tissues severely limits the depth range covered by optical methods.…

We propose a method for accurately detecting bioacoustic sound events that is robust to overlapping events, a common issue in domains such as ethology, ecology and conservation. While standard methods employ a frame-based, multi-label…

We use synchronous movies from the Dutch Open Telescope sampling the G band, Ca II and Halpha with five-wavelength profile sampling to study the response of the chromosphere to acoustic events in the underlying photosphere. We first compare…

Astrophysics · Physics 2009-11-13 Robert J. Rutten , Bob van Veelen , Peter Suetterlin

Various biological processes such as transport of oxygen and nutrients, thrombus formation, vascular angiogenesis and remodeling are related to cellular/subcellular level biological processes, where mesoscopic simulations resolving detailed…

The time course of oxidative damage in different brain regions was investigated in the gerbil model of transient cerebral ischemia. Animals were subjected to both common carotid arteries occlusion for 5 min. After the end of ischemia and at…

Tissues and Organs · Quantitative Biology 2007-08-06 E. Candelario-Jalil , N. H. Mhadu , S. M. Al-Dalain , G. Martinez , O. S. Leon

One of the main applications of photoacoustic (PA) imaging is the recovery of functional tissue properties, such as blood oxygenation (sO2). This is typically achieved by linear spectral unmixing of relevant chromophores from multispectral…

Medical Physics · Physics 2022-04-19 Janek Gröhl , Thomas Kirchner , Tim Adler , Lena Maier-Hein

Several centimeters below the skin lie multiple biomarkers, such as glucose, oxygenation, and blood flow. Monitoring these biomarkers regularly and in a non-invasive manner would enable early insight into metabolic status and vascular…

Medical Physics · Physics 2025-10-30 Talia Xu , Caitlin Smith , Charles Lo , Jami Shepherd , Gijs van Soest , Marco Zuniga

Research in bioacoustics, neuroscience, and linguistics often uses birdsong as a proxy to acquire knowledge across diverse areas. This requires audio models to annotate and parse the birdsong. Developing such models requires precise,…

Machine Learning · Computer Science 2026-05-20 Houtan Ghaffari , Lukas Rauch , Paul Devos

Multi-spectral optoacoustic tomography (MSOT) is an emerging optical imaging method providing multiplex molecular and functional information from the rodent brain. It can be greatly augmented by magnetic resonance imaging (MRI) that offers…

Image and Video Processing · Electrical Eng. & Systems 2021-09-07 Yexing Hu , Berkan Lafci , Artur Luzgin , Hao Wang , Jan Klohs , Xose Luis Dean-Ben , Ruiqing Ni , Daniel Razansky , Wuwei Ren

We propose a new method of optical lattice modulation spectroscopy for studying the spectral function of ultracold bosons in an optical lattice. We show that different features of the single particle spectral function in different quantum…

Quantum Gases · Physics 2015-03-18 Rajdeep Sensarma , K. Sengupta , S. Das Sarma

Identification of bird species from audio records is one of the challenging tasks due to the existence of multiple species in the same recording, noise in the background, and long-term recording. Besides, choosing a proper acoustic feature…

Sound · Computer Science 2022-01-04 Nahian Ibn Hasan

Intraoperative optical imaging is a localization technique for the functional areas of the human brain cortex during neurosurgical procedures. These areas can be assessed by monitoring cerebral hemodynamics and metabolism. A robust…

Chronic Obstructive Pulmonary Disease (COPD) is a chronic lung condition characterized by airflow obstruction. Current diagnostic methods primarily rely on identifying prominent features in spirometry (Volume-Flow time series) to detect…

Machine Learning · Computer Science 2025-03-04 Shuhao Mei , Xin Li , Yuxi Zhou , Jiahao Xu , Yong Zhang , Yuxuan Wan , Shan Cao , Qinghao Zhao , Shijia Geng , Junqing Xie , Shengyong Chen , Shenda Hong

A pulse oximeter is an optical device that monitors tissue oxygenation levels. Traditionally, these devices estimate the oxygenation level by measuring the intensity of the transmitted light through the tissue and are embedded into everyday…

Certain species of living creatures are known to orientate themselves in the geomagnetic field. Given the small magnitude of approximately 48 {\mu}T, the underlying quantum mechanical phenomena are expected to exhibit coherence times…

Multispectral imaging (MSI) can provide information about tissue oxygenation, perfusion and potentially function during surgery. In this paper we present a novel, near real-time technique for intrinsic measurements of total haemoglobin…

Computer Vision and Pattern Recognition · Computer Science 2017-06-23 Geoffrey Jones , Neil T. Clancy , Yusuf Helo , Simon Arridge , Daniel S. Elson , Danail Stoyanov
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