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Objective: To (1) demonstrate the implementation of a data science platform built on open-source technology within a large, academic healthcare system and (2) describe two computational healthcare applications built on such a platform.…

Online scientific publications provide vast opportunities for researchers. Alas, the quantity and the rate of increase in the articles make the utilization of these resources very challenging. This work presents as inquiry-based approach to…

Information Retrieval · Computer Science 2020-01-03 S. Uskudarli , E. Gökdeniz , R. Canbeyli

Novel compute systems are an emerging research topic, aiming towards building next-generation compute platforms. For these systems to thrive, they need to be provided as research infrastructure to allow acceptance and usage by a large…

Hardware Architecture · Computer Science 2025-09-24 Yannik Stradmann , Joscha Ilmberger , Eric Müller , Johannes Schemmel

This article presents our steps to integrate complex and partly unstructured medical data into a clinical research database with subsequent decision support. Our main application is an integrated faceted search tool, accompanied by the…

Human-Computer Interaction · Computer Science 2018-10-31 Daniel Sonntag , Hans-Jürgen Profitlich

Neuroimaging has profoundly enhanced our understanding of the human brain by characterizing its structure, function, and connectivity through modalities like MRI, fMRI, EEG, and PET. These technologies have enabled major breakthroughs…

Applications · Statistics 2026-02-16 Jian Kang , Thomas Nichols , Lexin Li , Martin A. Lindquist , Hongtu Zhu

Understanding neural activity and information representation is crucial for advancing knowledge of brain function and cognition. Neural activity, measured through techniques like electrophysiology and neuroimaging, reflects various aspects…

Neurons and Cognition · Quantitative Biology 2024-07-22 Fengyu Yang , Chao Feng , Daniel Wang , Tianye Wang , Ziyao Zeng , Zhiyang Xu , Hyoungseob Park , Pengliang Ji , Hanbin Zhao , Yuanning Li , Alex Wong

The connection between the design and delivery of health care services using information technology is known as health informatics. It involves data usage, validation, and transfer of an integrated medical analysis using neural networks of…

Quantitative Methods · Quantitative Biology 2022-08-08 Amin Gasmi

Computational biomechanics of the brain for neurosurgery is an emerging area of research recently gaining in importance and practical applications. This review paper presents the contributions of the Intelligent Systems for Medicine…

Computational Engineering, Finance, and Science · Computer Science 2019-04-03 K. Miller , G. R. Joldes , G. Bourantas , S. K. Warfield , D. E. Hyde , R. Kikinis , A. Wittek

Hybrid modeling combining data-driven techniques and numerical methods is an emerging and promising research direction for efficient climate simulation. However, previous works lack practical platforms, making developing hybrid modeling a…

Atmospheric and Oceanic Physics · Physics 2022-09-20 Xin Wang , Wei Xue , Yilun Han , Guangwen Yang

Medical data mainly includes various types of biomedical signals and medical images, which can be used by professional doctors to make judgments on patients' health conditions. However, the interpretation of medical data requires a lot of…

Neural and Evolutionary Computing · Computer Science 2023-08-15 X. Li , X. Zhang , X. Yi , D. Liu , H. Wang , B. Zhang , B. Zhang , D. Zhao , L. Wang

Data-intensive scientific workflows increasingly rely on high-performance computing (HPC) systems, complementing traditional Grid and Cloud platforms. However, workflow scheduling on HPC infrastructures remains challenging due to the…

Distributed, Parallel, and Cluster Computing · Computer Science 2025-11-26 Aurelio Vivas , Harold Castro

Deep Learning has revolutionized various fields, including Computer Vision, Natural Language Processing, as well as Biomedical research. Within the field of neuroscience, specifically in electrophysiological neuroimaging, researchers are…

Machine Learning · Computer Science 2022-04-14 Dung Truong , Manisha Sinha , Kannan Umadevi Venkataraju , Michael Milham , Arnaud Delorme

We present Clinica (www.clinica.run), an open-source software platform designed to make clinical neuroscience studies easier and more reproducible. Clinica aims for researchers to i) spend less time on data management and processing, ii)…

Neurophysiology research has demonstrated that it is possible and valuable to investigate sensory processing in scenarios involving continuous sensory streams, such as speech and music. Over the past 10 years or so, novel analytic…

Localizing neuronal activity in the brain, both in time and in space, is a central challenge to advance the understanding of brain function. Because of the inability of any single neuroimaging techniques to cover all aspects at once, there…

Neurons and Cognition · Quantitative Biology 2013-07-09 Yaroslav O. Halchenko , Michael Hanke , James V. Haxby , Stephen Jose Hanson , Christoph S. Herrmann

The rapid advancement in neurotechnology in recent years has created an emerging critical intersection between neurotechnology and security. Implantable devices, non-invasive monitoring, and non-invasive therapies all carry with them the…

Cryptography and Security · Computer Science 2025-01-28 Bryce Allen Bagley , Claudia K Petritsch

Deep learning has been recently used for the analysis of neuroimages, such as structural magnetic resonance imaging (MRI), functional MRI, and positron emission tomography (PET), and has achieved significant performance improvements over…

Image and Video Processing · Electrical Eng. & Systems 2020-05-12 Li Zhang , Mingliang Wang , Mingxia Liu , Daoqiang Zhang

Investigation of the neural basis of self-generated thought is moving beyond a simple identification with default network activation toward a more comprehensive view recognizing the role of the frontoparietal control network and other…

Neurons and Cognition · Quantitative Biology 2016-07-06 Kieran C. R. Fox , Jessica R. Andrews-Hanna , Kalina Christoff

Nuclear Magnetic Resonance (NMR) spectroscopy has served as a powerful analytical tool for studying molecular structure and dynamics in chemistry and biology. However, the processing of raw data acquired from NMR spectrometers and…

Quantitative Methods · Quantitative Biology 2023-09-15 Di Guo , Sijin Li , Jun Liu , Zhangren Tu , Tianyu Qiu , Jingjing Xu , Liubin Feng , Donghai Lin , Qing Hong , Meijin Lin , Yanqin Lin , Xiaobo Qu

Data sharing efforts increasingly contribute to the acceleration of scientific discovery. Neuroimaging data is accumulating in distributed domain-specific databases and there is currently no integrated access mechanism nor an accepted…