Related papers: Important Molecular Descriptors Selection Using Se…

Liquid chromatography with tandem mass spectrometry (LC-MS/MS) based proteomics is a well-established research field with major applications such as identification of disease biomarkers, drug discovery, drug design and development. In…

The propensity score (PS) is often used to control for large numbers of covariates in high-dimensional healthcare database studies. The least absolute shrinkage and selection operator (LASSO) has become the most widely used tool for fitting…

Inference-time compute has re-emerged as a practical way to improve LLM reasoning. Most test-time scaling (TTS) algorithms rely on autoregressive decoding, which is ill-suited to discrete diffusion language models (dLLMs) due to their…

In the era of information explosion, efficiently leveraging large-scale unlabeled data while minimizing the reliance on high-quality pixel-level annotations remains a critical challenge in the field of medical imaging. Semi-supervised…

Feature selection is the process of identifying statistically most relevant features to improve the predictive capabilities of the classifiers. To find the best features subsets, the population based approaches like Particle Swarm…

Self-supervised learning offers an efficient way of extracting rich representations from various types of unlabeled data while avoiding the cost of annotating large-scale datasets. This is achievable by designing a pretext task to form…

Large language models (LLMs) have shown remarkable capability in numerous tasks and applications. However, fine-tuning LLMs using high-quality datasets under external supervision remains prohibitively expensive. In response, LLM…

Speculative decoding accelerates inference in large language models (LLMs) by generating draft tokens for target model verification. Current approaches for obtaining draft tokens rely on lightweight draft models or additional model…

We present a new procedure for enhanced variable selection for component-wise gradient boosting. Statistical boosting is a computational approach that emerged from machine learning, which allows to fit regression models in the presence of…

The aim of this work is to propose an ensemble of descriptors for Melanoma Classification, whose performance has been evaluated on validation and test datasets of the melanoma challenge 2018. The system proposed here achieves a strong…

Semantic Textual Similarity (STS) is a crucial component of many Natural Language Processing (NLP) applications. However, existing approaches typically reduce semantic nuances to a single score, limiting interpretability. To address this,…

Apart from the high accuracy of machine learning models, what interests many researchers in real-life problems (e.g., fraud detection, credit scoring) is to find hidden patterns in data; particularly when dealing with their challenging…

Accurate sample classification using transcriptomics data is crucial for advancing personalized medicine. Achieving this goal necessitates determining a suitable sample size that ensures adequate statistical power without undue resource…

Pretraining large language models (LLMs) on vast and heterogeneous datasets is crucial for achieving state-of-the-art performance across diverse downstream tasks. However, current training paradigms treat all samples equally, overlooking…

Spectroscopic properties of molecules holds great importance for the description of the molecular response under the effect of an UV/Vis electromagnetic radiation. Computationally expensive ab initio (e.g. MultiConfigurational SCF, Coupled…

Screening methods are useful tools for variable selection in regression analysis when the number of predictors is much larger than the sample size. Factor analysis is used to eliminate multicollinearity among predictors, which improves the…

Background: High-throughput proteomics techniques, such as mass spectrometry (MS)-based approaches, produce very high-dimensional data-sets. In a clinical setting one is often interested in how mass spectra differ between patients of…

Supervised Fine-Tuning (SFT) of the language backbone plays a pivotal role in adapting Vision-Language Models (VLMs) to specialized domains such as medical reasoning. However, existing SFT practices often rely on unfiltered textual datasets…

Sparse model estimation is a topic of high importance in modern data analysis due to the increasing availability of data sets with a large number of variables. Another common problem in applied statistics is the presence of outliers in the…

In this study, we propose Shortcut Fine-Tuning (SFT), a new approach for addressing the challenge of fast sampling of pretrained Denoising Diffusion Probabilistic Models (DDPMs). SFT advocates for the fine-tuning of DDPM samplers through…