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We prove weak convergence in a separable Hilbert space for estimators of high-dimensional regression coefficients, which yields asymptotic normality and enables direct use of standard asymptotic tools such as the continuous mapping theorem.…

Statistics Theory · Mathematics 2026-05-05 Kou Fujimori , Koji Tsukuda

We consider multivariate two-sample tests of means, where the location shift between the two populations is expected to be related to a known graph structure. An important application of such tests is the detection of differentially…

Quantitative Methods · Quantitative Biology 2014-05-16 Laurent Jacob , Pierre Neuvial , Sandrine Dudoit

Estimation and hypothesis tests for the covariance matrix in high dimensions is a challenging problem as the traditional multivariate asymptotic theory is no longer valid. When the dimension is larger than or increasing with the sample…

Methodology · Statistics 2020-11-18 Deepak Nag Ayyala , Santu Ghosh , Daniel F. Linder

Recently a distribution free approach for testing parametric hypotheses based on unitary transformations has been suggested in \cite{Khm13, Khm16, Khm17} and further studied in \cite{Ngu17} and \cite{Rob19}. In this note we show that the…

Methodology · Statistics 2020-02-10 Estate V. Khmaladze

This paper looks at effects, due to the boundary, on inference in logistic regression. It shows that first -- and, indeed, higher -- order asymptotic results are not uniform across the model. Near the boundary, effects such as high…

Methodology · Statistics 2013-04-08 Karim Anaya-Izquierdo , Frank Critchley , Paul Marriott

For a particular disease there may be two diagnostic tests developed, where each of the tests is subject to several studies. A quadrivariate generalized linear mixed model (GLMM) has been recently proposed to joint meta-analyse and compare…

Methodology · Statistics 2019-12-03 Aristidis K. Nikoloulopoulos

We provide an upper bound as a random variable for the functions of estimators in high dimensions. This upper bound may help establish the rate of convergence of functions in high dimensions. The upper bound random variable may converge…

Econometrics · Economics 2020-08-07 Mehmet Caner , Xu Han

In this article, we develop a distributed variable screening method for generalized linear models. This method is designed to handle situations where both the sample size and the number of covariates are large. Specifically, the proposed…

Methodology · Statistics 2024-05-09 Tianbo Diao , Lianqiang Qu , Bo Li , Liuquan Sun

Likelihood ratio tests are widely used to test statistical hypotheses about parametric families of probability distributions. If interest is restricted to a subfamily of distributions, then it is natural to inquire if the restricted LRT is…

Statistics Theory · Mathematics 2016-08-02 Michael W. Trosset , Mingyue Gao , Carey E. Priebe

Multi-collinearity is a wide-spread phenomenon in modern statistical applications and when ignored, can negatively impact model selection and statistical inference. Classic tools and measures that were developed for "$n>p$" data are not…

Methodology · Statistics 2022-03-22 Wei Q. Deng , Radu V. Craiu , Lei Sun

Diagnostic test accuracy studies typically report the number of true positives, false positives, true negatives and false negatives. There usually exists a negative association between the number of true positives and true negatives,…

Methodology · Statistics 2015-11-06 Aristidis K. Nikoloulopoulos

De-biased lasso has emerged as a popular tool to draw statistical inference for high-dimensional regression models. However, simulations indicate that for generalized linear models (GLMs), de-biased lasso inadequately removes biases and…

Methodology · Statistics 2020-06-24 Lu Xia , Bin Nan , Yi Li

We introduce a new method for two-sample testing of high-dimensional linear regression coefficients without assuming that those coefficients are individually estimable. The procedure works by first projecting the matrices of covariates and…

Statistics Theory · Mathematics 2023-05-11 Fengnan Gao , Tengyao Wang

We consider the joint inference of regression coefficients and the inverse covariance matrix for covariates in high-dimensional probit regression, where the predictors are both relevant to the binary response and functionally related to one…

Methodology · Statistics 2022-03-15 Xuan Cao , Kyoungjae Lee

We consider linear regression in the high-dimensional regime where the number of observations $n$ is smaller than the number of parameters $p$. A very successful approach in this setting uses $\ell_1$-penalized least squares (a.k.a. the…

Methodology · Statistics 2014-02-05 Adel Javanmard , Andrea Montanari

In the genomic era, the identification of gene signatures associated with disease is of significant interest. Such signatures are often used to predict clinical outcomes in new patients and aid clinical decision-making. However, recent…

Methodology · Statistics 2019-03-27 Naim U. Rashid , Quefeng Li , Jen Jen Yeh , Joseph G. Ibrahim

Tests for proportional hazards assumption concerning specified covariates or groups of covariates are proposed. The class of alternatives is wide: log-hazard rates under different values of covariates may cross, approach, go away. The data…

Statistics Theory · Mathematics 2020-01-20 Vilijandas Bagdonavičius , Rūta Levulienė

We consider the problem of testing the mean of high-dimensional data when the dimension may grow without explicit rate restrictions relative to the sample size. The proposed procedure is based on the statistic V_n = n||Xn||^2, which avoids…

Statistics Theory · Mathematics 2026-05-18 Dietmar Ferger

Let $(Y,(X_i)_{i\in\mathcal{I}})$ be a zero mean Gaussian vector and $V$ be a subset of $\mathcal{I}$. Suppose we are given $n$ i.i.d. replications of the vector $(Y,X)$. We propose a new test for testing that $Y$ is independent of…

Statistics Theory · Mathematics 2008-05-23 Nicolas Verzelen , Fanny Villers

Consider the problem of estimating the local average treatment effect with an instrument variable, where the instrument unconfoundedness holds after adjusting for a set of measured covariates. Several unknown functions of the covariates…

Methodology · Statistics 2020-09-22 Baoluo Sun , Zhiqiang Tan