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Synthesizing missing modalities in multi-modal magnetic resonance imaging (MRI) is vital for ensuring diagnostic completeness, particularly when full acquisitions are infeasible due to time constraints, motion artifacts, and patient…

Computer Vision and Pattern Recognition · Computer Science 2026-02-24 Yue Zhang , Zhizheng Zhuo , Siyao Xu , Shan Lv , Zhaoxi Liu , Jun Qiu , Qiuli Wang , Yaou Liu , S. Kevin Zhou

Current treatment planning of patients diagnosed with a brain tumor, such as glioma, could significantly benefit by accessing the spatial distribution of tumor cell concentration. Existing diagnostic modalities, e.g. magnetic resonance…

X-ray CT dose measurement has mainly been performed using an ionization chamber dosimeter. Therefore, the dose distribution has not been sufficiently studied. We investigated the importance of evaluating the two or three-dimensional dose…

Multimodal imaging analysis often relies on joint latent representations, yet these approaches rarely define what information is shared versus modality-specific. Clarifying this distinction is clinically relevant, as it delineates the…

Computer Vision and Pattern Recognition · Computer Science 2026-04-09 Sonja Adomeit , Kartikay Tehlan , Lukas Förner , Katharina Weisser , Helen Scholtiseek , David Kaufmann , Julie Steinestel , Constantin Lapa , Thomas Kröncke , Thomas Wendler

Photoacoustic (PA) waves are strongly distorted and attenuated in skull bone. To study these effects on PA imaging, we designed and 3D-printed tissue-mimicking phantoms of human skull. We present a comparison of results in phantom and ex…

Medical Physics · Physics 2025-02-18 Hannah Linde , Saskia Menzer , Jan Laufer , Thomas Kirchner

Determining the brain perfusion is an important task for the diagnosis and treatment of vascular diseases such as occlusions and intracerebral haemorrhage. Even after successful diagnosis and treatment, there is a high risk of restenosis or…

Purpose: To validate the accuracy of 4D Monte Carlo (4DMC) simulations to calculate dose deliveries to a deforming anatomy in the presence of realistic respiratory motion traces. A previously developed deformable lung phantom comprising an…

Medical Physics · Physics 2023-05-04 Sara Gholampourkashi , Joanna E. Cygler , Bernie Lavigne , Emily Heath

Prostate cancer is the most common disease in men and the second leading cause of death from cancer. Generic large imaging instruments used in cancer diagnosis have sensitivity, spatial resolution, and contrast inadequate for the task of…

Purpose: To evaluate reliability of upright CT for proton dose calculation and feasibility of a simplified phantom configuration for accelerated routine QA. Methods: A calibration phantom was scanned on an upright CT following consensus…

We developed a new magnetic resonance imaging method called multinuclear fingerprinting (MNF) which leverages simultaneously-acquired proton (1H) and sodium (23Na) data to generate seven quantitative maps of the whole brain: proton density…

Medical Physics · Physics 2026-05-25 Gonzalo G. Rodriguez , Zidan Yu , Lauren O'Donnell , Martijn A. Cloos , Guillaume Madelin

Space radiation remains one of the primary hazards to spaceflight crews. The unique nature of the intravehicular radiation spectrum makes prediction of biological outcomes difficult, with computational simulation-based efforts stymied by…

Medical Physics · Physics 2023-08-24 Chesal MA , Blue RS , Aunon-Chancellor SA , Chancellor JC

Ultra high field (UHF) brain MRI has proved its value by providing enhanced SNR, contrast, and higher resolution derived from the higher magnetic field (B0). Nonetheless, with the increased B0 of UHF MRI, the transmit RF magnetic field…

Medical Physics · Physics 2019-11-14 Yunchan Hwang , Hansol Noh , Minkyu Park , Jongho Lee , Namkyoo Park

Magnetic continuum robots (MCRs) enable minimally invasive navigation through tortuous anatomical channels, yet axially magnetized designs have largely been limited to bending-only motion. To expand deformation capabilities, this paper…

Robotics · Computer Science 2025-10-03 Wendu Zhang , Heng Wang , Shuangyi Wang , Yuanrui Huang

Background: Treatment verification with PET imaging in charged particle therapy is conventionally done by comparing measurements of spatial distributions with Monte Carlo (MC) predictions. However, decay curves can provide additional…

Multimodal magnetic resonance imaging (MRI) provides complementary information for sub-region analysis of brain tumors. Plenty of methods have been proposed for automatic brain tumor segmentation using four common MRI modalities and…

Image and Video Processing · Electrical Eng. & Systems 2023-03-10 Hong Liu , Dong Wei , Donghuan Lu , Jinghan Sun , Liansheng Wang , Yefeng Zheng

Detecting anomalies in brain MRI scans using supervised deep learning methods presents challenges due to anatomical diversity and labor-intensive requirement of pixel-level annotations. Generative models like Denoising Diffusion…

Image and Video Processing · Electrical Eng. & Systems 2024-10-01 Vivek Kumar Trivedi , Bheeshm Sharma , P. Balamurugan

Multi-modal neuroimaging analysis is crucial for a comprehensive understanding of brain function and pathology, as it allows for the integration of different imaging techniques, thus overcoming the limitations of individual modalities.…

Computer Vision and Pattern Recognition · Computer Science 2025-03-27 Weiheng Yao , Zhihan Lyu , Mufti Mahmud , Ning Zhong , Baiying Lei , Shuqiang Wang

According to the 2021 World Health Organization (WHO) Classification scheme for gliomas, glioma segmentation is a very important basis for diagnosis and genotype prediction. In general, 3D multimodal brain MRI is an effective diagnostic…

Image and Video Processing · Electrical Eng. & Systems 2025-06-23 Xiaoyu Shi , Shurong Chai , Yinhao Li , Jingliang Cheng , Jie Bai , Guohua Zhao , Yen-Wei Chen

Brain tumor represents one of the most fatal cancers around the world, and is very common in children and the elderly. Accurate identification of the type and grade of tumor in the early stages plays an important role in choosing a precise…

Computer Vision and Pattern Recognition · Computer Science 2024-01-18 Dunyuan Xu , Xi Wang , Jinyue Cai , Pheng-Ann Heng
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