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Models of strategy evolution on static networks help us understand how population structure can promote the spread of traits like cooperation. One key mechanism is the formation of altruistic spatial clusters, where neighbors of a…

Physics and Society · Physics 2023-09-07 Qi Su , Alex McAvoy , Joshua B. Plotkin

Coexistence of individuals with different species or phenotypes is often found in nature in spite of competition between them. Stable coexistence of multiple types of individuals have implications for maintenance of ecological biodiversity…

Disordered Systems and Neural Networks · Physics 2007-05-23 Naoki Masuda , Norio Konno

We introduce and analyze several aspects of a new model for cell differentiation. It assumes that differentiation of progenitor cells is a continuous process. From the mathematical point of view, it is based on partial differential…

Analysis of PDEs · Mathematics 2013-01-21 Marie Doumic , Anna Marciniak-Czochra , Benoit Perthame , Jorge P. Zubelli

The motility of eukaryotic cells is strongly influenced by their environment, with confined cells often developing qualitatively different motility patterns from those migrating on simple two-dimensional substrates. Recent experiments,…

Cell Behavior · Quantitative Biology 2024-12-24 Pedrom Zadeh , Brian A. Camley

Bacterial conglomerates such as biofilms and microcolonies are ubiquitous in nature and play an important role in industry and medicine. In contrast to well-mixed, diluted cultures routinely used in microbial research, bacteria in a…

Biological Physics · Physics 2017-01-13 Fred F. Farrell , Matti Gralka , Oskar Hallatschek , Bartlomiej Waclaw

The internal energy associated with the defect microstructure of strongly deformed crystals provides an important driving force for grain boundary motion during recrystallization. Typical dislocation microstructures are strongly…

Materials Science · Physics 2026-01-13 Yufan Zhang , Michael Zaiser

Diffusive transport is a universal phenomenon, throughout both biological and physical sciences, and models of diffusion are routinely used to interrogate diffusion-driven processes. However, most models neglect to take into account the…

Quantitative Methods · Quantitative Biology 2015-10-28 Paul R. Taylor , Christian A. Yates , Matthew J. Simpson , Ruth E. Baker

We introduce an evolutionary metacommunity of multitrophic food webs on several habitats coupled by migration. In contrast to previous studies that focus either on evolutionary or on spatial aspects, we include both and investigate the…

Populations and Evolution · Quantitative Biology 2018-04-20 Korinna T. Allhoff , Eva Marie Weiel , Tobias Rogge , Barbara Drossel

The ubiquitous existence of microbial communities marks the importance of understanding how species interact within the community to coexist and their spatial organization. We study a two-species mutualistic cross-feeding model through a…

Populations and Evolution · Quantitative Biology 2022-10-31 Jiaqi. Lin , Hui. Sun , JiaJia Dong

The function of biomolecules such as proteins depends on their ability to interconvert between a wide range of structures or "conformations." Researchers have endeavored for decades to develop computational methods to predict the…

Biomolecules · Quantitative Biology 2026-02-05 Daniel D. Richman , Jessica Karaguesian , Carl-Mikael Suomivuori , Ron O. Dror

We study the effect of migration between coupled populations, or patches, on the stability properties of multistrain disease dynamics. The epidemic model used in this work displays a Hopf bifurcation to oscillations in a single well mixed…

Populations and Evolution · Quantitative Biology 2009-07-29 Simone Bianco , Leah B. Shaw

Cells and organisms follow aligned structures in their environment, a process that can generate persistent migration paths. Kinetic transport equations are a popular modelling tool for describing biological movements at the mesoscopic…

Cell Behavior · Quantitative Biology 2021-01-13 Nadia Loy , Thomas Hillen , Kevin John Painter

In multicellular organisms, several cell states coexist. For determining each cell type, cell-cell interactions are often essential, in addition to intracellular gene expression dynamics. Based on dynamical systems theory, we propose a…

Cell Behavior · Quantitative Biology 2007-12-05 Akihiko Nakajima , Kunihiko Kaneko

Collections of cells exhibit coherent migration during morphogenesis, cancer metastasis, and wound healing. In many cases, bigger clusters split, smaller sub-clusters collide and reassemble, and gaps continually emerge. The connections…

Biological Physics · Physics 2021-03-31 Ushasi Roy , Andrew Mugler

Ecological and evolutionary dynamics have been historically regarded as unfolding at broadly separated timescales. However, these two types of processes are nowadays well documented to much more tightly than traditionally assumed,…

Populations and Evolution · Quantitative Biology 2021-11-17 José Camacho Mateu , Matteo Sireci , Miguel A. Muñoz

We compare and contrast the long-time dynamical properties of two individual-based models of biological coevolution. Selection occurs via multispecies, stochastic population dynamics with reproduction probabilities that depend nonlinearly…

Populations and Evolution · Quantitative Biology 2011-11-10 Per Arne Rikvold

Agent-based stochastic models for finite populations have recently received much attention in the game theory of evolutionary dynamics. Both the ultimate fixation and the pre-fixation transient behavior are important to a full understanding…

Populations and Evolution · Quantitative Biology 2015-03-17 Da Zhou , Hong Qian

We investigate the phenomenology emerging from a 2-species dynamics under the scenario of a quasi-neutral competition within a metapopulation framework. We employ stochastic and deterministic approaches, namely spatially-constrained…

Populations and Evolution · Quantitative Biology 2021-02-05 Marcelo A. Pires , Nuno Crokidakis , Silvio M. Duarte Queirós

Understanding why strains with different metabolic pathways that compete for a single limiting resource coexist is a challenging issue within a theoretical perspective. Previous investigations rely on mechanisms such as group or spatial…

Populations and Evolution · Quantitative Biology 2016-06-29 Lenin Fernández , André Amado , Fernando Fagundes Ferreira , Paulo R. A. Campos

The problem of natural selection in dispersal-structured populations consisting of individuals characterized by different diffusion coefficients is studied. The competition between the organisms is taken into account through the assumption…

Adaptation and Self-Organizing Systems · Physics 2020-05-01 E. Heinsalu , D. Navidad Maeso , M. Patriarca